back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CAH1 and Car4

DIOPT Version :9

Sequence 1:	NP_523561.1	Gene:	CAH1 / 34786	FlyBaseID:	FBgn0027844	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_031633.1	Gene:	Car4 / 12351	MGIID:	1096574	Length:	305	Species:	Mus musculus

Alignment Length:	286	Identity:	84/286 - (29%)
Similarity:	123/286 - (43%)	Gaps:	81/286 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 GPAHW---AKEYPQASGHRQSPVDITPSSAKKGSELNVAPLKWKYVPEHTKSLVNP--------G 65
            ||..|   .||      ::|||::|..:..|                      |||        |
Mouse    37 GPEKWPGACKE------NQQSPINIVTARTK----------------------VNPRLTPFILVG 73

  Fly    66 Y----CWRVDVNGADSELT--------GGPLGDQIFKLEQFHCHWGCTDSKGSEHTVDGVSYSGE 118
            |    .|.:..|....|:|        ||.|..: ::..|.|.||...:..||||::||..::.|
Mouse    74 YDQKQQWPIKNNQHTVEMTLGGGACIIGGDLPAR-YEAVQLHLHWSNGNDNGSEHSIDGRHFAME 137

  Fly   119 LHLVHWNTTKYKSFGEAAAAPDGLAVLGVFLKAGNHHAELDKVTSLLQFVLHKGDRVTLPQGCDP 183
            :|:||...|..|.     .:.|..|||...::.|      |||....|.::.....::.|.....
Mouse   138 MHIVHKKLTSSKE-----DSKDKFAVLAFMIEVG------DKVNKGFQPLVEALPSISKPHSTST 191

  Fly   184 ------GQLLP---DVHTYWTYEGSLTTPPCSESVIWIVFKTPIEVSDDQ-LNAMRNLNAYDVKE 238
                  ..:||   .::||:.|.||||||.|.|:|||.|:|.||::..:| |...:|| .||..:
Mouse   192 VRESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNL-YYDEDQ 255

  Fly   239 ECPCNEFNGKVINNFRPPLPLGKREL 264
                 :.|.|  :|.||..|||||::
Mouse   256 -----KLNMK--DNVRPLQPLGKRQV 274

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.