DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH1 and ca12

DIOPT Version :9

Sequence 1:	NP_523561.1	Gene:	CAH1 / 34786	FlyBaseID:	FBgn0027844	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001016431.1	Gene:	ca12 / 549185	XenbaseID:	XB-GENE-1015246	Length:	335	Species:	Xenopus tropicalis

Alignment Length:	266	Identity:	89/266 - (33%)
Similarity:	134/266 - (50%)	Gaps:	20/266 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 HHWGYTEENGPAHWAKEYPQASGHRQSPVDITPSSAKKGSELNVAPLK---WKYVPEHTKSLVNP 64
            |.|.|....|...|.|.|....|..|||:||.....:..|.|.  |:|   :...|..:.:|.|.
Frog    21 HGWAYIGTKGEKSWPKNYEFCGGVYQSPIDIHQDILQYDSSLQ--PVKLNGYNVSPAESFTLSNN 83

  Fly    65 GYCWRVDVNGADSELTGGPLGDQIFKLEQFHCHWGCTDS-KGSEHTVDGVSYSGELHLVHWNTTK 128
            |:..::.: ....::...|..   :...|.|.|||...: |||||.::|..::||:|||::|:.|
Frog    84 GHTVQMSL-VPTMQIKIAPFH---YTASQLHLHWGQRGTQKGSEHCIEGKRFAGEVHLVNYNSDK 144

  Fly   129 YKSFGEAAAAPDGLAVLGVFLKAGNHHAELDKVTSLLQFVLHKGDRVTLPQGCDPGQLLPD-VHT 192
            |.....|....|||||||:.|:.|..:...:|:.|.|..:.:|...|.: .|.:..:|||. :..
Frog   145 YSDITTAMKESDGLAVLGILLEVGPFNPTFEKIISQLHSIGYKDQSVQI-AGFNVQELLPKRLDE 208

  Fly   193 YWTYEGSLTTPPCSESVIWIVFKTPIEVSDDQLNAMRN-LNAYDVKEECPCNEFNGKVINNFRPP 256
            |:.||||||||||..||:|.||:.|:.:|::||..:.. |.:.|..|..       ::.||:|..
Frog   209 YYRYEGSLTTPPCYPSVLWTVFRNPVTISEEQLITLETALYSTDRNESV-------QMTNNYRQL 266

  Fly   257 LPLGKR 262
            .|.|.|
Frog   267 QPHGDR 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH1	NP_523561.1	Carb_anhydrase	5..263	CDD:215000	88/264 (33%)
ca12	NP_001016431.1	alpha_CA_XII_XIV	30..278	CDD:239400	86/257 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010