DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sec71 and fbxo8

DIOPT Version :9

Sequence 1:	NP_609675.2	Gene:	Sec71 / 34785	FlyBaseID:	FBgn0028538	Length:	1653	Species:	Drosophila melanogaster
Sequence 2:	NP_001120293.1	Gene:	fbxo8 / 100145349	XenbaseID:	XB-GENE-964650	Length:	316	Species:	Xenopus tropicalis

Alignment Length:	180	Identity:	51/180 - (28%)
Similarity:	95/180 - (52%)	Gaps:	10/180 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   586 METGIELFNRKPQKGVQFLQEKQLLGATCGDIARWLHEDERLDKTVIGNYIGENDDHSKEVMCAY 650
            ::.|...||..|..|:::...:.:|..:..:||:::.....|:...:..|:    |..::|:...
Frog   136 LDEGSLTFNANPHWGIEYFISRGILDDSAKEIAKFIFCTRTLNWKNLRLYL----DRRRDVLDEL 196

  Fly   651 IDAFDFRQMEVVAALRFLLEGFRLPGE-AQKIDRLMEKFASRYCECNP--KNQLFQSADTVYVLA 712
            :...:|....:..|||........|.| .:.::.|:.||::|:|.|||  ...|..|.|.||||.
Frog   197 VTLHNFSNQFLPNALRDFFRHIHAPEERGEYLETLITKFSNRFCACNPALARDLGLSPDAVYVLC 261

  Fly   713 FSIIMLTTDLHSPQVKHKMTKEQYIKMNRGISDSKSDLPEEYLSSIYDEI 762
            :|:|:|:.||.||.||:||:|.::|:..|   .:..::.|:::..:||.|
Frog   262 YSLILLSIDLASPHVKNKMSKREFIRNTR---RAAQNISEDFVGHLYDNI 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sec71	NP_609675.2	PLN03076	13..1580	CDD:215560	51/180 (28%)
		DCB	30..212	CDD:292830
		Sec7_N	312..465	CDD:289549
		Sec7	582..767	CDD:279680	51/180 (28%)
		DUF1981	1080..1161	CDD:286414
fbxo8	NP_001120293.1	F-box-like	71..109	CDD:372399
fbxo8	NP_001120293.1	Sec7	130..309	CDD:238100	51/180 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815698at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920