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Protein Alignment CAH1 and CA13

DIOPT Version :9

Sequence 1:	NP_523561.1	Gene:	CAH1 / 34786	FlyBaseID:	FBgn0027844	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_940986.1	Gene:	CA13 / 377677	HGNCID:	14914	Length:	262	Species:	Homo sapiens

Alignment Length:	264	Identity:	123/264 - (46%)
Similarity:	152/264 - (57%)	Gaps:	14/264 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 WGYTEENGPAHWAKEYPQASGHRQSPVDITPSSAKKGSELNVAPLKWKYVPEHTKSLVNPGYCWR 69
            |||.|.|||.||.:.:|.|.|.:|||::|.....|..|.|.  ||..||.|...|.:.|.|:.:.
Human     6 WGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLR--PLSIKYDPSSAKIISNSGHSFN 68

  Fly    70 VDVNGAD--SELTGGPLGDQIFKLEQFHCHWGCTDSKGSEHTVDGVSYSGELHLVHWNTTKYKSF 132
            ||.:..:  |.|.||||... ::|.|.|.|||..|..||||.||||||:.|||:||||:.||.||
Human    69 VDFDDTENKSVLRGGPLTGS-YRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSF 132

  Fly   133 GEAAAAPDGLAVLGVFLKAGNHHAELDKVTSLLQFVLHKGDRVTLPQGCDPGQLLPDVHTYWTYE 197
            .|||..|||||||||||:.|..:::|.|:|..|..:..|| :.|.....|...|||....||||.
Human   133 VEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKG-KQTRFTNFDLLSLLPPSWDYWTYP 196

  Fly   198 GSLTTPPCSESVIWIVFKTPIEVSDDQLNAMRNLNAYDVKEECPC-NEFNGKVINNFRPPLPLGK 261
            ||||.||..|||.|||.|.||.:|..||...|:|       .|.. .|....:::|.|||.||..
Human   197 GSLTVPPLLESVTWIVLKQPINISSQQLAKFRSL-------LCTAEGEAAAFLVSNHRPPQPLKG 254

  Fly   262 RELR 265
            |::|
Human   255 RKVR 258

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.