Protein Alignment Sec71 and GNL1

DIOPT Version :9

• Sequence 1: NP_609675.2
• Gene: Sec71 / 34785
• FlyBaseID: FBgn0028538
• Length: 1653
• Species: Drosophila melanogaster
• Sequence 2: NP_001318705.1
• Gene: GNL1 / 833946
• AraportID: AT5G39500
• Length: 1443
• Species: Arabidopsis thaliana
• Alignment Length: 1503
• Identity: 348/1503 - (23%)
• Similarity: 641/1503 - (42%)
• Gaps: 302/1503 - (20%)

  Fly    19 KILADKDIRRSHHSQLKKSCDSALEQIKAELISAGQIAEGNELPCAALPLPKNDAASIINAETYF 83
            :.:||.|       ||:.|...:|::::.::.|    .:.|              ...::...|.
plant    53 RYIADDD-------QLEHSLIHSLKELRKQIFS----WQSN--------------WQYVDPRLYI 92

  Fly    84 LPF---ELACKSRSPRIVVTALDCLQKLIAYGHLTGSIQDSANPG---HLLIDRIVVTIYGC--- 139
            .||   .|:.::.:| |...||..:.|::.....|   .::.|.|   |:::|    .:..|
plant    93 QPFLDVILSDETGAP-ITGVALSSVYKILTLEVFT---LETVNVGEAMHIIVD----AVKSCRFE 149

  Fly   140 FSGPQTDEAVQLQIIKALLTVVTSQHVE-IHEFTLLQAVRTCYDI--YLSSKNLVNQTTARATLT 201
            .:.|.::|.|.::|::.||..|.|:... :....:...|.||..:  ..|||:.:.|..||.|:.
plant   150 VTDPASEEVVLMKILQVLLACVKSKASNGLSNQDICTIVNTCLRVVHQSSSKSELLQRIARHTMH 214

  Fly   202 QMLNVIFARM--------------ENQVYELP-PPNSNP---TNGSIHS-EDCNGSGEESLRDSD 247
            :::..||:::              :|:|..:. .|||..   .||:|.| .|..|:      |.|
plant   215 ELIRCIFSQLPFISPLANECELHVDNKVGTVDWDPNSGEKRVENGNIASISDTLGT------DKD 273

  Fly   248 EVIASELLAEIISAAYNEAMKDQESVGEPEPTLNGNDYSSH-SDHDSVELHSENDAVVTAKFTHI 311
            :. :||::.                   ||..|..::..:. ||..:...:.||..:.......:
plant   274 DP-SSEMVI-------------------PETDLRNDEKKTEVSDDLNAAANGENAMMAPYGIPCM 318

  Fly   312 LQKDAFLVFRALCKLSMKPLPDGHPDPKSHELR----SKVLSLHLLLLILQNAGPVFRSNEMFIM 372
            ::     :|..||.| :....:|..:.:|:.:.    ..:.:|.|:...::..||.||.:...:.
plant   319 VE-----IFHFLCTL-LNVGENGEVNSRSNPIAFDEDVPLFALGLINSAIELGGPSFREHPKLLT 377

  Fly   373 AIKQYLCVALSNNGVSLVPEVFELSLSIFVALLSNFKVHLKRQIEVFFKEIFLNILEA-NSSSFE 436
            .|:..|...|...|:|:.|.:.....||.:.|..|.:..||.|:|.||..:.|.|.:: :.||::
plant   378 LIQDDLFCNLMQFGMSMSPLILSTVCSIVLNLYLNLRTELKVQLEAFFSYVLLRIAQSKHGSSYQ 442

  Fly   437 HKWMVIQALTRICADAQSVVDIYVNYDCDFSAANLFERLVNDLSKIAQGRQALELGANPMQE--K 499
            .:.:.::||..:|.....:.:::.|:|||.:.:|:||.:.|.|||          .|.|:..  .
plant   443 QQEVAMEALVDLCRQHTFIAEVFANFDCDITCSNVFEDVSNLLSK----------NAFPVNGPLS 497

  Fly   500 SMRIRGLECLVSILKCMVEWSKDLYVNPNMPVPPMQVQSPTSTEQDQADTTIQTMHSGSSHSLNS 564
            :|.|..|:.|:|:::.|.|     .|...:|...:    ||..|:.:...|::..:.|..:..
plant   498 AMHILALDGLISMVQGMAE-----RVGEELPASDV----PTHEERYEEFWTVRCENYGDPNFW-- 551

  Fly   565 NQEQLQDLPEALEERKMRKEVMETGIELFNRKPQKGVQFLQEKQLLGA-------------TCGD 616
                   :|...:.:.::|::| .|.:.|||.|.||:|:||...||..             |||
plant   552 -------VPFVRKVKHIKKKLM-LGADRFNRDPNKGLQYLQGVHLLPEKLDPKSVACFFRYTCG- 607

  Fly   617 IARWLHEDERLDKTVIGNYIGENDDHSKEVMCAYIDAFDFRQMEVVAALRFLLEGFRLPGEAQKI 681
                      |||.|:|:::|.:|....:|:..:...|||:.|.:..|||..:..|:|.||||||
plant   608 ----------LDKNVMGDFLGNHDQFCIQVLHEFAKTFDFQNMNLATALRLFVGTFKLSGEAQKI 662

  Fly   682 DRLMEKFASRYCECNPKNQLFQSADTVYVLAFSIIMLTTDLHSPQVKHKMTKEQYIKMNRGISDS 746
            .|::|.|:.||.|.:|  .:....|..:|||:|||:|.||.|:.|||.:||:|.:|:.||.|:..
plant   663 HRVLEAFSERYYEQSP--HILIDKDAAFVLAYSIILLNTDQHNAQVKTRMTEEDFIRNNRTINGG 725

  Fly   747 KSDLPEEYLSSIYDEISEHEIKMKNNSGMLQQAKPTGKQAFITEKRRKLLWNMEMEVISLTATNL 811
             :|||.||||.||..|...||:|..:.|       ||.|.                   :||:..
plant   726 -ADLPREYLSEIYHSIRHSEIQMDEDKG-------TGFQL-------------------MTASRW 763

  Fly   812 MQSV--SHVKSPF---TSAKHLEHVRPMFKMAWTPFLAAFSVGLQDCDDPEIATLCLDGIRCAIR 871
            :..:  |...||:   .:|.||:  |.||.:...|.:||.||..:..:..::...|:||:....:
plant   764 ISVIYKSKETSPYIQCDAASHLD--RDMFYIVSGPTIAATSVVFEQAEQEDVLRRCIDGLLAIAK 826

  Fly   872 IACIFHMSLERDAYVQALARFT----LLNANSPI----NEMKAKNIDTIKTLIMVAHTDGNYLGS 928
            ::..:|::...|..|.:|.:||    .|:|:..:    .:.:|:.  ..:.:.::|:..|:|:.:
plant   827 LSAYYHLNSVLDDLVVSLCKFTPFFAPLSADEAVLVLGEDARARM--ATEAVFLIANKYGDYISA 889

  Fly   929 SWLDIVKCISQLELAQLIGTGVR------PQFLSGAQTTLKDSLNP--------------SVKEH 973
            .|.:|::|:..|....::...:.      |:..:......|.|.||              .....
plant   890 GWKNILECVLSLNKLHILPDHIASDAADDPELSTSNLEQEKPSANPVPVVSQSQPSAMPRKSSSF 954

  Fly   974 IG---------ETS---SQSVVVA------------VDRIFTGSMRLDGDAIVDFVKALCQVS-V 1013
            ||         ||.   |:..:.|            :|.||:.|..|..:::...|.:|.:.| .
plant   955 IGRFLLSFDSEETKPLPSEEELAAYKHARGIVKDCHIDSIFSDSKFLQAESLQQLVNSLIRASGK 1019

  Fly  1014 DELQQQQPRMFSLQKIVEISYYNMERIRLQWSRIWQ-VLG-EHFNAVGCNSNEEISFFALDSLRQ 1076
            ||...    :|.|:.::.::..|.:||.|.|..::: :|| .......|...|:..|..|...::
plant  1020 DEASS----VFCLELLIAVTLNNRDRILLIWPTVYEHILGIVQLTLTPCTLVEKAVFGVLKICQR 1080

  Fly  1077 LSMKFMEKGEFSNFRFQKDFLRPFEHIMKKNA--SPAIRDMVVRCIAQMVNSQAHNIRS--GWKN 1137
            | :.:.|       ....:.|:..:.::|..|  :.|..:.:.:.:.::|.:.|.::||  ||:.
plant  1081 L-LPYKE-------NLTDELLKSLQLVLKLKAKVADAYCERIAQEVVRLVKANASHVRSRTGWRT 1137

  Fly  1138 IFSIFHLAAGDNEEPIVELAFQTTGKIIGD---LYKRQFAIMVDSFQDAVKCLSEFATARF--PD 1197
            |.|:..:.|...|..  |..|:....|:.:   |....:.:.:|:       .|.||.:|.  .|
plant  1138 IISLLSITARHPEAS--EAGFEALRFIMSEGAHLLPSNYELCLDA-------ASHFAESRVGEVD 1193

  Fly  1198 TSMEAIRLVRTCAQCVHEAPQLFAEHAGMENDASVAEEDRVWVRGWFPMLFSLSCVVNRCKLDVR 1262
            .|:.||.|:.....|:....|......| |.||.:...:.:. :.|..::.:|..|....:.:||
plant  1194 RSISAIDLMSNSVFCLARWSQEAKNSIG-ETDAMMKLSEDIG-KMWLKLVKNLKKVCLDQRDEVR 1256

  Fly  1263 TRALTVLFEIVKTYGESF--KPHWWKDLFNVIFRIFDNMKLPEHVTEKSEWMTTTCNHALYAIID 1325
            ..|:::|...:.......  :|.|::...:.:|.:.|:: |...:....:.:..|....|
plant  1257 NHAISMLQRAIAGADGIMLPQPLWFQCFDSAVFILLDDV-LTFSIENSRKTLKKTVEETL----- 1315

  Fly  1326 VFTQYFDVLGHLLLEELFAQLHWCVQQSNEQ--LARSGTNCLENLVISNGFKFNESTWDKTCQCI 1388
                   ||...|:.:.|.|   .:|..::|  ..|.....|..|......:|.....:|..:.|
plant  1316 -------VLATKLMSKAFLQ---SLQDISQQPSFCRLWVGVLNRLETYMSTEFRGKRSEKVNELI 1370

  Fly  1389 LDIFNATL 1396
            .::...||
plant  1371 PELLKNTL 1378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec71	NP_609675.2	PLN03076	13..1580	CDD:215560	348/1503 (23%)
		DCB	30..212	CDD:292830	41/207 (20%)
		Sec7_N	312..465	CDD:289549	37/157 (24%)
		Sec7	582..767	CDD:279680	78/197 (40%)
		DUF1981	1080..1161	CDD:286414	17/84 (20%)
GNL1	NP_001318705.1	PLN03076	<352..>1295	CDD:215560	258/1038 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815698at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820