DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adat1 and adarb1

DIOPT Version :9

Sequence 1:	NP_001260450.1	Gene:	Adat1 / 34787	FlyBaseID:	FBgn0028658	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	XP_031748314.1	Gene:	adarb1 / 100124739	XenbaseID:	XB-GENE-954085	Length:	756	Species:	Xenopus tropicalis

Alignment Length:	409	Identity:	114/409 - (27%)
Similarity:	185/409 - (45%)	Gaps:	69/409 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IAELCLKKFESLPKTGKPTANQWTILAGIV-EFNRNTEACQLVSLGCGTKCIGESKLCPNGLILN 75
            ::.|.:.||..|.........:..:|||:| ....:.:..|::.:..|||||....:...||.||
Frog   383 VSRLVVDKFSDLTDNFTSPHARRKVLAGVVMTTGTDVKDAQVICVSTGTKCINGEYMSDRGLALN 447

  Fly    76 DSHAEVLARRGFLRFLYQELK--------QDRIFHWNSTLSTYDMDEHVEFHFLSTQTPCGDACI 132
            |.|||:::||..:||||.:|:        |.|.....|....:.:.::|:||...:.:|||||.|
Frog   448 DCHAEIISRRSLVRFLYTQLELFLSTKEDQQRSIFMKSERGGFKLKDNVQFHLYISTSPCGDARI 512

  Fly   133 L------EEEQPAARAKRQRLDEDSEMVYTGAKLISDLSDDPMLQTPGALRTKPGRGERTLSMSC 191
            .      :|:|......|:...:....:.:|...|...|...:....|.|     :|||.|:|||
Frog   513 FSPHEAGQEDQGDRHPNRKARGQLRTKIESGEGTIPVRSSSTIQTWDGVL-----QGERLLTMSC 572

  Fly   192 SDKIARWNVIGVQGALLDVLISKPIYFSSLNFCCDDAQL---ESLERAIFKRF-DCRTFKHTRFQ 252
            |||:|||||:|:||:||.:.: :|||.||:..    ..|   :.|.||:::|. |.....|. :.
Frog   573 SDKLARWNVVGIQGSLLSLFV-EPIYLSSIIL----GSLYHGDHLSRAVYQRISDIEDLPHL-YA 631

  Fly   253 PQRPQIN-------IDPGIRFEFSQRSDWQPSPNGLIWSQVPEELRPYEISVNGKRQGVTKKKMK 310
            ..:|.::       ..||....||  .:|....:||            |: :|     .|..|.:
Frog   632 LNKPLLSGISNAEARQPGKAPSFS--VNWAVGDSGL------------EV-IN-----ATTGKDE 676

  Fly   311 TSQAALAISKYKLFLTFLELVKFNPKLSEMFDQQLSDPERIAYASCKDLARDYQFAWREIKEKYF 375
            ..:|: .:.|:.|:..::   :.:.|||.....::.  :...|...|..|.:||.| :|...|.|
Frog   677 MGRAS-RLCKHALYSRWM---RIHAKLSSSVRCKIG--KLNVYHDTKHSAVEYQSA-KECVFKVF 734

  Fly   376 LQ-----WTKKPHELLDFN 389
            .:     |.|||.|...|:
Frog   735 QKSGLGAWVKKPIEQDQFS 753

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adat1	NP_001260450.1	ADEAMc	7..389	CDD:214718	113/407 (28%)
adarb1	XP_031748314.1	DSRM_RED1_rpt1	132..203	CDD:380724
		DSRM_RED1_rpt2	288..357	CDD:380727
		ADEAMc	378..753	CDD:214718	113/407 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D274045at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2305
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.040