DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH1 and cah-6

DIOPT Version :9

Sequence 1:	NP_523561.1	Gene:	CAH1 / 34786	FlyBaseID:	FBgn0027844	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_491189.1	Gene:	cah-6 / 189049	WormBaseID:	WBGene00000284	Length:	319	Species:	Caenorhabditis elegans

Alignment Length:	251	Identity:	81/251 - (32%)
Similarity:	119/251 - (47%)	Gaps:	21/251 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 GHRQSPVDITPSSAKKGSELNVAPLKWKYVPEHTKSLVNPGYCWRVDVNGADSELTGGPLGDQIF 89
            |..|||:||.|.....|..|..|..:..|........||.|....:...|..|||....|.::.:
Worm    65 GRTQSPIDIVPVITAFGEHLQNAHFEVTYESTGEFKAVNDGNSIWLMREGNSSELAISFLPEEQY 129

  Fly    90 KLEQFHCHWGCTDSKGSEHTVDGVSYSGELHLVHWNTTKYKSFGEAAAAPDGLAVLGVFL-KAGN 153
            .|:..:.||......|||||:.||.|:||:||:|.| |::.:..:|...|:|:..:.||| ::.:
Worm   130 HLDAVNFHWATEPMNGSEHTIGGVGYAGEMHLIHRN-TRFATMADALKQPNGVIAIAVFLNESHD 193

  Fly   154 HHAELDKVTSLLQFVLHKGDRVTLPQGC--DPGQLLP---DVHTYWTYEGSLTTPPCSESVIWIV 213
            .:|....:.:||..|::||....|   |  |.....|   ....:|.||||.||.|..|:|.|||
Worm   194 DNAVFSPLINLLPQVIYKGSECKL---CSFDFQTFFPVAEKTKEFWMYEGSETTDPFRETVNWIV 255

  Fly   214 FKTPIEVSDDQLNAMRNLNA--YDVKEECPCNEFNGKVINNFRPPLPLGKRELREI 267
            .:..:.:|..||:.:|.:.|  ||       .||:.||  ..:|..|:.....|.|
Worm   256 IRAALPISSHQLDKLREVRAGRYD-------EEFSDKV--PMKPLRPIQNPSSRTI 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH1	NP_523561.1	Carb_anhydrase	5..263	CDD:215000	79/245 (32%)
cah-6	NP_491189.1	alpha_CARP_receptor_like	56..304	CDD:239396	81/251 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48615
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.830