Protein Alignment Sec71 and psd3l

DIOPT Version :10

• Sequence 1: NP_609675.2
• Gene: Sec71 / 34785
• FlyBaseID: FBgn0028538
• Length: 1653
• Species: Drosophila melanogaster
• Sequence 2: XP_068079995.1
• Gene: psd3l / 559329
• ZFINID: ZDB-GENE-030131-8195
• Length: 1135
• Species: Danio rerio
• Alignment Length: 1106
• Identity: 221/1106 - (19%)
• Similarity: 354/1106 - (32%)
• Gaps: 389/1106 - (35%)

  Fly    17 LEKILADKDIRRSHHSQLKKSCDSALEQIKAELISAGQIAEGNE------------LPCAALPLP 69
            |:..|.|.||   ..:.|.:..|..|..:.:.|.:..|.|...:            :||
Zfish   225 LDSTLDDDDI---DETSLFQEIDRELSNLLSGLTARSQHAATEQGSLSGDATASPMIPC------ 280

  Fly    70 KNDAASIINAETYFLPFELACKSRSPRIVVTALDCLQKLIAYGHLTGSIQDSANPGHLLID---- 130
                    |.:...||.:|...::       .|| ||.  ....|||   ||.....||.|
Zfish   281 --------NGQNQTLPSQLEMANQ-------GLD-LQN--GQSELTG---DSLLTSGLLFDSWCE 324

  Fly   131 ---------RIVVTIYGCFSGPQTDEAVQLQIIKALLTVVTSQHVEIHEFTLLQAVRTCYDIYLS 186
                     ........|||.....:.:......|...|..|..|                  ||
Zfish   325 ALIKDPSSVMAAANELSCFSTGNAPDKLDASPTPAGAHVEPSGEV------------------LS 371

  Fly   187 SKNLVNQTTARAT--------------------------LTQMLNVIFARMENQVYELPPPN--- 222
            .:|...:|..:.|                          |.::..:....:|.......||.
Zfish   372 QENSGKETEGKRTGSPSPIRTDEPSAEIVDESLEESNKILAEVPGIFSGFLEGGKLRDKPPKKLR 436

  Fly   223 --SNPTNGSIHSEDCNGSGEESLRDSDEVIASELLAEIISAAYNEAMKDQESVGEPE--PTLNGN 283
              .:.....::.|..|||.:..      .:..|:..:|.|.|  .|...|.||..||  ||.||.
Zfish   437 FVESRAESLVNGEMQNGSHQSC------SVKEEVTQDIQSTA--AAGVPQGSVLRPEQKPTENGT 493

  Fly   284 DYSSHSDHDSVELHSENDAVVTAKFTHILQKDAF--LVFRALCKLSMKPLPDGHPDPKSHELRSK 346
            |..|.....:.|:.:.:  |.:.:|.:||:.:..  .::.::..|.....|...|.|:|....|.
Zfish   494 DRCSAGKSAAGEIDTTD--VFSCQFENILESERLRGTLYSSMDSLDALSNPVPEPTPQSTLEPSF 556

  Fly   347 VLSLHLLLLILQNAGPVFRSNEMFIMAIKQYLCVALSNNGVSLVPEVFELSLSIFVALLSNFKVH 411
            ...:.|..:|.|.                      |.:..:.|.|...:||....|..:::.|..
Zfish   557 AFDIPLTPMIQQR----------------------LKDRSLFLEPAAPDLSSDTEVLSVTSTKER 599

  Fly   412 LKRQIEVFFKEIFLNILEANSSSFEHKWMVIQALTRICADAQSVVDIYVNYDCDFSAANLFERLV 476
            .|..:||             :|||         |:..|.|:           |...|..|.||
Zfish   600 GKTALEV-------------TSSF---------LSAGCKDS-----------CAALANGLNER-- 629

  Fly   477 NDLSKIAQGRQALELGANPMQEKSMRIRGLECLVS---ILKCMVEWSKDLYVNPNMPVPPMQVQS 538
             |.....||                      ||.|   :...:.:|..|:.|          |:.
Zfish   630 -DPKDWLQG----------------------CLSSDAGLKDVLSDWDSDMDV----------VEC 661

  Fly   539 PTSTEQDQADTTIQTMHSGSSHSLNSNQEQLQDLPEALEERKMRKEVMETGIELFNRKPQKGVQF 603
            ...|:         .:|:||    .|:||..:.|
Zfish   662 LKDTD---------VLHNGS----RSDQEAARRL------------------------------- 682

  Fly   604 LQEKQLLGATCGDIARWLHEDERLDKTVIGNYIGENDDHSKEVMCAYIDAFDFRQMEVVAALRFL 668
                          ||.|:..|...::.:..::|:|:|.||.|...|:..|:|....:..:||..
Zfish   683 --------------ARRLYHLEGFRRSDVAKHLGKNNDFSKMVAEEYLTFFEFTDQTLDQSLRCF 733

  Fly   669 LEGFRLPGEAQKIDRLMEKFASRYCECNPKNQLFQSADTVYVLAFSIIMLTTDLHSPQVKHKMTK 733
            |:.|.|.||.|:.:|::..|::||.:|||  .:..:.|.|:.|..::::|.||||.|.:..|||.
Zfish   734 LKAFSLMGETQERERVLIHFSNRYYQCNP--TIITAQDGVHCLTCALMLLNTDLHGPNIGKKMTC 796

  Fly   734 EQYIKMNRGISDSKSDLPEEYLSSIYDEISEHEIKMKNNSGMLQQAKPTGKQAFITEKRRKLLWN 798
            :::|....|::..: |.|.|.|.|:|:.|                            |..||.|.
Zfish   797 QEFINNLDGLNGGQ-DFPRELLKSLYNSI----------------------------KNEKLEWA 832

  Fly   799 MEMEVISLTATNL--------MQSVSHVKS---PFTSAKHLEHV--------------------R 832
            ::.:.:..:.:.|        .:|:|.:.|   ||....|..:.                    .
Zfish   833 VDGDELKKSLSELADKNHHSHSKSISRISSGSNPFLDIAHDPNAAVYKTGFLARKIHADMDGKKT 897

  Fly   833 PMFKMAWTPFLAAFSVGL-----QDCDDPEIATLCLDGIRCAIRI---ACIFHMSLERDAYVQAL 889
            |..|..|..|.|... |:     :|...||.| |..|.::.||.:   ..|..|..|:...|..|
Zfish   898 PRGKRGWKTFYAVLK-GMILYLQKDEYKPEKA-LSEDDLKNAISVHHALAIKAMDYEKKPNVLKL 960

  Fly   890 A----RFTLLNANSPINEMKAKNIDTIKTLIMVAHTDGNYLGSSWLDIVKCISQLELAQLIGTGV 950
            .    |..|..|.|| .||:                       ||:.|:..::.:..|
Zfish   961 KTADWRVFLFQAQSP-EEME-----------------------SWIRIINSVAAMFSA------- 994

  Fly   951 RPQFLS--GAQ----------TTLKDSLNPSVKEHIGETSSQSVVVAVDRIFTGSMRLDGDAIVD 1003
             |.|.:  |:|          ||.:.|....:|.|..:....|..:|..|.:....::....|.:
Zfish   995 -PSFPAAIGSQKKFSRPLLPATTTRMSQEEQLKSHEAKLKHVSTELAEHRSYPPDKKVKAKEIDE 1058

  Fly  1004 F 1004
            :
Zfish  1059 Y 1059

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec71	NP_609675.2	PLN03076	13..1580	CDD:215560	221/1106 (20%)
psd3l	XP_068079995.1	Sec7	675..829	CDD:238100	53/229 (23%)
		PH_EFA6	873..998	CDD:270107	31/158 (20%)