DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Adat1 and adarb2

DIOPT Version :9

Sequence 1:	NP_001260450.1	Gene:	Adat1 / 34787	FlyBaseID:	FBgn0028658	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	XP_031759801.1	Gene:	adarb2 / 100496062	XenbaseID:	XB-GENE-1011921	Length:	744	Species:	Xenopus tropicalis

Alignment Length:	422	Identity:	118/422 - (27%)
Similarity:	171/422 - (40%)	Gaps:	104/422 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IAELCLKKFESLPKTGKPTANQWTILAGIVEFNRNTE--ACQLVSLGCGTKCIGESKLCPNGLIL 74
            :.:|.::||:.|........::...||.|| ..|..:  ..|:::|..|||||....|...||::
Frog   370 VYQLVIQKFQELTDHFSSVCSRHKALAAIV-MTRGLDLRQAQVIALSSGTKCINGEYLNDQGLVV 433

  Fly    75 NDSHAEVLARRGFLRFLYQELKQDRIFH-------WNSTL------STYDMDEHVEFHFLSTQTP 126
            ||.|||::.||.||.|||.:|:    .|       |..::      ..|.:.|::.||...:.:|
Frog   434 NDCHAEIIVRRAFLHFLYTQLE----LHLSKQRTDWEHSIFIRLKEGGYRLRENIMFHLYVSTSP 494

  Fly   127 CGDACILEEEQPAARAKRQRLDEDSEMVYTGAKLISDLS--DDPMLQTPGALRTK--------PG 181
            ||||               ||....|       :.|||:  ...:.:..|.||||        |.
Frog   495 CGDA---------------RLHSPYE-------ITSDLNRFKHIVRKFRGHLRTKIESGEGTIPV 537

  Fly   182 R-------------GERTLSMSCSDKIARWNVIGVQGALLDVLISKPIYFSSLNFCCDDAQLE-- 231
            |             ||:.::|||:|||.|||::|:|||||...|. |||..|:..    ..|.
Frog   538 RSRAAVQTWDGVLSGEQLVTMSCTDKITRWNILGLQGALLSHFID-PIYLQSIIV----GSLHHT 597

  Fly   232 -SLERAIFKRFDCRTFKHTRFQPQRPQINIDPGIRFEFSQRSDWQP--SPN-GLIWSQVPEELRP 292
             .|.|.:..|.:........:....|.::   |:    |.....||  ||| .|.|.....||..
Frog   598 GHLSRVMSHRIEDLGNLPAPYWHHHPLLS---GV----SNAEARQPGKSPNFSLNWIVGSTELEV 655

  Fly   293 YEISVNGKR-----QGVTKKKMKTSQAALAISKYKLFLTFLELVKFNPKLSEMFDQQLSDPERIA 352
            .. :..|||     ..:.|:.:.|..|.|    |....|.:...|..|.:  ..|.:|:.|   .
Frog   656 IN-ATTGKRSCGSSSRLCKRALYTRWARL----YGKLSTRIGNHKETPAV--YCDAKLAHP---T 710

  Fly   353 YASCKDLARDYQFAWREIKEKYFLQWTKKPHE 384
            |.|.|      |..::.|:......|.|||.|
Frog   711 YQSVK------QQMFKAIQRSGLGTWVKKPPE 736

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adat1	NP_001260450.1	ADEAMc	7..389	CDD:214718	118/422 (28%)
adarb2	XP_031759801.1	DSRM_RED2_rpt1	121..194	CDD:380725
		DSRM_RED2_rpt2	275..348	CDD:380728
		ADEAMc	365..741	CDD:214718	118/422 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D274045at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010