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Protein Alignment CAH1 and CA1

DIOPT Version :9

Sequence 1:	NP_523561.1	Gene:	CAH1 / 34786	FlyBaseID:	FBgn0027844	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001122301.1	Gene:	CA1 / 759	HGNCID:	1368	Length:	261	Species:	Homo sapiens

Alignment Length:	273	Identity:	120/273 - (43%)
Similarity:	151/273 - (55%)	Gaps:	26/273 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SHHWGYTEENGPAHWAKEYPQASGHRQSPVDITPSSAKKGSELNVAPLKWKYVPEHTKSLVNPGY 66
            |..|||.::|||..|:|.||.|:|:.||||||..|..|..:.|.  |:...|.|...|.::|.|:
Human     3 SPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLK--PISVSYNPATAKEIINVGH 65

  Fly    67 CWRVDVNGAD--SELTGGPLGDQIFKLEQFHCHWGCTDSKGSEHTVDGVSYSGELHLVHWNTTKY 129
            .:.|:....|  |.|.|||..|. ::|.|||.|||.|:..|||||||||.||.|||:.|||:.||
Human    66 SFHVNFEDNDNRSVLKGGPFSDS-YRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKY 129

  Fly   130 KSFGEAAAAPDGLAVLGVFLKAGNHHAELDKVTSLLQFVLHKGDRVTLPQGCDPGQLLPDVHTYW 194
            .|..|||:..|||||:||.:|.|..:.:|.||...||.:..||.|... ...||..|||....:|
Human   130 SSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPF-TNFDPSTLLPSSLDFW 193

  Fly   195 TYEGSLTTPPCSESVIWIVFKTPIEVSDDQLNAMRNL-------NAYDVKEECPCNEFNGKVINN 252
            ||.||||.||..|||.||:.|..|.||.:||...|:|       ||..::             :|
Human   194 TYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQ-------------HN 245

  Fly   253 FRPPLPLGKRELR 265
            .||..||..|.:|
Human   246 NRPTQPLKGRTVR 258

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.