DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sec71 and cyth3b

DIOPT Version :9

Sequence 1:	NP_609675.2	Gene:	Sec71 / 34785	FlyBaseID:	FBgn0028538	Length:	1653	Species:	Drosophila melanogaster
Sequence 2:	XP_021330428.1	Gene:	cyth3b / 100537448	ZFINID:	ZDB-GENE-130530-529	Length:	396	Species:	Danio rerio

Alignment Length:	208	Identity:	101/208 - (48%)
Similarity:	141/208 - (67%)	Gaps:	5/208 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   567 EQLQDLPEALEERKMRKEVMETGIELFNRKPQKGVQFLQEKQLLGATCGDIARWLHEDERLDKTV 631
            |||..:.|:  :...|.:.:..|.:.||..|:||:|||.|..||..|..|||::|::.|.|:|||
Zfish    50 EQLTCVGES--KTTQRNKQIAMGRKKFNMDPKKGIQFLLENDLLQQTPEDIAQFLYKGEGLNKTV 112

  Fly   632 IGNYIGENDDHSKEVMCAYIDAFDFRQMEVVAALRFLLEGFRLPGEAQKIDRLMEKFASRYCECN 696
            ||:|:||.|:.:.:|:.|:::..:|..:.:|.|||..|..||||||||||||:||.||||||:||
Zfish   113 IGDYLGERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCQCN 177

  Fly   697 PKNQLFQSADTVYVLAFSIIMLTTDLHSPQVKHKMTKEQYIKMNRGISDSKSDLPEEYLSSIYDE 761
            |  .:|||.||.|||:|:||||.|.||:|.|:.|...|::|.|||||:|. .|||||.|.::|:.
Zfish   178 P--GVFQSTDTCYVLSFAIIMLNTSLHNPNVRDKPAVERFISMNRGINDG-GDLPEELLRNLYES 239

  Fly   762 ISEHEIKMKNNSG 774
            |.....|:..:.|
Zfish   240 IKSEPFKIPEDDG 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sec71	NP_609675.2	PLN03076	13..1580	CDD:215560	101/208 (49%)
		DCB	30..212	CDD:292830
		Sec7_N	312..465	CDD:289549
		Sec7	582..767	CDD:279680	95/184 (52%)
		DUF1981	1080..1161	CDD:286414
cyth3b	XP_021330428.1	Sec7	63..245	CDD:307500	95/184 (52%)
cyth3b	XP_021330428.1	PH_GRP1-like	260..379	CDD:269954
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582799
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840