DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG16863 and Zbed6

DIOPT Version :9

Sequence 1:	NP_001036361.1	Gene:	CG16863 / 34784	FlyBaseID:	FBgn0028931	Length:	661	Species:	Drosophila melanogaster
Sequence 2:	XP_038947242.1	Gene:	Zbed6 / 103693666	RGDID:	9238526	Length:	983	Species:	Rattus norvegicus

Alignment Length:	763	Identity:	169/763 - (22%)
Similarity:	271/763 - (35%)	Gaps:	196/763 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SRIWKFY--DKLDRNSAQCQLCEKVIKTSG-----NTSNLMKHMK-THP----QINLFDDDVVVE 56
            |.:|.|:  |....:.|.|.:|::.:....     .||.|.:|:: |||    ..|  .|...:.
  Rat   268 SAVWNFFYTDPQHISRAVCNICKRSVSRGRPGSHLGTSTLQRHLQATHPIHWAVAN--KDSGAIG 330

  Fly    57 RGIYKRREQDDKLRFRKVVPFKEESSDFHSELLFKAAKDASGIIELDDQGMIKAAAEDRISTKSV 121
            .|:      |:.         :.||.|..::.|.  .:.:||..:|        .|||
  Rat   331 NGL------DET---------ETESGDLLNDTLH--GEKSSGSQDL--------TAED------- 363

  Fly   122 GYAWVSPEATVSRTETVGGDDIIEFEPKEELDESEKSPLPQIHAVPFAGHDNLKMEEPLPSESPF 186
                            :...|..:..|..|::...:||      :|.|..|||...:...:.:..
  Rat   364 ----------------LSDSDDTDEPPVLEVENRSESP------IPVAEQDNLAHTQERETTTDT 406

  Fly   187 HKDIAFFVCRDRQSLQIVQG-----------------EGFQHLVKVLCPTYRPPSAAKLEAIICR 234
            |       |.|..|.||.|.                 ..||..::::.|.||.||    |.....
  Rat   407 H-------CEDAASSQISQAVIQMIVEDLHPYNYFSTPAFQRFLQIVAPDYRLPS----ETYFFT 460

  Fly   235 ESEAQ-----RSKLCQQLADIST--LSLSCSVHTNAESRSWMELVAHF---------HEGRQRIS 283
            ::..|     |.|:...|.::.:  :.|:..:.|:..|..:..:..|:         ..|.....
  Rat   461 KAVPQLYDSVREKIFLTLENVQSQKIHLTVDIWTHDPSTDYFIVTVHWVSLETASSPSNGGTPNF 525

  Fly   284 RTLSVLRL----PDLFTSNDLVDRMDQV----CQRFDIPKSRICCVSTRSSQLLEDAVTSFMGAH 340
            |..:||.:    .|...:|.|.:..||:    ...|.||.   ..||..||.::. |:..  |..
  Rat   526 RKWAVLCVTGLAKDCLITNILQELNDQIGLWLSPNFLIPS---FIVSDNSSNVVH-AIKG--GGF 584

  Fly   341 HHVPCFADQLNSILEE------------VVQRPEIRHLRDKVRS-----HVQSTLQL---NPQLD 385
            .|||||...||.::::            |..|....|....|::     ..|:..||   |.:.|
  Rat   585 THVPCFLHCLNIVIQDFFCEHKSIENMLVAARKTCHHFSHSVKARQILQEFQNDHQLPWKNLKQD 649

  Fly   386 SIHRPISVYNMLDLYLKQTL-VQEPL------PLSTSEVDLCQQLLDVLRPLTSSMRELSRTPYP 443
            .....||.:.||...|:... |...|      .|::.:..|...:.|:|:|...:.:.:| ....
  Rat   650 ETGHWISTFYMLKWLLEHCYSVHHSLGRASGVVLTSLQWTLMTYVCDILKPFEEATQRVS-VKTT 713

  Fly   444 AASTALPIAQTLINELKQEKSAEHMVAREI--RLFLVQQL------EEIFERMERNLHLALASLL 500
            ..:..|||...|:..|  ::..|....|.|  .|.||..|      :.:...|.::.|..||:||
  Rat   714 GLNQVLPIIHHLLFSL--QRLREDFQVRGITQALNLVDSLSLKLESDALLSAMLKSKHCILATLL 776

  Fly   501 DPRFRNIP---FRSGALVAQYMTQLYDMMQAHVDSGEQAV------AKHPENRDHYDIWAAFKSF 556
            ||.|:|..   |..||.:..|...|.:.:..:::|...|.      |..|..|...|   :|.|.
  Rat   777 DPCFKNSLEDFFPQGADLETYKQILAEEVCNYMESSPGACQIASSEASGPLVRLGTD---SFTSI 838

  Fly   557 SHGKQRIVNGSNGPEADDEIA----------------RYFCAGMSTLRA--DPFQLWEELAEAHP 603
            ..|....  ||....|.|.:|                .||....|.|..  ||...|:......|
  Rat   839 KEGTSSA--GSMDSSAADSVAIGSRSFLFPSAVAVVDEYFKEKYSELSGGDDPLVYWQRKVSIWP 901

  Fly   604 FLHNVAQRYLHVPATAEPADRLFTAEGAAVAAQYARLIENNMENILFM 651
            .|..||.:||..|..:..::.:||........|...:..:|:|.::|:
  Rat   902 ALTQVAIQYLSCPMCSWQSECMFTTNSHFHPKQIMNMDFDNIEQLIFL 949

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16863	NP_001036361.1	zf-BED	4..44	CDD:280965	12/47 (26%)
Zbed6	XP_038947242.1	ZnF_BED	135..182	CDD:214746
		ZnF_BED	270..316	CDD:214746	11/45 (24%)
		Dimer_Tnp_hAT	873..953	CDD:399013	20/77 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D223749at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010