DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH1 and ACA7

DIOPT Version :9

Sequence 1:	NP_523561.1	Gene:	CAH1 / 34786	FlyBaseID:	FBgn0027844	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_172287.1	Gene:	ACA7 / 837326	AraportID:	AT1G08080	Length:	275	Species:	Arabidopsis thaliana

Alignment Length:	267	Identity:	66/267 - (24%)
Similarity:	110/267 - (41%)	Gaps:	59/267 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 EENGPAHWAKEYPQ----ASGHRQSPVDITPSSAKKGSELNVAPLKWKYVPEHTKSLVNPGY--- 66
            :|.||..|.:..|:    ..|..|||:|:........|.|  ..|...|.|.:. :|.|.|:
plant    46 DEKGPERWGELKPEWEMCGKGEMQSPIDLMNERVNIVSHL--GRLNRDYNPSNA-TLKNRGHDIM 107

  Fly    67 ------CWRVDVNGADSELTGGPLGDQIFKLEQFHCHWGCTDSKGSEHTVDGVSYSGELHLVHWN 125
                  ...:.:||.:            ::|:|.|.|      ..||||::|..::.|||:||..
plant   108 LKFEDGAGTIKINGFE------------YELQQLHWH------SPSEHTINGRRFALELHMVHEG 154

  Fly   126 TTKYKSFGEAAAAPDGLAVLGVFLKAGNHHAELDKVTSLLQFVLHKGDRVTLPQGCDPGQLLPDV 190
            ..:            .:||:.|..|.|.....:..:...|:.:....:........||.::....
plant   155 RNR------------RMAVVTVLYKIGRADTFIRSLEKELEGIAEMEEAEKNVGMIDPTKIKIGS 207

  Fly   191 HTYWTYEGSLTTPPCSESVIWIVFKTPIEVSDDQLNAMR-------NLNAYDVKEECPCNEFNGK 248
            ..|:.|.||||||||:::|.|.|.:....|:..|:..:|       |.||..|:   |.|:   :
plant   208 RKYYRYTGSLTTPPCTQNVTWSVVRKVRTVTRKQVKLLRVAVHDDANSNARPVQ---PTNK---R 266

  Fly   249 VINNFRP 255
            :::.:||
plant   267 IVHLYRP 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH1	NP_523561.1	Carb_anhydrase	5..263	CDD:215000	66/267 (25%)
ACA7	NP_172287.1	alpha_CA_prokaryotic_like	49..270	CDD:239398	63/259 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	1.000	Domainoid score	I2610
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I2251
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	1	1.000	-	-		mtm1014
orthoMCL	1	0.900	-	-		OOG6_100138
Panther	1	1.100	-	-	O	PTHR18952
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.960