DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sec71 and cyth3a

DIOPT Version :9

Sequence 1:	NP_609675.2	Gene:	Sec71 / 34785	FlyBaseID:	FBgn0028538	Length:	1653	Species:	Drosophila melanogaster
Sequence 2:	XP_001342037.2	Gene:	cyth3a / 100002190	ZFINID:	ZDB-GENE-120612-1	Length:	396	Species:	Danio rerio

Alignment Length:	193	Identity:	95/193 - (49%)
Similarity:	134/193 - (69%)	Gaps:	3/193 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   582 RKEVMETGIELFNRKPQKGVQFLQEKQLLGATCGDIARWLHEDERLDKTVIGNYIGENDDHSKEV 646
            |.:.:..|.:.||..|:||:|||.|..||..|..|||::|::.|.|:|||||:|:||.||.:..|
Zfish    63 RSKQIAVGRKKFNMDPKKGIQFLLENDLLQHTPEDIAQFLYKGEGLNKTVIGDYLGERDDFNIRV 127

  Fly   647 MCAYIDAFDFRQMEVVAALRFLLEGFRLPGEAQKIDRLMEKFASRYCECNPKNQLFQSADTVYVL 711
            :.|:::..:|..:.:|.|||..|..||||||||||||:||.:|:|||:|||  .:|||.||.|||
Zfish   128 LQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAYAARYCQCNP--GVFQSTDTCYVL 190

  Fly   712 AFSIIMLTTDLHSPQVKHKMTKEQYIKMNRGISDSKSDLPEEYLSSIYDEISEHEIKMKNNSG 774
            :||:|||.|.||:|.|:.|.:.|::|.|||||::. .|||||.|.::|:.|.....|:..:.|
Zfish   191 SFSVIMLNTSLHNPNVRDKPSVERFISMNRGINEG-GDLPEELLRNLYESIKNEPFKIPEDDG 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sec71	NP_609675.2	PLN03076	13..1580	CDD:215560	95/193 (49%)
		DCB	30..212	CDD:292830
		Sec7_N	312..465	CDD:289549
		Sec7	582..767	CDD:279680	93/184 (51%)
		DUF1981	1080..1161	CDD:286414
cyth3a	XP_001342037.2	Sec7	63..245	CDD:279680	93/184 (51%)
		PH_GRP1-like	260..379	CDD:269954
		PH	264..377	CDD:278594
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582798
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740