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Protein Alignment Sec71 and Psd4

DIOPT Version :9

Sequence 1:	NP_609675.2	Gene:	Sec71 / 34785	FlyBaseID:	FBgn0028538	Length:	1653	Species:	Drosophila melanogaster
Sequence 2:	NP_001342160.1	Gene:	Psd4 / 215632	MGIID:	2674093	Length:	1005	Species:	Mus musculus

Alignment Length:	738	Identity:	146/738 - (19%)
Similarity:	259/738 - (35%)	Gaps:	210/738 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 MENQVYELPPPNSNPTNGSIHSEDCNGSGEESLRDSDEVI--ASELLAEIISAAYNEAMKDQE-- 271
            :||.:.::....::.:..|:......||.:::...|.:|:  |..|.|::......|.::..|
Mouse    70 LENCLVQVQARQASASLRSLEDNSSLGSPQQNQSSSTQVVFWAGILQAQMCVLDLEEELEKTEGL 134

  Fly   272 ---------------------SVGEPEPTLNGNDYSSHSDHD------------SVELHSENDAV 303
                                 |...||...:..|.||..:.:            |:|..:|.|::
Mouse   135 RAELRCCIPPPSKDLLGDEGLSPSRPEEDEDSGDDSSGPEEENQTWPREKIPGSSLEWGAEEDSI 199

  Fly   304 VTAKFTHILQKDAFLVFRALCKLSMKP-------LPDGHPDPKSHELRSKVLSLHLLLLILQNAG 361
            ..         |..|...:.|..:...       .|:.|||.|:.....:.|...     ||...
Mouse   200 FF---------DNPLFLESPCSDTSTEGECFSWGYPNSHPDMKTWHQSPQTLDSP-----LQKGT 250

  Fly   362 PVFR-SNEMF-----------------IMAIKQYLCVAL-SNNGVSLVPEVFELSLSIFVALLSN 407
            .::| .||:.                 :.:.|.:.|:|| |..|...||...|...|.
Mouse   251 GLWRQENELDLGSDTADHGGCSTPPFPVPSYKMHPCLALGSTEGDPTVPPDQEGETSC------- 308

  Fly   408 FKVHLKRQIEVFFKEIFLNILEANSSSFEHKWMVIQALTRICADAQSVVDIYVNYDCDF------ 466
                          |..|......:...:|:  :||.     :|         |::.|.
Mouse   309 --------------EDDLGHGSPKAPFVDHE--LIQE-----SD---------NFEFDLRPATTH 343

  Fly   467 -----------SAANLFERLVNDLSKIAQGRQALELGANPMQEKSMRIRGLECLVSILKC-MVEW 519
                       |.::|.:.::.||.:....|....|.:   |.:..|..|  |....:.| :..|
Mouse   344 PVQPWGSQTSQSLSDLTQPILEDLQREDPSRSQETLIS---QNRGERDAG--CFQEPVFCTLAPW 403

  Fly   520 -SKDLYVNPNMPVPPMQVQSPTSTEQDQADTTIQT-MHS-----GSSHSLNSNQEQLQDLPEALE 577
             |:...:.||.|....:...|..:.....|::.:. :||     .:||.|..::.:|..|.|...
Mouse   404 GSQTSLLEPNCPESEGRGSGPQPSPVSSQDSSPRVLLHSPKWPQDASHLLQKDRSELSSLKEEET 468

  Fly   578 ER--KMRKE------------------VMETGIELFNRKPQKGVQFLQE--------KQLLGATC 614
            |.  .:|:|                  |.....|.....|....|..:|        ::|.....
Mouse   469 EEVPSLRQEAECEDTSRSEDASANQHHVHLASAEGLPESPMPQAQSPEEGWRPSSSREKLANDIR 533

  Fly   615 GDIARW-----LHEDERLDKTVIGNYIGENDDHSKEVMCAYIDAFDFRQMEVVAALRFLLEGFRL 674
            .|...|     |::.....|:.:..::.:|:|.|:.|..||:..|.|....:..|||..|:...|
Mouse   534 NDKGAWNLALRLYQLNGFRKSEVAAHLRKNNDFSRAVAEAYLSFFQFEGQSLDRALRGFLQALVL 598

  Fly   675 PGEAQKIDRLMEKFASRYCECNPKNQLFQSADTVYVLAFSIIMLTTDLHSPQVKHKMTKEQYIKM 739
            .||.|:.:|::.:|:.|:..|||  ..|.|.|:|:.|..:|::|.||||...:...|:.::::..
Mouse   599 SGETQERERILYQFSKRFHYCNP--GAFPSVDSVHTLTCAIMLLNTDLHGQNIGKSMSCQEFVTN 661

  Fly   740 NRGISDSKSDLPEEYLSSIYDEISEHEIKM--------------------KNNSGMLQQAK---- 780
            ..|:.|.: :.|:|.|.::|..|...:::.                    |.:|..||.|:
Mouse   662 LNGLQDGR-NFPKELLKALYWSIRSEKLEWAIDEEDADRPEKDQPSPSAGKISSPFLQMAQDPTM 725

  Fly   781 PTGKQAFITEKR------RKLLW 797
            ||.||..:..|.      :|..|
Mouse   726 PTYKQGILARKMHHIADGKKTPW 748

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.