DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sec71 and Fbxo8

DIOPT Version :9

Sequence 1:	NP_609675.2	Gene:	Sec71 / 34785	FlyBaseID:	FBgn0028538	Length:	1653	Species:	Drosophila melanogaster
Sequence 2:	NP_056606.2	Gene:	Fbxo8 / 50753	MGIID:	1354696	Length:	319	Species:	Mus musculus

Alignment Length:	193	Identity:	57/193 - (29%)
Similarity:	102/193 - (52%)	Gaps:	11/193 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   573 PEALEERKMRKEVMETGIELFNRKPQKGVQFLQEKQLLGATCGDIARWLHEDERLDKTVIGNYIG 637
            |.....||:..: ::.|...||..|::||.:...|.:|..:..:||:::.....|:...:..|:
Mouse   127 PLGFSFRKLYMQ-LDEGSLTFNANPEEGVSYFMSKGILDDSPKEIAKFIFCTRTLNWKKLRIYL- 189

  Fly   638 ENDDHSKEVMCAYIDAFDFRQMEVVAALRFLLEGFRLPGE-AQKIDRLMEKFASRYCECNP--KN 699
               |..::|:...:...:||...:..|||........|.| .:.::.|:.||:.|:|.|||  ..
Mouse   190 ---DERRDVLDDLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMR 251

  Fly   700 QLFQSADTVYVLAFSIIMLTTDLHSPQVKHKMTKEQYIKMNRGISDSKSDLPEEYLSSIYDEI 762
            :|..|.|.||||.:|:|:|:.||.||.||:||:|.::|:..|   .:..::.|:::..:||.|
Mouse   252 ELGLSPDAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTR---RAAQNISEDFVGHLYDNI 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sec71	NP_609675.2	PLN03076	13..1580	CDD:215560	57/193 (30%)
		DCB	30..212	CDD:292830
		Sec7_N	312..465	CDD:289549
		Sec7	582..767	CDD:279680	54/184 (29%)
		DUF1981	1080..1161	CDD:286414
Fbxo8	NP_056606.2	F-box-like	74..112	CDD:372399
Fbxo8	NP_056606.2	Sec7	133..312	CDD:238100	56/187 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815698at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820