DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adat1 and adarb1a

DIOPT Version :9

Sequence 1:	NP_001260450.1	Gene:	Adat1 / 34787	FlyBaseID:	FBgn0028658	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_571685.2	Gene:	adarb1a / 58134	ZFINID:	ZDB-GENE-000627-2	Length:	720	Species:	Danio rerio

Alignment Length:	403	Identity:	122/403 - (30%)
Similarity:	183/403 - (45%)	Gaps:	56/403 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IAELCLKKFESLPKT-GKPTANQWTILAGIV-EFNRNTEACQLVSLGCGTKCIGESKLCPNGLIL 74
            ::.|.:.||..|... ..|.|.: .:|||:| ...::....|::.:..|||||....:...||.|
Zfish   346 VSRLVVDKFSELTDNFSSPHARR-KVLAGVVMTTGKDVMDAQVICVTTGTKCINGEYMSDRGLAL 409

  Fly    75 NDSHAEVLARRGFLRFLYQELK----------QDRIFHWNSTLSTYDMDEHVEFHFLSTQTPCGD 129
            ||.|||::|||..:|:||.:|:          :..||.|.|. ..|.:.:.::||...:.:||||
Zfish   410 NDCHAEIIARRSLIRYLYNQLEYFLSDSTEEHEKSIFRWCSE-HGYRLKDDIQFHLYISTSPCGD 473

  Fly   130 ACILEEEQPAARAKRQRLDEDSEMVYTGAKLISDLSDDPMLQTPGALRTKPG--RGERTLSMSCS 192
            |.|....:..|..:..|............|:.|.....| ::|...::|..|  :|||.|:||||
Zfish   474 ARIFSPHEAGAEDQGDRHPNRKARGQLRTKIESGEGTIP-VRTSNTIQTWDGVLQGERLLTMSCS 537

  Fly   193 DKIARWNVIGVQGALLDVLISKPIYFSSLNFCCDDAQLESLERAIFKRFDCRTFKHTRFQPQRPQ 257
            |||||||||||||:||. ..::||||||| ........:.|.||:::|..........|:..||.
Zfish   538 DKIARWNVIGVQGSLLS-YFTEPIYFSSL-ILGSLYHADHLSRAMYQRIADMDDIPPPFRINRPL 600

  Fly   258 IN-------IDPGIRFEFSQRSDWQPSPNGLIWSQVPEELRPYEISVNGKRQGVTKKKMKTSQAA 315
            ::       ..||....||  .:|.....||            || :|    ..|.|.....|:.
Zfish   601 LSGISNTEARQPGKAPNFS--VNWTVGDQGL------------EI-IN----ATTGKDDLGRQSQ 646

  Fly   316 LAISKYKLFLTFLELVKFNPKLSEMFDQQLSDPERIAYASCKDLARDYQFAWREIKEKYFL---- 376
            |.  |:.|:..:   |..:.||||....:.|.|.  :|...|..|.:|..|.:.:.:.::.
Zfish   647 LC--KHALYSRW---VCLHAKLSETLRIRGSRPG--SYHEAKQGAVEYHEAKQTLFKAFYKAGLG 704

  Fly   377 QWTKKPHELLDFN 389
            .|.:||.|...|:
Zfish   705 AWVEKPIEQDQFS 717

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adat1	NP_001260450.1	ADEAMc	7..389	CDD:214718	121/401 (30%)
adarb1a	NP_571685.2	DSRM	95..157	CDD:214634
		DSRM	254..303	CDD:238007
		ADEAMc	341..717	CDD:214718	121/401 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2777
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D274045at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10910
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920