DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Eato and abca4a

DIOPT Version :9

Sequence 1:	NP_001036360.1	Gene:	Eato / 34783	FlyBaseID:	FBgn0028539	Length:	1597	Species:	Drosophila melanogaster
Sequence 2:	NP_001002206.1	Gene:	abca4a / 798993	ZFINID:	ZDB-GENE-050517-3	Length:	280	Species:	Danio rerio

Alignment Length:	249	Identity:	54/249 - (21%)
Similarity:	94/249 - (37%)	Gaps:	64/249 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VFLRK-NLLYLQR------------NLLPLL--LICSG------------FAGVLTAYLH----- 43
            |:||| |.||.|.            .:||.:  ::|:.            ..|:::.|.:
Zfish    40 VWLRKANPLYRQHECHFPNKAMPSSGVLPWIQGIVCNANNPCFQHTTRGESPGLVSNYNNSILAR 104

  Fly    44 -WS-VKPVLHQINQFEAKNEMVLRELYFPGNELDYIYYSP--ISPNVEDIMDLLRVDLGIIPERL 104
             || .:.:|.:..:|.....: .:||....:.:|.:..:|  |:.....:.|:|:.|..:....|
Zfish   105 FWSDAQELLFEDTEFLQLGRL-WQELMAMSSFMDTLRTNPEAIAGRGIKVEDILKDDETLTAYLL 168

  Fly   105 R--PNNNSFEMQLEMEQQCRGSCFAI---DFHR---------------VPNRGSDRKFRYSLSSN 149
            |  |...|...|| :..|.|...||.   |.|.               .|||..    .|::.:.
Zfish   169 RDVPLTESVVQQL-INSQIRPEQFAYGVPDLHLKDIACSQTLLERFLIFPNRWG----LYAVRNA 228

  Fly   150 QMRISPRKRFVNDEEIYHQIDDDDYIRSGFLSLQHILDKQYMKYQELGKDFEVV 203
            ...::|::..:.:::.|..:|.....|  .:||...|.|..|....||.:.|.|
Zfish   229 MCVLTPQRLQIIEDKFYANLDFFKLFR--LVSLLTHLVKTIMLEMALGVEDEWV 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eato	NP_001036360.1	ABC2_membrane_3	<209..347	CDD:289468
		CcmA	460..767	CDD:224054
		ABC_subfamily_A	461..679	CDD:213230
		ABC2_membrane_3	<937..1117	CDD:289468
		ABC_subfamily_A	1255..1479	CDD:213230
		drrA	1262..1573	CDD:130256
abca4a	NP_001002206.1	rim_protein	1..>260	CDD:130324	46/227 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582256
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53524
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100045
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.750