Protein Alignment Sec71 and iqsec3b

DIOPT Version :10

• Sequence 1: NP_609675.2
• Gene: Sec71 / 34785
• FlyBaseID: FBgn0028538
• Length: 1653
• Species: Drosophila melanogaster
• Sequence 2: XP_682922.4
• Gene: iqsec3b / 555340
• ZFINID: ZDB-GENE-050420-210
• Length: 1051
• Species: Danio rerio
• Alignment Length: 517
• Identity: 130/517 - (25%)
• Similarity: 226/517 - (43%)
• Gaps: 126/517 - (24%)

  Fly   526 NPNMPVPPMQVQSPTSTE-QDQADTTIQTMHSG-------------------------SSHSLNS 564
            :|..|.||     |:..| ::|....:.|:.:|                         ||.|.::
Zfish   443 DPEFPPPP-----PSEEEKENQQPIGLDTVTTGAGLEGKQTNQVAPEIAENSSDPISSSSTSTSA 502

  Fly   565 NQEQLQDLPE---------ALEERKMRKEVMETGIELFNRKPQKGVQFLQEKQLLGATCGDIARW 620
            .:..:..||.         .|.....||.:...|:.|||..|.||:|||..:..:..|...:|.:
Zfish   503 CETMILSLPRPHCQNTPCGTLSTDIARKRLYRIGLNLFNVNPDKGIQFLISRGFIPDTAIGVAHF 567

  Fly   621 LHEDERLDKTVIGNYIGEND-DHSKEVMCAYIDAFDFRQMEVVAALRFLLEGFRLPGEAQKIDRL 684
            |.:.:.|.:.:||.::|.:. ..:::|:...:|..||..:|:..|||......|:.|||||::||
Zfish   568 LLQRKGLSRQMIGEFLGNSKRQFNRDVLDCVVDEMDFSMLELDEALRKFQAHVRVQGEAQKVERL 632

  Fly   685 MEKFASRYCECNPK-NQLFQSADTVYVLAFSIIMLTTDLHSPQVK--HKMTKEQYIKMNRGISDS 746
            :|.|:.|||.|||. .|.|.:.||:::|||:|::|.||::||.:|  .||..|.:|:..||:.|.
Zfish   633 IEAFSQRYCMCNPDVVQQFHNPDTIFILAFAIVLLNTDMYSPNIKPERKMLLEDFIRNLRGVDDG 697

  Fly   747 KSDLPEEYLSSIYDEISEHEIKMKNNSGMLQQAKPTGKQAFITEKRRKLLWNMEMEVI------S 805
             :|:|.|.|:.||:.|.:.|::...:           ...::|...:.:|   .|:.|      .
Zfish   698 -ADIPREMLAGIYERIQQRELRSNED-----------HVTYVTRVEQSIL---GMKTILSVPHRR 747

  Fly   806 LTATNLMQSVSHVKSPFTSAKHLEHVRPMFKMAWTPFLAAFS---VGLQDCDDPEIA---TLC-- 862
            |...:.:..|:.|..|...|.|...|          ||  |:   |.|:.|...:.|   |.|
Zfish   748 LVCCSRLYEVTDVNKPQKQASHQREV----------FL--FNDLIVILKLCPKKKTAATYTFCKA 800

  Fly   863 --LDGIRCAIRIACIFHMSLERDAYVQALARFTLLNANSPINEMKAKNIDTIKTLIMVAHTDGNY 925
              |.|::        ||: .|.:.|...:   |:|   ||.:..|.:.:              ::
Zfish   801 MGLLGMQ--------FHL-FENEYYPHGI---TIL---SPFSSEKKQVV--------------SF 836

  Fly   926 LGSSWLDIVKCISQL-----ELAQLIGTGVRPQFLSGAQTTLKDSLNPSVKE---HIGETSS 979
            ...|..:::|.|..|     |:|::  ..:|.::....|..:::..|.:..:   |.|.:|:
Zfish   837 CSQSADELLKFIEDLRESIAEVAEM--EQIRIEWELERQQVVRNQTNKNGTQLDIHAGPSSA 896

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec71	NP_609675.2	PLN03076	13..1580	CDD:215560	130/517 (25%)
iqsec3b	XP_682922.4	Sec7	529..717	CDD:460178	71/188 (38%)
		IQ_SEC7_PH	739..867	CDD:465120	35/170 (21%)