Protein Alignment Eato and Abcg1

DIOPT Version :9

• Sequence 1: NP_001036360.1
• Gene: Eato / 34783
• FlyBaseID: FBgn0028539
• Length: 1597
• Species: Drosophila melanogaster
• Sequence 2: NP_445954.2
• Gene: Abcg1 / 85264
• RGDID: 620294
• Length: 666
• Species: Rattus norvegicus
• Alignment Length: 658
• Identity: 130/658 - (19%)
• Similarity: 237/658 - (36%)
• Gaps: 204/658 - (31%)

  Fly   488 NNKEITVLLGHNGAGKTTMMNMIMGLVPKDSGK----IIVCSERDVASYRHLIGFCPQHSVFMSY 548
            |:.|:..::|.:||||:|:||::.|.  :::|.    :|....||:..:|.:..:..|..:.:.:
  Rat   109 NSGELVAIMGPSGAGKSTLMNILAGY--RETGMKGAVLINGMPRDLRCFRKVSCYIMQDDMLLPH 171

  Fly   549 MTCHQHLEFFAQLRGACRSDA-RDWADEKLKKLGLSDKRNEFGKNLSGGMKRRLSLGIAIAGNTK 612
            :|..:.:...|.|:...:.:. |:...|.|..|||....|....:||||.::||::.:.:..|..
  Rat   172 LTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLPCANTRTGSLSGGQRKRLAIALELVNNPP 236

  Fly   613 IVILDEPSSGLDINSRRELWDILLNLRKEKAVLVTTHYMEEAEV--LGDTICILANGKLQSIGSP 675
            ::..|||:||||..|..::..::..|.:....:|.|.:...|::  |.|.:.:|:.|:..
  Rat   237 VMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIVCTIHQPSAKLFELFDQLYVLSQGQCV----- 296

  Fly   676 LELKRKSGIGYRLKLEINDFTSREVEIMEIIHHFVPTARVLNVVNPTVYICLPYAYKNCFAQMLY 740
                      ||.|                :.:.||..|.|.:..||        |.|   ...:
  Rat   297 ----------YRGK----------------VSNLVPYLRDLGLNCPT--------YHN---PADF 324

  Fly   741 RLETESKELGIHTISMTDTSLEDVFLRCAGEQDQVDTPDGSRNDAPLLAHYKRLQDHPPHRGLFQ 805
            .:|..|.|.|.....:.....|.:   |..:..:....||..|  |.|.|....:|.....|..
  Rat   325 VMEVASGEYGDQNSRLVRAVREGM---CDSDYKRELGGDGDVN--PFLWHRPAEEDSASMEGCH- 383

  Fly   806 LWMAVFYKKWTFISNEWLYTLIMLCIPFVCVFGAILVMHAMSLVENEEALPLKL-SQMGSGVIYV 869
                      :|.::    .|...||.|...|        :|::.:.....|:: |.:|.|:
  Rat   384 ----------SFSAS----CLTQFCILFKRTF--------LSIMRDSVLTHLRITSHIGIGL--- 423

  Fly   870 HNPTGHHAHLEQQLRQQIELNGITAKTMHLRGSNDVKNESLDLQRDNLADFLEQVIGIIDMYGGG 934
                               |.|:    ::|...|:.|.                   ::...|
  Rat   424 -------------------LIGL----LYLGIGNEAKK-------------------VLSNSG-- 444

  Fly   935 RGTSDTPTIEIFYSGNRYHSSVELINLVDSAMLKLGRPESEIDTTYVPIRRFVSDISPSRLEYYA 999
                     .:|:|         ::.|:.:|::                        |:.|.:
  Rat   445 ---------FLFFS---------MLFLMFAALM------------------------PTVLTF-- 465

  Fly  1000 VIVPIGMFFFMFYFISLPFREYANGFKQL------QTMS-------------RFTYWFAHFTFDM 1045
               |:.|..|:        ||:.|.:..|      :||:             ...||......|.
  Rat   466 ---PLEMSVFL--------REHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDA 519

  Fly  1046 LILIFVCVALFSLQSLMMPS-ELYTTAELKVIVLSIFFYGCSYLPILYALGNNFKSISTISTYLL 1109
            :..: :..||.::.||:..| .|...|....:.::.|....:.:|:|...| .|.|..||.|||.
  Rat   520 VRFV-LFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSG-FFVSFDTIPTYLQ 582

  Fly  1110 LMLIVSAI 1117
            .|..:|.:
  Rat   583 WMSYISYV 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eato	NP_001036360.1	ABC2_membrane_3	<209..347	CDD:289468
		CcmA	460..767	CDD:224054	66/285 (23%)
		ABC_subfamily_A	461..679	CDD:213230	50/197 (25%)
		ABC2_membrane_3	<937..1117	CDD:289468	38/199 (19%)
		ABC_subfamily_A	1255..1479	CDD:213230
		drrA	1262..1573	CDD:130256
Abcg1	NP_445954.2	3a01204	60..666	CDD:273361	130/658 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000