DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adat1 and adr-1

DIOPT Version :9

Sequence 1:	NP_001260450.1	Gene:	Adat1 / 34787	FlyBaseID:	FBgn0028658	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_492153.2	Gene:	adr-1 / 172542	WormBaseID:	WBGene00000079	Length:	964	Species:	Caenorhabditis elegans

Alignment Length:	407	Identity:	84/407 - (20%)
Similarity:	160/407 - (39%)	Gaps:	89/407 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MCDNK-KPTVKEIAELCLKKFESLPKTGK-PTANQWTILAGIVEFNRNTEACQLVSLGCGTKCIG 63
            |.::| .|..:.|||.|.:::..:.:..: |.:|   :.|..:..|...|. :::::|...:.|.
Worm   619 MTESKVSPLCRHIAEFCKREYHQMTEYYQIPPSN---LFAAFLLVNAQEEK-RVLAMGSSIQYIV 679

  Fly    64 ESKLC--PNGLILNDSHAEVLARRGFLRFLYQELKQDRIFHWNSTLSTYDMDE--------HVEF 118
            |....  .||..|....|.:||||..|:....||..     .:|..|.::..|        ::..
Worm   680 EPDTLSGANGTSLLHLDAIILARRAMLKAFIHELST-----VDSECSIFEKKEEGKAALKPNLRL 739

  Fly   119 HFLSTQTPCGDACILEEEQPAARAKRQRLDEDSEMVYTGAKLISDLSDDPMLQTPGALRTKPGRG 183
            ...|..:|   .||...:..|.:          ::.|.....::.:.||       .|..:..:.
Worm   740 VLYSNYSP---PCIHAVDDAATK----------KLSYVTPTNLTCVPDD-------VLTYEQIKE 784

  Fly   184 ERTLSMSC-SDKIARWNVIGVQGALLDVLISKPIYFSSLNFCCDDAQL--ESLERAIFKRFDCRT 245
            .::|.:.| :||:.:||.:|:|||||..:: .||:..:: |...:|.:  |||..|:..|.....
Worm   785 TKSLRVHCTADKLFKWNTLGIQGALLSNVL-HPIFIDNI-FFGSEAPVSDESLSYALQGRLGPNE 847

  Fly   246 FKHTRFQPQRP-QINIDPGIRFEFSQRSDWQPSPNGLIWSQVPEELRPYEISVNGKRQGVTKKKM 309
            .:........| |:.:..||..               :|.:..:.:...:.:.....:|...:
Worm   848 NEREIIVESMPVQMRMHMGISH---------------LWHRGVDSVETLDYNTGRTSKGSPSR-- 895

  Fly   310 KTSQAALAISKYKLFLTFLELVKFNPKLSEMFDQQLSDPERIAYASCKDLARDYQFAWREIKEKY 374
                    :.|.::|..:.:|        ...||.:     :.||..|::|.:||:..:...||.
Worm   896 --------VCKAEIFEAYRKL--------NGVDQAV-----VNYAKAKEMASEYQYEKKVFYEKL 939

  Fly   375 ----FLQWTKKPHELLD 387
                ..:|..||.||:|
Worm   940 EAAGLGKWQTKPAELVD 956

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adat1	NP_001260450.1	ADEAMc	7..389	CDD:214718	82/400 (21%)
adr-1	NP_492153.2	DSRM	180..238	CDD:214634
		DSRM	528..600	CDD:214634
		ADEAMc	630..958	CDD:214718	81/396 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10910
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010