Protein Alignment TBX10 and org-1

DIOPT Version :9

• Sequence 1: XP_011543294.1
• Gene: TBX10 / 347853
• HGNCID: 11593
• Length: 430
• Species: Homo sapiens
• Sequence 2: NP_001285019.1
• Gene: org-1 / 31778
• FlyBaseID: FBgn0021767
• Length: 699
• Species: Drosophila melanogaster
• Alignment Length: 295
• Identity: 149/295 - (50%)
• Similarity: 188/295 - (63%)
• Gaps: 36/295 - (12%)

Human    60 SETYPLPTTSSGWEPRLG-SPFPSGPCTSSTGAQAVAEPT------GQ----------------- 100
            |.:..|||..:|...... :|...|...::|.|..|:..|      ||
  Fly   114 SSSVSLPTDYAGVHSEASMAPTAGGTAVTTTSAGGVSASTASKKFKGQHKKDNNSAENGTVKPNS 178

Human   101 --------GPKNPRVSRVTVQLEMKPLWEEFNQLGTEMIVTKAGRRMFPPFQVKILGMDSLADYA 157
                    .|.:|.:::..|.||.|.||::|:..|||||:||.||||||.|||:|.|:|..|.|.
  Fly   179 HNISKGESEPVHPSLAQAIVVLETKALWDQFHAQGTEMIITKTGRRMFPTFQVRIGGLDPHATYI 243

Human   158 LLMDFIPLDDKRYRYAFHSSAWLVAGKADPATPGRVHFHPDSPAKGAQWMRQIVSFDKLKLTNNL 222
            .:|||:|:||||||||||:|.|:|||||||.:|.|:|.||||||.|:.||:|||||||||||||.
  Fly   244 CMMDFVPMDDKRYRYAFHNSCWVVAGKADPISPPRIHVHPDSPAVGSNWMKQIVSFDKLKLTNNQ 308

Human   223 LDDNGHIILNSMHRYQPRFHVVFVDPRKDS--ERYAQENFKSFIFTETQFTAVTAYQNHRITQLK 285
            ||:|||||||||||||||||:|::.|:..|  |.....:|::|||.||.|||||||||.|:||||
  Fly   309 LDENGHIILNSMHRYQPRFHLVYLPPKNASLDENEHSSHFRTFIFPETSFTAVTAYQNQRVTQLK 373

Human   286 IASNPFAKGFRESDLDSWPVAPRPLLSVPARSHSS 320
            |:|||||||||:...:.  |......|:.:.||.|
  Fly   374 ISSNPFAKGFRDDGTND--VTTGGGSSMSSMSHES 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBX10	XP_011543294.1	TBOX	110..300	CDD:238106	129/191 (68%)
org-1	NP_001285019.1	TBOX	195..389	CDD:238106	129/193 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	292	1.000	Domainoid score	I1516
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003320
OrthoInspector	1	1.000	-	-		otm42306
orthoMCL	1	0.900	-	-		OOG6_107409
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3735
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.770