Protein Alignment Eato and abcg2a

DIOPT Version :9

• Sequence 1: NP_001036360.1
• Gene: Eato / 34783
• FlyBaseID: FBgn0028539
• Length: 1597
• Species: Drosophila melanogaster
• Sequence 2: XP_021325521.1
• Gene: abcg2a / 735312
• ZFINID: ZDB-GENE-050517-35
• Length: 644
• Species: Danio rerio
• Alignment Length: 804
• Identity: 154/804 - (19%)
• Similarity: 284/804 - (35%)
• Gaps: 281/804 - (34%)

  Fly   467 CKKFQTSKRDTLISDNLNMTINNKEITVLLGHNGAGKTTMMNMIMGLVPKD----SGKIIVCSER 527
            ||. :::|::.||..|   .|....:..:||..|:||::.::::  ...||    ||::::....
Zfish    49 CKS-KSTKKNILIGLN---GIMKPGLNAILGATGSGKSSFLDVL--AARKDPAGLSGEVLIDGAP 107

  Fly   528 DVASYRHLIGFCPQHSVFMSYMTCHQHLEFFAQLRGACRSDARDWADEK----LKKLGLS---DK 585
            ...:::.|.|:..|..|.|..:|..::|.|.|.|| ..:|..:...|||    :::||||   |.
Zfish   108 QPPNFKCLSGYVVQDDVVMGTLTVRENLRFSAALR-LPKSIKQREKDEKVERLIQELGLSKVADS 171

  Fly   586 R--NEFGKNLSGGMKRRLSLGIAIAGNTKIVILDEPSSGLDINSRRELWDILLNLRK----EKAV 644
            |  .:..:.:|||.::|.::|:.:..:..::.||||::|||.::..   .:|:.|:|    .:.:
Zfish   172 RVGTQLIRGVSGGERKRTNIGMELIIDPPVLFLDEPTTGLDASTAN---SVLMLLKKMGNNGRTI 233

  Fly   645 LVTTHYMEEAEV-LGDTICILANGKLQSIGSPLE-LKRKSGIGYRLKLEINDFTSREVEIMEIIH 707
            :::.|....:.. |.|::.:|..|||...|...: |...|.|||..:                 .
Zfish   234 ILSIHQPRYSIYRLFDSLTLLVGGKLVYHGPAQDALSYFSQIGYTCE-----------------P 281

  Fly   708 HFVPTARVLNVVNPTVYICLPYAYKNCFAQMLYRLETESKELGIHTISMTDTSLEDVFLRCAGEQ 772
            |..|....|:|:|                       .:|..:.::.:      .|:|.     :|
Zfish   282 HNNPADFFLDVIN-----------------------GDSSAVTLNKL------YEEVV-----DQ 312

  Fly   773 DQVDTPDGSRNDAPLLAHYKRLQDHPPHRGLFQLWMAVFYKKWTFISNEWLYTLIMLCIPFVCVF 837
            ||:.:......|. |:..|:|       ..:||
Zfish   313 DQLSSSLKGIEDR-LVEEYQR-------SSIFQ-------------------------------- 337

  Fly   838 GAILVMHAMSLVENEEALPLKLSQMGSGVIYVHNPTG----------HHAH--LEQQLRQQIELN 890
                ..||            .|.::..|..|...|..          |..|  |::..|
Zfish   338 ----QTHA------------DLQRIVQGQDYSTRPKSRTITYSTSFCHQFHWVLKRTFR------ 380

  Fly   891 GITAKTMHLRGSNDVKNESLDLQRDNLADFLEQVIGIIDMYG---GGRGTSDTPTIEIFYSGNRY 952
                        |.:.|....:.:..:..||..|:|.| .:|   ...|..:......|.:.|:.
Zfish   381 ------------NLMLNPQTSVAQIGVMIFLALVVGAI-FFGVAENSSGIQNRMGALFFITTNQC 432

  Fly   953 HSSVELINLVDSAMLKLGRPESEIDTTYVPIRRFVSDISPSRLEYYAVIVPIGMFFFMFYFISLP 1017
            .|||....|                  ::..|:.                          |:
Zfish   433 FSSVSAAEL------------------FIAERKL--------------------------FV--- 450

  Fly  1018 FREYANGFKQLQTMSRFTYWFAHFTFDMLIL------IFVCVALFSLQSLMMPSELYTTAELKVI 1076
             .||.:|:.::.     .|:.:....|:|.|      ||.|||.|.: .|...:|.:......:|
Zfish   451 -HEYISGYYRVS-----VYFLSKILSDILTLRTIPAVIFSCVAYFMI-GLKPAAEAFFIFLFSII 508

  Fly  1077 VLSIFFYGCSYLPI-------LYALGNNFKSISTISTYLLLMLIVS--AIAP--------LITSS 1124
            ::|   |..:.:.:       :.|:.|.|.:||.:...:...|:|:  ::|.        .|...
Zfish   509 MVS---YTATAMTLAISADQTVVAIANIFMTISFVFMMIFSGLLVNLPSVATWLNWLKYFSIPRY 570

  Fly  1125 NAAAMKLHETKIAFLCFLPDFNLNHQFRIIN--ENFITRRHPALIKGLISQDTFFAYAT------ 1181
            ..:|::::|....|.|    .|.|:...:.:  |.|:             |:....|:.
Zfish   571 GLSALQINEFTGLFFC----DNRNNSGSVCSSGEEFL-------------QEQGIDYSAWGLWQN 618

  Fly  1182 --AVGVMVMAFFTIVLEHKYLRRR 1203
              |:|:|...|..|.    ||:.|
Zfish   619 HLALGIMTFIFLCIA----YLKLR 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eato	NP_001036360.1	ABC2_membrane_3	<209..347	CDD:289468
		CcmA	460..767	CDD:224054	73/318 (23%)
		ABC_subfamily_A	461..679	CDD:213230	60/230 (26%)
		ABC2_membrane_3	<937..1117	CDD:289468	33/194 (17%)
		ABC_subfamily_A	1255..1479	CDD:213230
		drrA	1262..1573	CDD:130256
abcg2a	XP_021325521.1	PRK10535	43..638	CDD:333000	153/802 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000