DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG16863 and lin-15B

DIOPT Version :9

Sequence 1:	NP_001036361.1	Gene:	CG16863 / 34784	FlyBaseID:	FBgn0028931	Length:	661	Species:	Drosophila melanogaster
Sequence 2:	NP_510587.1	Gene:	lin-15B / 181662	WormBaseID:	WBGene00023497	Length:	1440	Species:	Caenorhabditis elegans

Alignment Length:	550	Identity:	107/550 - (19%)
Similarity:	202/550 - (36%)	Gaps:	106/550 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 PQIHAVPFAGHDNLKMEEPLPS-ESPFHKD--------IAFFVCRDRQSLQIVQGEGFQHLVKVL 216
            |.:.|.....|..|    |.|: |:..|.|        :|.|........:......|..|:|.:
Worm    41 PAVRASGILRHRTL----PAPTQETAHHLDADPKTTELMARFFISQGIPFECAHEPAFLELMKHV 101

  Fly   217 CPTYRPPSAAKLEAIICRESEAQRSKLCQQLADISTLSLSCSVHTNAESRSWMELVAHFHEG--R 279
            .|....|.....:.::.:.|.:.:.:: .....:..||::..: ...|...::....|:.|.  .
Worm   102 DPNCVIPPTNVTKKLVDKISTSSKPQV-NYTKTVGPLSVTIDI-CGDEDEKYLAFSIHYFEDLYE 164

  Fly   280 QRISRTLSVLRLPDLFTSNDLVDRMDQVCQRF---DIPKSRICCVSTRSSQLLEDAVTSFMGAHH 341
            ::.:..|..|.|.:| .||.|:..:.:....:   ::..:.|.|.:....:|:|::..    ...
Worm   165 RKNAIYLRKLLLTEL-DSNSLLTNIRRSVNSYSFSNVKFTNIVCPNEEICKLVEESAV----VKR 224

  Fly   342 HVPCFADQLNSILEEVVQRPE----IRHLRDKVRSHVQST----------LQLNPQLDSIHRPIS 392
            :..||.:.:...:.::::..|    :..||..||...|::          ||.|.:||.......
Worm   225 YNVCFYNYVTRFVADLMEIEEFSSGLTQLRTFVRYMKQNSDMYSKFRRMQLQKNAELDIPSIDSG 289

  Fly   393 VYNMLDLYLKQTLVQEPLPLSTSEVDLCQQLLDVL---------------RPLTSSM---RELSR 439
            .::...::|.:.||..     .:..:.|.: ||:|               |.|...|   ||||
Worm   290 DWHSTAIFLTRCLVWH-----DTFTEFCGK-LDILHYIDNETFNHLIYLQRLLQQCMKHCRELS- 347

  Fly   440 TPYPAASTALPIAQTLINELKQEKSAEHMVAREIRLFLVQQLEEIFERMERNLHLALASLLDPRF 504
            .|..:.|..:|...::.|.: ...|..:...:.||.......:||.....::.: .:|:||||||
Worm   348 IPNNSISQVVPAIMSIRNFI-ASNSMGYRFQKRIRDSFTTSFKEITSGPSQDRY-DIATLLDPRF 410

  Fly   505 RNIPFRSGALVAQYMTQLYDMMQAHVDSGEQAVAKHPEN----------RDHYDIWAAFKSFSHG 559
               .:|.....||....|...:   :|....:..::.:|          ...|||  ..|.|::.
Worm   411 ---AYRDTVYTAQTWRSLEKKV---IDDFVNSDLQNDKNFYQDISILNQEQRYDI--IKKEFAYY 467

  Fly   560 KQRIVNGSNGPEADDEIARYFCAGMSTLRADPFQLWEELAEAHPFLHNVAQRYLHVPATAEPADR 624
            :|  .:....||.::....::  ||.....:             ||..:|:.||..||.:..|..
Worm   468 RQ--TSFVERPEENENSNHWW--GMRQTDME-------------FLAVIAREYLASPAVSIDAGY 515

  Fly   625 LFTAEG--AAVAAQYARLIENNMENILFMA 652
            .|...|  ..:...|:   ...:||.|.:|
Worm   516 YFGNGGKFQHICHTYS---HQRLENCLALA 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
CG16863	NP_001036361.1	zf-BED	4..44	CDD:280965
lin-15B	NP_510587.1	DM3	1151..1206	CDD:128933
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1121
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D223749at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820