DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adat1 and adad1

DIOPT Version :9

Sequence 1:	NP_001260450.1	Gene:	Adat1 / 34787	FlyBaseID:	FBgn0028658	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_001116945.1	Gene:	adad1 / 100144718	XenbaseID:	XB-GENE-493326	Length:	584	Species:	Xenopus tropicalis

Alignment Length:	418	Identity:	114/418 - (27%)
Similarity:	175/418 - (41%)	Gaps:	92/418 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VKEIAELCLKKFESLPKTGKPTANQWTILAGIVEFNRNTEACQLVSLGCGTKCIGESKLCPNGLI 73
            :||.....:.|:......|.      ::.|.::|  :..:..::|::|.|....|:| |..:|.:
Frog   219 IKETFTNLISKYPEYESCGS------SLAAFVIE--KGGQNWEVVAVGTGEFNYGQS-LQSDGRV 274

  Fly    74 LNDSHAEVLARRGFLRFLYQEL---------KQDR-IFHWNSTLSTYDMDEHVEFHFLSTQTPCG 128
            |:||||.|:|||..||:.|::|         ..|: ||......:...:..:........|.|.|
Frog   275 LHDSHAIVVARRSLLRYFYRQLLLFYSGNNGMMDKSIFCTEPATNLLALKPNFNIFLYMNQLPKG 339

  Fly   129 DA------CILEEEQPAARAKRQRLDEDSEMVYTGAKLISDLSDDPMLQTPGALRTKPGRGE--- 184
            .|      |:    .|.:.:..:..|:.|..|....|.|           |.|..:    ||
Frog   340 AAQTNPQLCL----SPHSLSAHEANDKLSLHVSVEGKNI-----------PAAYYS----GEIVH 385

  Fly   185 RTLSMSCSDKIARWNVIGVQGALLDVLISKPIYFSSL---NFCCDDAQLESLERAIFKRF-DCRT 245
            ...|||.:||:.||.|:|||||||.|.| :|:|.|::   |..|.|.:  .||.|:.:|. |..|
Frog   386 NLYSMSSTDKLTRWEVLGVQGALLSVFI-QPVYISTIIVGNAACSDTR--GLEIAVKQRIDDALT 447

  Fly   246 FKHTRFQ-PQRP---------QINIDPGIRFEFSQRSDWQPSPNGLIWSQVPEELRPYEISVNGK 300
            .|...|. ..||         |.|:||..|            ...|.|||....:...: :|.||
Frog   448 SKLPMFYLVNRPYISIVSSTHQTNMDPVNR------------SLSLNWSQGDACVEVVD-AVRGK 499

  Fly   301 RQGVTKKKMKTSQAALAISKYKLFLTFLELVKFNPKLSEMFDQQLSDPERIAYASCKDLARDYQF 365
            .  |.:...| |.:.||....|..:    |.:||..:.|...:.:: |: ::|...|.||..||.
Frog   500 T--VERSPFK-SGSCLASRLCKAAM----LCRFNLVVKESKREAIA-PD-LSYHEAKHLAGPYQE 555

  Fly   366 AWREIKEKYFLQ-----WTKKPHELLDF 388
            | :.:.:.||.|     |..||..:.:|
Frog   556 A-KCLLKAYFKQQGFGSWIVKPPIIDEF 582

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adat1	NP_001260450.1	ADEAMc	7..389	CDD:214718	114/418 (27%)
adad1	NP_001116945.1	DSRM	97..162	CDD:214634
adad1	NP_001116945.1	A_deamin	256..576	CDD:280326	104/365 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D274045at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010