Protein Alignment CAH1 and CA10

DIOPT Version :9

• Sequence 1: NP_523561.1
• Gene: CAH1 / 34786
• FlyBaseID: FBgn0027844
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_001076002.1
• Gene: CA10 / 56934
• HGNCID: 1369
• Length: 328
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 89/306 - (29%)
• Similarity: 141/306 - (46%)
• Gaps: 78/306 - (25%)

  Fly     9 EENGP----AHWA-KEYPQAS--------------------GHRQSPVDI-----------TPSS 37
            ::|.|    ..|| ||..|.|                    |.|||||:|           ||..
Human    22 QQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPVNIETSHMIFDPFLTPLR 86

  Fly    38 AKKGSELNVAPLKWKYVPEHTKSLVNPG--YCWRVD----VNGADSELTGGPLGDQIFKLEQFHC 96
            ...|..            :.:.::.|.|  ...|:|    ||     ::|||: ....:||:...
Human    87 INTGGR------------KVSGTMYNTGRHVSLRLDKEHLVN-----ISGGPM-TYSHRLEEIRL 133

  Fly    97 HWGCTDSKGSEHTVDGVSYSGELHLVHWNTTKYKSFGEAAAAPDGLAVLGVFLKAG-------NH 154
            |:|..||:||||.::|.::|||:.|:|:|...|.:..|||.:|:||.|:.:|:|..       |.
Human   134 HFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNR 198

  Fly   155 HAELDKVTSLLQFVLHKGDRVTLPQGCDPGQLLPDVHTYWTYEGSLTTPPCSESVIWIVFKTPIE 219
            ....|.:|.    :.:|.|...| ||.:..:|.|:..::.||:||:|.|||.|:..||:...|:.
Human   199 MLNRDTITR----ITYKNDAYLL-QGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVY 258

  Fly   220 VSDDQLNAMRNLNAYDVKEECPCNEFNGKVINNFRPPLPLGKRELR 265
            ::..|::::|.|:     :..|...|. .:.:||||..||..|.:|
Human   259 ITRMQMHSLRLLS-----QNQPSQIFL-SMSDNFRPVQPLNNRCIR 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH1	NP_523561.1	Carb_anhydrase	5..263	CDD:215000	87/302 (29%)
CA10	NP_001076002.1	alpha_CARP_X_XI_like	46..302	CDD:239395	81/282 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820