Protein Alignment Sec71 and iqsec1b

DIOPT Version :10

• Sequence 1: NP_609675.2
• Gene: Sec71 / 34785
• FlyBaseID: FBgn0028538
• Length: 1653
• Species: Drosophila melanogaster
• Sequence 2: XP_005169390.3
• Gene: iqsec1b / 100148736
• ZFINID: ZDB-GENE-120813-1
• Length: 1252
• Species: Danio rerio
• Alignment Length: 507
• Identity: 136/507 - (26%)
• Similarity: 231/507 - (45%)
• Gaps: 91/507 - (17%)

  Fly   538 SPTSTEQDQADTTI--QTMHSGSSHSLNSNQEQLQDLPEALEERKMRKEVMETGIELFNRKPQKG 600
            |.:|:.....:.|:  ||.|..:.:|.:|         .|.....:||.....|:.|||:||:||
Zfish   606 SESSSRDSLREQTLSKQTYHKETRNSWDS---------PAFSNDIIRKRHYRIGLNLFNKKPEKG 661

  Fly   601 VQFLQEKQLLGATCGDIARWLHEDERLDKTVIGNYIGEND-DHSKEVMCAYIDAFDFRQMEVVAA 664
            :|:|.|:..:..|...:|.:|.:.:.|.:.:||.::|... ..:::|:...:|..||..||:..|
Zfish   662 IQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSAMELDEA 726

  Fly   665 LRFLLEGFRLPGEAQKIDRLMEKFASRYCECNP-KNQLFQSADTVYVLAFSIIMLTTDLHSPQVK 728
            ||......|:.|||||::||:|.|:.|||.||| ..:.|::.||:::|||:||:|.||::||.||
Zfish   727 LRKFQAHIRVQGEAQKVERLIEAFSQRYCICNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVK 791

  Fly   729 --HKMTKEQYIKMNRGISDSKSDLPEEYLSSIYDEISEHEIKMKNNSGMLQQAKPTGKQAFITEK 791
              .||..|.::|..||:.|.: |:|.|.|..||:.|.:.|  :|.|...:.|.:...| ..:.:|
Zfish   792 PERKMKLEDFVKNLRGVDDGE-DIPREMLVGIYERIRKRE--LKTNEDHVSQVQKVEK-LIVGKK 852

  Fly   792 RRKLLWNMEMEVISLTATNLM--QSVSHVKSPFTSAKHLEHVRPMF---------------KMAW 839
            ....|.:....|:||....|:  ..:..|..|....|...|.|.:|               |.:.
Zfish   853 PIGSLHHGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFLFNDLLVVTKIFQKKKNSV 917

  Fly   840 T-PFLAAFSV-GLQDCDDPEIATLCLDGIRCAIRIACIFHMSLERDAYVQALARFT--------- 893
            | .|..:||: |:|                          :.|..:.|.....|.|
Zfish   918 TYSFRQSFSLYGMQ--------------------------VLLFENQYYPNGVRLTSALPGADIK 956

  Fly   894 -LLNANSPINEMKAKNIDTIKTLIMVAHTDGNYLGSSWLDIVKCISQLELAQLIGTGVRPQFLSG 957
             |:|.|:|..:.:.|..|.::..|........|...|.|:..|.:.:..::|  .:|::.:..:|
Zfish   957 VLINFNAPNPQDRKKFTDDLRESIAEVQEMEKYRIESELEKQKGVVRPSISQ--SSGLKKETGNG 1019

  Fly   958 --AQTTLKDS-----------LNPSVKE--HIGETSSQSVVVAVDRIFTGSM 994
              ::|:|.||           |:.|:::  ..|:...:|...::|....||:
Zfish  1020 NLSRTSLDDSYAMGEGLKRSALSSSLRDLSDAGKRGRRSSAGSLDSNMEGSI 1071

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec71	NP_609675.2	PLN03076	13..1580	CDD:215560	136/507 (27%)
iqsec1b	XP_005169390.3	None