Protein Alignment Sec71 and psd2

DIOPT Version :9

• Sequence 1: NP_609675.2
• Gene: Sec71 / 34785
• FlyBaseID: FBgn0028538
• Length: 1653
• Species: Drosophila melanogaster
• Sequence 2: XP_021336783.1
• Gene: psd2 / 557199
• ZFINID: ZDB-GENE-030131-3033
• Length: 838
• Species: Danio rerio
• Alignment Length: 1061
• Identity: 202/1061 - (19%)
• Similarity: 355/1061 - (33%)
• Gaps: 369/1061 - (34%)

  Fly   212 ENQVYELPPPNSNPTNGSIHSEDCNGSGEESLRDSDEVIASELLAEIISAAYNEAMKDQESVGEP 276
            |.|...|..|...|.....|.|:|||:..|:....|.           ....|...:::|...|.
Zfish     4 EGQDDPLHTPAETPEGQEEHLENCNGTETETEEPDDG-----------DTENNRNTEEEEEEEEE 57

  Fly   277 EPTLNGND-YSSHSDHDSVELHSENDAVVTAKFTHILQKDAFLVFRALCKLSMKPLPDGHPDPKS 340
            :.||:.:| .:...:...::..:||..:.....|...:||:.:   .:|.|..:   :|..|...
Zfish    58 KVTLDQDDGRNGEIESSCLDPGTENGDICEGGDTQRAEKDSSV---TICSLRFE---NGTEDDSE 116

  Fly   341 HELRSKVLSLHLLLLILQNAGPVFRSNEMFIMAIKQYLCVALSNNGVSLVPEVFELSLSIFVALL 405
            .:...:|:.                                 ....:......||||:....|.:
Zfish   117 EQDDEEVIP---------------------------------HEGNLDAFSSTFELSVEEADAEV 148

  Fly   406 SNFKVHLKRQIEVFFKEIFLNILEANSSSFEHKWMVIQALTRICA--------DAQSVVDIYVNY 462
            .:.:   :.:.|...::.|       ||:||   .:::.:.:...        :.:...|.....
Zfish   149 EDEE---REETETRNQDSF-------SSTFE---SIVERVAKATVVEEEEEEEEGEEEFDRTKES 200

  Fly   463 DCDFSAANLFERLVNDLSKIAQGRQALELGANPMQEKSMRIRGLECLVS-----ILKCMVEWSKD 522
            ...||:.  |||:|                      :|..:||..|..|     :|....|  .|
Zfish   201 QDGFSST--FERIV----------------------ESELLRGGTCYSSLDSLDVLSLTDE--TD 239

  Fly   523 LYVNPNMPVPPMQVQSP-------------------------TSTEQDQAD------TTIQ---- 552
            ..|:...|:.|:..|..                         |.|.:|:|.      |||.
Zfish   240 SCVSFEAPLTPLIQQRALMGPEPPELELETVQEGAEGEGEFGTETARDEASSASPLRTTIPGSRS 304

  Fly   553 ----------TMHSGSSHSLNSNQEQLQDLPEALEERKMRKEVMETGIELFNRKPQKGVQFLQEK 607
                      ::.:|....|..|.:....:|.::.:..:...:.::..||      ..|..|:.
Zfish   305 ENVLSQPAQWSIPNGFHIELPGNGQSAGMMPNSISDANLTDVLCDSDSEL------GSVDTLER- 362

  Fly   608 QLLGAT------C---GDIAR-------WLHEDERLDKTVIGNYIGENDDHSKEVMCAYIDAFDF 656
               |:|      |   .|.|:       :|...:|.|   :..::|:|::.|:.|...|:..|||
Zfish   363 ---GSTDTLANGCRVDADAAKRLAKRLFYLEGFKRCD---VARHLGKNNEFSQLVASEYLSFFDF 421

  Fly   657 RQMEVVAALRFLLEGFRLPGEAQKIDRLMEKFASRYCECNPKNQLFQSADTVYVLAFSIIMLTTD 721
            ..:.:..|||..|:.|.|.||.|:.:|::..|:.|:|.|||  :...|.|..:.|..::::|.||
Zfish   422 TGLSLDRALRNFLKAFPLMGETQERERVLVHFSKRFCHCNP--ETLTSEDGAHTLTCALMLLNTD 484

  Fly   722 LHS-PQVKHKMTKEQYIKMNRGISDSKSDLPEEYLSSIYDEISEHEIKMKNNSGMLQQAKPTGKQ 785
            ||. ..:..||:.:|:|....|:.|.| |.|:|.|..:|:.|
Zfish   485 LHGHVNIGKKMSCQQFISNLDGLDDGK-DFPKELLKVLYNSI----------------------- 525

  Fly   786 AFITEKRRKLLWNMEMEVISLTATNLMQS-----------VSHVKSPF---------TSAKHLEH 830
                 |..||.|.:|.|.:..:.:.|::.           |:...:||         |:.||...
Zfish   526 -----KNEKLEWAIEEEELRKSLSELVEEQCEAGGKRVVRVTDGSNPFIGIPLLLNATTYKHGVL 585

  Fly   831 VR-----------PMFKMAWTPFLAAFS---VGLQ------DCDDPEIATLCLDGIRCAIRIACI 875
            .|           |..:..|..|.|...   :.||      |.|..|:      .::.|:|:
Zfish   586 TRKSHADMDGKRTPRGRRGWKKFYAVLKGMILYLQKDEYKPDKDLSEV------DLKNAVRV--- 641

  Fly   876 FHMSLERDAYVQALARFTLLNANSPINEMKAKNIDTIKT-----LIMVAHTDGNYLGSSWLDIVK 935
             |.:|                |....:..|.:|:..:||     .::.|.::...:  ||:..:.
Zfish   642 -HHAL----------------ATRACDYSKRQNVLKLKTSDWRVFLLQAPSEEEMM--SWIFRIN 687

  Fly   936 CISQLELAQLIGTGV-------RPQFLSGAQTTLKDSLNPSVKEHIGETSSQSVVVAVDRIFTGS 993
            .::.|..|......:       || .|..:.|.|..  ...:|.|..:
Zfish   688 LVAALFSAPAFPAAIGSMKKFCRP-LLPSSTTRLNQ--EEQLKSHENK----------------- 732

  Fly   994 MRLDGDAIVDFVKALCQVSV--DELQQQQPRMFSLQKIVEISYYNMERIRLQWSRIWQVLGEHFN 1056
                          |.||||  :|.::..|.:....|       ..|..|::         ||:
Zfish   733 --------------LKQVSVELEEHKRSPPELTPKSK-------ESEEYRIK---------EHY- 766

  Fly  1057 AVGCNSNEEISFFALDSLRQLSMKF----MEKGEFSNFRFQ-KDFLRPFEHIMKKNASPAIRDMV 1116
                .:.|:..:....||.|..::.    ::|.|.|.|..: |:     .|:.|..:||:|..
Zfish   767 ----LTYEKCRYETYISLLQAKIRAGSDDLDKIEASLFSGEAKE-----GHLRKTQSSPSISQ-- 820

  Fly  1117 VRCIAQMVNSQA-------HN 1130
                .|.||.:|       ||
Zfish   821 ----GQGVNGRAAHKHIPEHN 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec71	NP_609675.2	PLN03076	13..1580	CDD:215560	202/1061 (19%)
		DCB	30..212	CDD:292830	202/1061 (19%)
		Sec7_N	312..465	CDD:289549	19/160 (12%)
		Sec7	582..767	CDD:279680	57/201 (28%)
		DUF1981	1080..1161	CDD:286414	16/63 (25%)
psd2	XP_021336783.1	Sec7	361..530	CDD:238100	54/206 (26%)
		PH_EFA6	576..699	CDD:270107	27/150 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582826
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840