Protein Alignment Sec71 and Psd3

DIOPT Version :10

• Sequence 1: NP_609675.2
• Gene: Sec71 / 34785
• FlyBaseID: FBgn0028538
• Length: 1653
• Species: Drosophila melanogaster
• Sequence 2: XP_006253101.1
• Gene: Psd3 / 306380
• RGDID: 1559968
• Length: 1296
• Species: Rattus norvegicus
• Alignment Length: 689
• Identity: 140/689 - (20%)
• Similarity: 265/689 - (38%)
• Gaps: 164/689 - (23%)

  Fly   405 LSNFKVHLKRQIEV------FFKE-----------IFLNILEANSSSFEHKWMVIQALTRICADA 452
            |...|.||:...::      |||:           :.....|.::..:..::..|...|.:...|
  Rat   639 LRESKEHLEENFDIQGDKERFFKQEEHLRGGDDDILGPGYTEDSTDVYSSQFETILDNTSLYYSA 703

  Fly   453 QSVVDIYVNYDCDFSAANLFERLVNDL--SKIAQGRQALELGANPMQEKSMRIRGLECLVSILK- 514
            :|:..:|...|..||    ||..:..:  .:|.:|.|.||         ...:.|...::|:..
  Rat   704 ESLETLYSEPDSYFS----FEMPLTPMIQQRIKEGGQFLE---------RTSVGGHHDVLSVSAD 755

  Fly   515 --CMVEWSKDLYVNPNMPVPPMQVQSPTSTEQDQA--DTTIQTMHSGSSHSLNSNQEQLQDLPEA 575
              .::.:|..:....:.|...:..:.|    |:.|  .::......|....|:.|.|  ....|.
  Rat   756 GGIVMGYSTGITNGLHDPSNSVYTRGP----QEIAFWGSSGYCFDKGKPTRLDGNSE--MGSTEI 814

  Fly   576 LEERKMRKEVME-------TGIELFNRKPQKGVQFLQEKQLLGATCGDIARWLHEDERLDKTVIG 633
            ||     ||..|       :.:|...|                     :|:.|:..:|..::.:.
  Rat   815 LE-----KETTENLSNGTNSNVEAAKR---------------------LAKRLYHLDRFKRSDVA 853

  Fly   634 NYIGENDDHSKEVMCAYIDAFDFRQMEVVAALRFLLEGFRLPGEAQKIDRLMEKFASRYCECNPK 698
            .::|:|::.||.|...|:..|||..|.:..:||:.|:.|.|.||.|:.:|::..|::||..|||
  Rat   854 KHLGKNNEFSKLVAEEYLKFFDFTGMTLDQSLRYFLKAFSLVGETQERERILIHFSNRYFSCNP- 917

  Fly   699 NQLFQSADTVYVLAFSIIMLTTDLHSPQVKHKMTKEQYIKMNRGISDSKSDLPEEYLSSIYDEIS 763
             ....|.|.|:.|..::::|.||||...:..|||.:::|...:|:::. .|..::.|.::|:.|.
  Rat   918 -DTITSKDGVHCLTCALMLLNTDLHGHNIGKKMTCQEFITNLQGVNEG-GDFSKDLLKALYNSIK 980

  Fly   764 EHEIKMKNNSGMLQQAKPTGKQAFITEKRRKLLWNMEMEVISLTATNLMQSVSH------VKSPF 822
            ..:::...:....:::...|     |:::........:..|..| ||....:.|      .||.|
  Rat   981 NEKLEWAADDEEKKKSPSEG-----TDEKANGTHPKTISRIGST-TNPFLDIPHDPNAAVYKSGF 1039

  Fly   823 TSAK-HLE---HVRPMFKMAWTPFLAAFSVGLQDCDDPEIATLCLDGIRCAIRIACIFHMSLERD 883
            .:.| |.:   ...|..|..|..|.|...           .|:                :.|::|
  Rat  1040 LARKIHADMDGKKTPRGKRGWKTFYAVLK-----------GTV----------------LYLQKD 1077

  Fly   884 AY--VQALARFTLLNANSPINEMKAK--------NIDTIKTL---IMVAHTDGNYLGSSWLDIVK 935
            .|  .::|:...|.||.|..:.:.:|        |:..:||.   :::..|........|::.:.
  Rat  1078 EYKPEKSLSDEDLKNAVSVHHALASKATEYEKKPNVFKLKTADWRVLLFQTQSPEEMQGWINKIN 1142

  Fly   936 CISQLELAQLIGTGVRPQFLS--GAQ----------TTLKDSLNPSVKEHIGETSSQSVVVAVDR 988
            |::.:..|        |.|.:  |:|          ||.|.|....:|.|..:....:..:|..|
  Rat  1143 CVAAVFSA--------PPFPAAIGSQKKFSRPLLPATTTKLSQEEQLKSHESKLKQITTELAEHR 1199

  Fly   989 IFTGSMRLDG---------DAIVDFVKALCQVSVDELQQ 1018
            .:....::..         |..:||.|...::.|..|::
  Rat  1200 SYPPDKKVKAKDVDEYKLKDHYLDFEKTRYEIYVSILKE 1238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec71	NP_609675.2	PLN03076	13..1580	CDD:215560	140/689 (20%)
Psd3	XP_006253101.1	Sec7	830..984	CDD:238100	48/177 (27%)
		PH_EFA6	1029..1154	CDD:270107	28/159 (18%)