Protein Alignment TBX10 and Tbx10

DIOPT Version :9

• Sequence 1: XP_011543294.1
• Gene: TBX10 / 347853
• HGNCID: 11593
• Length: 430
• Species: Homo sapiens
• Sequence 2: NP_001001320.1
• Gene: Tbx10 / 109575
• MGIID: 1261436
• Length: 385
• Species: Mus musculus
• Alignment Length: 382
• Identity: 314/382 - (82%)
• Similarity: 336/382 - (87%)
• Gaps: 0/382 - (0%)

Human    49 FLSAGLGILAPSETYPLPTTSSGWEPRLGSPFPSGPCTSSTGAQAVAEPTGQGPKNPRVSRVTVQ 113
            |||||||:|||.||.|.|.||:.||.|||:.||||.||.||.|||:||||||||||||||.|.||
Mouse     4 FLSAGLGVLAPPETCPHPETSTSWESRLGTRFPSGSCTMSTEAQAMAEPTGQGPKNPRVSSVMVQ 68

Human   114 LEMKPLWEEFNQLGTEMIVTKAGRRMFPPFQVKILGMDSLADYALLMDFIPLDDKRYRYAFHSSA 178
            ||||||||||||||||||||||||||||.|||||||||:||||||||||||||||||||||||||
Mouse    69 LEMKPLWEEFNQLGTEMIVTKAGRRMFPTFQVKILGMDTLADYALLMDFIPLDDKRYRYAFHSSA 133

Human   179 WLVAGKADPATPGRVHFHPDSPAKGAQWMRQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHV 243
            ||||||||||||||||||||||||||||||||||||||||||||:||||||||||||||||||||
Mouse   134 WLVAGKADPATPGRVHFHPDSPAKGAQWMRQIVSFDKLKLTNNLMDDNGHIILNSMHRYQPRFHV 198

Human   244 VFVDPRKDSERYAQENFKSFIFTETQFTAVTAYQNHRITQLKIASNPFAKGFRESDLDSWPVAPR 308
            |||||||||.||||||||||:|||||||||||||||||||||||||||||||||:|.|||||.||
Mouse   199 VFVDPRKDSARYAQENFKSFVFTETQFTAVTAYQNHRITQLKIASNPFAKGFREADPDSWPVTPR 263

Human   309 PLLSVPARSHSSLSPCVLKGATDREKDPNKASASTSKTPAWLHHQLLPPPEVLLAPATYRPVTYQ 373
            ||||:||||.||||||:|||:.:||||.:|||||:|:||...|:||||.|:||||||||||:.||
Mouse   264 PLLSIPARSRSSLSPCLLKGSAEREKDTSKASASSSRTPTQPHNQLLPAPDVLLAPATYRPLPYQ 328

Human   374 SLYSGAPSHLGIPRTRPAPYPLPNIRADRDQGGLPLPAGLGLLSPTVVCLGPGQDSQ 430
            :||.|:||..|.||.|.||||||||....||....|.||||||..:.:||...|.||
Mouse   329 NLYPGSPSRAGPPRARLAPYPLPNISTAGDQEDPTLAAGLGLLPTSALCLVSNQASQ 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBX10	XP_011543294.1	TBOX	110..300	CDD:238106	182/189 (96%)
Tbx10	NP_001001320.1	TBOX	67..254	CDD:238106	181/186 (97%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	283..310		15/26 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	328..359		18/30 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	378	1.000	Domainoid score	I12213
eggNOG	1	0.900	-	-		E1_KOG3585
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37399
Inparanoid	1	1.050	643	1.000	Inparanoid score	I10017
Isobase	0	0.000	Not matched by this tool.
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG34644
OrthoDB	1	1.010	-	-		D1185429at2759
OrthoFinder	1	1.000	-	-		FOG0003320
OrthoInspector	1	1.000	-	-		oto119773
orthoMCL	1	0.900	-	-		OOG6_107409
Panther	1	1.100	-	-	LDO	PTHR11267
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R13552
SonicParanoid	1	1.000	-	-		X3735
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	17.370