DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adat1 and Adad1

DIOPT Version :9

Sequence 1:	NP_001260450.1	Gene:	Adat1 / 34787	FlyBaseID:	FBgn0028658	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_033376.2	Gene:	Adad1 / 21744	MGIID:	103258	Length:	619	Species:	Mus musculus

Alignment Length:	367	Identity:	99/367 - (26%)
Similarity:	155/367 - (42%)	Gaps:	80/367 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 QLVSLGCG----TKCIGESKLCPNGLILNDSHAEVLARRGFLRFLYQEL----------KQDRIF 101
            ::|::|.|    ::||.     |||.:|:|:||.|.|||..||:.|::|          .:..||
Mouse   288 EVVAIGTGEYNYSQCIK-----PNGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIF 347

  Fly   102 HWNSTLSTYDMDEHVEFHFLSTQTPCGDACILEEEQ--PAARAKRQRLDEDSEMVYTGAKLISDL 164
            ......:...:.:::..:....|.|.|.|.|..:.:  |.:.:..:..:|.|..|....|:...:
Mouse   348 CTEPASNLLTLKQNINLYLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELSLHVAVEGKIYLTV 412

  Fly   165 --SDDPMLQTPGALRTKPGRGERTLSMSCSDKIARWNVIGVQGALLDVLISKPIYFSSL---NFC 224
              |.|.:              .|..|||.|||:.||.|:|||||||...| :|:|.||:   :..
Mouse   413 YCSADGV--------------NRVNSMSSSDKLTRWEVLGVQGALLSHFI-QPVYISSILVGDGN 462

  Fly   225 CDDAQLESLERAIFKRF-DCRTFKHTRFQ-PQRPQINIDP---GIRFEFSQRS---DWQPSPNGL 281
            |:|.:  .||.||.:|. |..|.|...|. ..||.|::.|   .::.....:|   :|....|.|
Mouse   463 CNDTR--GLEIAINQRVDDALTSKLPMFYLVNRPHISLVPTAYPLQINLDHKSLSLNWAQGDNSL 525

  Fly   282 IWSQVPEELRPYEI--SVNGKRQGVTKKKMKTSQAALAISKYKLFLTFLELVKFNPKLSEMFDQQ 344
                        ||  .:|||   :|:.....|..::|....|..:    |.:||....|.....
Mouse   526 ------------EIVDGLNGK---ITESSPFKSGLSMASRLCKAAM----LSRFNLLAKEAKTDD 571

  Fly   345 LSDPERIAYASCKDLARDYQFAWREIKEKYFLQ-----WTKK 381
            |.  |...|.:.|.::..||.| :.:.:.|..|     |..|
Mouse   572 LL--EARTYHAAKCMSGPYQEA-KALLKAYLQQHGYGSWIVK 610

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adat1	NP_001260450.1	ADEAMc	7..389	CDD:214718	99/367 (27%)
Adad1	NP_033376.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..50
		DSRM	139..204	CDD:214634
		ADEAMc	246..618	CDD:214718	99/367 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2777
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D274045at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820