DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH1 and CAH6

DIOPT Version :9

Sequence 1:	NP_523561.1	Gene:	CAH1 / 34786	FlyBaseID:	FBgn0027844	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001097987.1	Gene:	CAH6 / 43701	FlyBaseID:	FBgn0039838	Length:	298	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	89/275 - (32%)
Similarity:	128/275 - (46%)	Gaps:	38/275 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 HWGYTEENGPAHWAKEYPQASGHRQSPVDITPSSAKKGSELNVAPL------KWKYVPEHTKSLV 62
            ||.| |.|| .:|....  ::|.||||:.:....:.      :.||      .:........:|:
  Fly    29 HWDY-ETNG-QNWGGIC--STGERQSPISLNVQKSL------IVPLPRIVFGNYDVKLRGPLTLL 83

  Fly    63 NPGYCWRVDV----NGADSELTGGPLGDQIFKLEQFHCHWGCTDSKGSEHTVDGVSYSGELHLVH 123
            |.|:...|::    ||....:|||.|..: |..|.||.|||...|:||||:::...:..|:|:||
  Fly    84 NNGHTAHVEIPETANGNKPFITGGLLKGR-FVAEAFHFHWGSPSSRGSEHSINQQRFDVEMHIVH 147

  Fly   124 WNTTKYKSFGEAAAAPDGLAVLGVFLKAGNH----HAELDKVTSLLQFVLHKGDRVTLPQGCDPG 184
            .| .||....||....||:||:||.||...:    ...|.||.|.|..|.....:.|:|.|...|
  Fly   148 RN-EKYGDIDEAKNKKDGIAVIGVMLKIVKNPNRIFPGLSKVMSALPRVTKYNAKTTIPGGLSLG 211

  Fly   185 QLLPDVH--TYWTYEGSLTTPPCSESVIWIVFKTPIEVSDDQLNAMRNLNAYDVKEECPCNEFNG 247
            |:|.:|:  .::||.||||||.|.:||.|.||...:.|....::....|.          :....
  Fly   212 QMLGNVNPRDFFTYRGSLTTPLCEQSVTWTVFSQVLPVPYSSVSKFWKLR----------DSEGH 266

  Fly   248 KVINNFRPPLPLGKR 262
            ::|||||...|...|
  Fly   267 RLINNFRDIQPRNGR 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH1	NP_523561.1	Carb_anhydrase	5..263	CDD:215000	88/274 (32%)
CAH6	NP_001097987.1	Carb_anhydrase	30..282	CDD:215000	88/274 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446782
Domainoid	1	1.000	91	1.000	Domainoid score	I2610
eggNOG	1	0.900	-	-		E1_COG3338
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I2251
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D113047at6656
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	1	1.000	-	-		mtm1014
orthoMCL	1	0.900	-	-		OOG6_100138
Panther	1	1.100	-	-	P	PTHR18952
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
	11	10.800