DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16863 and F19F10.11

DIOPT Version :9

Sequence 1:	NP_001036361.1	Gene:	CG16863 / 34784	FlyBaseID:	FBgn0028931	Length:	661	Species:	Drosophila melanogaster
Sequence 2:	NP_504955.1	Gene:	F19F10.11 / 179143	WormBaseID:	WBGene00017607	Length:	1121	Species:	Caenorhabditis elegans

Alignment Length:	754	Identity:	134/754 - (17%)
Similarity:	256/754 - (33%)	Gaps:	222/754 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 KRREQDDKLRFRKVVPFKEESSDFHSELLFKAAKDASGIIELDDQGMIKAAAEDRISTKSVGYAW 125
            |:.||:..:....:...|:|..|...:|..:.......:|.:.|..|:...     ||.|.
Worm     5 KKNEQNGGITEAALQAIKQEPLDQREQLPEEIKLKPGEMILVPDDPMLPGN-----STAST---- 60

  Fly   126 VSPEATVSRTETVGGDDIIEFEPKEELDES------------EKSPLPQIHAVPFAGHDNLKMEE 178
                :..||.|..|..|::....|.:|..|            |:|..|........| |.:|...
Worm    61 ----SNFSREELPGPSDVVRTISKNDLMMSRKTAAPSSCPPKEQSMKPSFQTEKIMG-DFVKQRR 120

  Fly   179 PLPSESPF-HKDIA----FFVCRDRQSL--QIVQGEGFQHLVKVLCP-----TYRPPSAAK---- 227
            .|...:|: .||..    .::...|.|:  ..::....::|:|.:.|     |:..|.:::
Worm   121 KLNFATPWPRKDPGPSSNSWLTEYRPSVPGNQIENSNIENLIKKVAPFYSRTTHESPHSSQTVED 185

  Fly   228 -----LEAIICRESEAQRSKLCQQLADISTL----------SLSCSV-----------HTNAESR 266
                 |:.:....|:.:|:|:..|:...|.:          |.:|.|           ..|.:..
Worm   186 FRSESLDLLYPMRSQEERAKITMQINRSSPILDNEQQVLPTSGTCEVLSQFMISQGIPFENIKDS 250

  Fly   267 SWMELVAHFHEGR-----QRISRTLSVLRLP---DLFTSN------DLV---------------- 301
            |:.:|:.||..|.     :.:.|::...|..   ||....      |||
Worm   251 SFKKLLEHFEPGSVVPTVKELERSMKFKRTQKPIDLSIHGPVSITVDLVKHFGDAEDKMYLVFSV 315

  Fly   302 -------DRMDQVCQR-------------------FDIPK------------SRICCVSTRSSQL 328
                   ||.|.|..:                   ..|.|            :||  ::.|....
Worm   316 HHFENSGDRTDAVFLKRVGYSQLNYQTIVMHIRDSMSIHKYKNLSVTNILASNRI--IAHRLEND 378

  Fly   329 LEDAVTSFMGAHHHVPCFADQLNSILEEVVQRPEIRHLRD---------KVRSHVQSTL------ 378
            :...|..::...||:..|   :.::|:.......:::||:         |:||::...|
Worm   379 VHSTVNFYICFQHHITSF---VCALLDMEPFSSRLQNLREFVRKAKSDYKMRSYMHECLNKKKKY 440

  Fly   379 ---QLNPQLDSIHRPISVYNML-------DLYLKQTLV------QEPLPLSTSEVDLCQQLLDVL 427
               .|.|..|:..:  |..|.|       .|:|...::      ...:..|.:.:|| :.:..:|
Worm   441 SDNSLPPMEDTSWQ--SKMNFLKRCLELSSLFLDTVILNYEDFGNATIITSATFIDL-KVIFKIL 502

  Fly   428 RPLTSSMRELSRTPYPAASTALPIAQTLINELKQEKSAEHMVAREIRLFLVQQLEEIFERMERNL 492
            :..:...:||| .|..:.|..:|..:: |.....:.:.......::|.......:: |.....::
Worm   503 QVCSKYSQELS-GPDSSVSQVIPAIRS-IRSCLVKVTVGKAFGEDVRKCFTDTFQD-FTAGPTSM 564

  Fly   493 HLALASLLDPRFRNIPFRSGALVAQYMTQLYDMMQAHVDS---GEQAVAKH--------PENRDH 546
            ...:|::|||||       ......|..:.:..::..:..   .::..||.        |.:|:
Worm   565 KYHIATILDPRF-------AYCETMYQNETWSAIEGQLRDAFVSKRFTAKDISQLKYTVPADRE- 621

  Fly   547 YDIWAAFKSFS---HGKQRIVNGSNGPEADDEIARYFCAGMSTLRADPFQLWE-ELAEAHPFLHN 607
                :..|.||   ...::|:..|     |.|..:           :||:.|: ...:....|..
Worm   622 ----SRIKIFSSELENYKQILKTS-----DSENFK-----------NPFKFWKVHQRKGMKSLAF 666

  Fly   608 VAQRYLHVPATAEPADRLFTAEGAAVAAQYARLIENNME 646
            :|:.||..||.|..|: .|..||:....:...:..:.:|
Worm   667 LARYYLACPAVAIDAN-YFVGEGSGSLVRACNMYRDEVE 704

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
CG16863	NP_001036361.1	zf-BED	4..44	CDD:280965
F19F10.11	NP_504955.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D223749at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010