DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sec71 and cyth2

DIOPT Version :9

Sequence 1:	NP_609675.2	Gene:	Sec71 / 34785	FlyBaseID:	FBgn0028538	Length:	1653	Species:	Drosophila melanogaster
Sequence 2:	XP_005157903.1	Gene:	cyth2 / 569358	ZFINID:	ZDB-GENE-100921-55	Length:	416	Species:	Danio rerio

Alignment Length:	223	Identity:	105/223 - (47%)
Similarity:	141/223 - (63%)	Gaps:	19/223 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   568 QLQDLPEALEERKMRKEVMET----------------GIELFNRKPQKGVQFLQEKQLLGATCGD 616
            ::|.|.|.|.|..:..|.:||                |.:.||..|:||:.||.|.:||..|..|
Zfish    48 EIQRLKEELREAIIEVEGLETSTEGSKTLQKSRHVAMGRKKFNMDPKKGIVFLVENELLRHTPED 112

  Fly   617 IARWLHEDERLDKTVIGNYIGENDDHSKEVMCAYIDAFDFRQMEVVAALRFLLEGFRLPGEAQKI 681
            ||::|::.|.|:||.||:|:||.||.:.:|:.|::|..:|..:.:|.|||..|..||||||||||
Zfish   113 IAQFLYKGEGLNKTAIGDYLGERDDFNIKVLQAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKI 177

  Fly   682 DRLMEKFASRYCECNPKNQLFQSADTVYVLAFSIIMLTTDLHSPQVKHKMTKEQYIKMNRGISDS 746
            ||:||.||.|||.|||  .:|||.||.|||:|:||||.|.||:|.|:.|.|.|::|.|||||:|.
Zfish   178 DRMMEAFAQRYCHCNP--GVFQSTDTCYVLSFAIIMLNTSLHNPNVRDKPTVERFISMNRGINDG 240

  Fly   747 KSDLPEEYLSSIYDEISEHEIKMKNNSG 774
             .|||||.|.::||.|.....|:..:.|
Zfish   241 -GDLPEELLRNLYDSIKNEPFKIPEDDG 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sec71	NP_609675.2	PLN03076	13..1580	CDD:215560	105/223 (47%)
		DCB	30..212	CDD:292830
		Sec7_N	312..465	CDD:289549
		Sec7	582..767	CDD:279680	98/200 (49%)
		DUF1981	1080..1161	CDD:286414
cyth2	XP_005157903.1	Sec7	78..260	CDD:279680	95/184 (52%)
		PH_GRP1-like	275..394	CDD:269954
		PH	279..392	CDD:278594
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582791
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740