DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG16863 and LOC105945140

DIOPT Version :9

Sequence 1:	NP_001036361.1	Gene:	CG16863 / 34784	FlyBaseID:	FBgn0028931	Length:	661	Species:	Drosophila melanogaster
Sequence 2:	XP_012813067.2	Gene:	LOC105945140 / 105945140	-ID:	-	Length:	693	Species:	Xenopus tropicalis

Alignment Length:	778	Identity:	142/778 - (18%)
Similarity:	261/778 - (33%)	Gaps:	278/778 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SRSRIWKFYDKLDRNS---------AQCQLCEKVIKTSGNTSNLMKHM-KTHPQINLFDDDVVVE 56
            ::|::||::. .|.|:         ..|::|...|..|||||||..|: |.||
Frog    21 AKSKVWKYFG-FDTNAEGCILQWKKIYCRICMAQIAYSGNTSNLSYHLEKNHP------------ 72

  Fly    57 RGIYKRREQDDKLRFRKVVPFKEESSDFHSELLFKAAKDASGIIELDDQGMIKAAAEDRISTKSV 121
                                  :|..:|                       :|:..|......:.
Frog    73 ----------------------DEFCEF-----------------------VKSNTEQMREAFAT 92

  Fly   122 GYAWVSPEATVSRT-ETVGGDDIIEFEPKEELDESEKSPLPQIHAVPFAGHDNLKMEEPLPSESP 185
            .::.:.||::.... ||:...:...||.|:.|:
Frog    93 AFSKLKPESSQQVVQETLIMKNTHSFENKKHLE-------------------------------- 125

  Fly   186 FHKDIAFFVCRDRQSLQIVQGEGFQHLVKVLCPTYRPPSAAKLEAIIC-----RESEAQRSKLCQ 245
            ....:...:|.......|:....|::|:|...|.|..|    :...||     .:..|.|..:.:
Frog   126 LTSSVISLICEGMYPASILDEPTFKNLLKTAEPRYEVP----MRKYICSRVLPEKYNAIREMVLK 186

  Fly   246 QLADISTLSLSCSVHTN-----AESRSWMELVAHF-HEGRQRI----SRTLSVLRLPD------- 293
            .|.||    |.|.:.|:     .::||::.|..:| ..|....    ||.|....:|:
Frog   187 DLNDI----LWCGISTDMWKSVTQNRSYVTLSVYFMSTGPSNCLSVNSRCLKTFEVPEENKAETI 247

  Fly   294 ---LFT------------------SNDLVDRMDQVCQRFDIPKSRICCVSTRSSQLLEDAVTSFM 337
               |:.                  |.|:|    :.|...|||..
Frog   248 TRVLYETFIEWGISAKVFGATTDFSKDIV----KACSLLDIPVD--------------------- 287

  Fly   338 GAHHHVPCFADQLNSILEEVVQRPEIRHLRDKVRSHVQSTLQLNPQLDSIHRPISVYNMLDLYLK 402
                 :||.....:..:::..|.|::..|..:.|..|:...|.:         |::|.:.:...:
Frog   288 -----MPCLGQTFDMGIQQAFQLPKLSSLLSRCRKLVEYFQQSS---------IAMYMLCEKQKQ 338

  Fly   403 Q-----------------TLV---------------------QEPLPLSTSEVDLCQQLLDVLRP 429
            |                 |||                     ...|.|..||.:..:.|:|:|:|
Frog   339 QNLFPCMLISDRVSWWGSTLVMLQRLKEQQFTIAGVLVEDSNNHHLMLEASEWNTIEGLVDLLQP 403

  Fly   430 LTSSMRELSRTPYPAASTALPIAQTLIN---ELKQEKSAEHMVAREIRLFLVQQLEEIFERM-ER 490
            .......||.:.||..|...|:...|:|   .:|:....|..:|:|:   :.:.|...:::. |.
Frog   404 FKQVAEMLSVSKYPTISMVKPLLHMLLNTSLNIKETDPKEISMAKEV---IAKVLSSTYQQTPEI 465

  Fly   491 NLHLALASLLDPRFRNIPFRSGALVAQYMTQLYDMMQAHVDSGEQAVAKHPENRDHYDIWAAFKS 555
            ::.|.:|:.||||::.:||.|....||...::.:..:..:|.|::.: |:.|           |.
Frog   466 DMFLNVATFLDPRYKKLPFLSAFERAQVENRVIEEAKCFIDKGKENI-KNEE-----------KV 518

  Fly   556 FSHGKQ----RIVNGSNGPEA--DDEIARYFCAGMST------------------------LRAD 590
            |:..::    ::.:.:..|.:  :..:|..||...|:                        |..|
Frog   519 FTISEEPPMKKMASSTPPPTSSINSMLAEIFCQSGSSEDQEEWHAQVVEELSNFKSQKVLGLNED 583

  Fly   591 PFQLWEELAEAHPFLHNVAQRYLHVPATAEPADRLFTAEGAAVAAQYARLIENNMENILFMAE 653
            |.:.|.:.....|.|..|.|:|..:..|....:|||.:....|.::..||...:::..:|:.|
Frog   584 PLKWWSDRLTLFPLLPKVLQKYWCIRPTRVFPERLFNSSANVVNSKRNRLAPAHVDEQIFLYE 646

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16863	NP_001036361.1	zf-BED	4..44	CDD:280965	17/49 (35%)
LOC105945140	XP_012813067.2	zf-BED	23..72	CDD:397159	17/49 (35%)
		DUF4413	412..514	CDD:405121	26/105 (25%)
		Dimer_Tnp_hAT	568..647	CDD:399013	18/79 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	59	1.000	Domainoid score	I10461
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	118	1.000	Inparanoid score	I4637
OMA	1	1.010	-	-		QHG46645
OrthoDB	1	1.010	-	-		D223749at2759
OrthoFinder	1	1.000	-	-		FOG0012423
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46169
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.080