Protein Alignment Eato and CG43672

DIOPT Version :9

• Sequence 1: NP_001036360.1
• Gene: Eato / 34783
• FlyBaseID: FBgn0028539
• Length: 1597
• Species: Drosophila melanogaster
• Sequence 2: NP_788912.3
• Gene: CG43672 / 318910
• FlyBaseID: FBgn0263747
• Length: 1690
• Species: Drosophila melanogaster
• Alignment Length: 1613
• Identity: 328/1613 - (20%)
• Similarity: 611/1613 - (37%)
• Gaps: 314/1613 - (19%)

  Fly   158 RFVNDEEIYHQIDDD---DYIRSGFLSLQHILDKQYM-----KYQELGKDFEVVVSSMPNMEVIS 214
            |.|.:|:   :.|:|   ||:..||:.||:.:..|::     |.::|.|......:..||: ::|
  Fly   197 RDVAEED---EFDEDGYTDYMGEGFVPLQYHISMQFLRATASKVEKLPKVVMRRFNENPNV-LLS 257

  Fly   215 MDSHRLTYFGTLCSILFNVVLLSSFVVPFVEEKQNGLKEFLNLVTPMS-------FLNGLTFFLI 272
            ...........|...:|.|.:|::.:   |||::.|.:..|.::...:       |.|..|.|||
  Fly   258 EGIGTSVVLLILLGFMFPVTILTTLI---VEERELGQRYMLKILNASATLQMAAWFFNVFTHFLI 319

  Fly   273 RFVCYTLLMIFVLVVAYLYKALGSI--CFAYVAVLFLL-YILSTMSYAYLISICFHSVFYAKIGG 334
                 |.|:|.:|:......|..::  |...:.:.||: |..|..|...|::...      :...
  Fly   320 -----TSLLITILLKIEWNGATAAVNKCPWPILLCFLISYGCSVTSLIILMTSAM------RRSR 373

  Fly   335 LAMLIIPYAFSFVRSWATSLAFVCFSTNTFL-EGLDIFQTFS-----NKRKNR------------ 381
            :||::.|..      |.. ||....|....| :|.|:|..|:     |...:|
  Fly   374 VAMVMAPII------WIL-LALPLLSKKELLSDGPDVFYGFATVLLCNVSFSRGLSKIFYIEDYT 431

  Fly   382 ---EFGAVDVFRVIKSNSSTMFSVYVVLVFQSFLYAMLYNYLGCVFPGPGGLKRPMFFFLD---- 439
               ..|....:||.||:    |.::|.:|. .::..:....|..:|      :...:|:|.
  Fly   432 LGVTIGKYMFYRVSKSD----FGIFVPIVC-FYVQTIFCTLLAMIF------ENNAYFWLAIRVK 485

  Fly   440 --PKTY---------MKRQRNEYTTTPRGTHAIIITELCKKFQTSKRDTLISDNLNMTINNKEIT 493
              .|.|         :|||..|.:.:.....|:|  |....:|.....|.:..::.:.:...|:.
  Fly   486 NLLKKYHATRSAVGRLKRQIPEVSFSKTSAEALI--EFRGVWQKYSNSTYVVQDITLNVYAGEVV 548

  Fly   494 VLLGHNGAGKTTMMNMIMGLVPKDSGKIIVCSERDVASYRHLIGFCPQHSVFMSYMTCH------ 552
            .|||||.:||:|::.|:.|......|:|.:.....|...:..:   ...|:.|||.|..
  Fly   549 ALLGHNASGKSTIIKMLYGRTRPKLGEIYLSGFNIVTQRKEAL---KNSSISMSYKTLFTELVVL 610

  Fly   553 QHLEFFAQLRGACRSDARDWADEKLKKLGLSDKRNEFGKNLSGGMKRRLSLGIAIAGNTKIVILD 617
            .||.|.::|||..:::|:..|...|:.|.|.|.......:|:.|.:|.|....|.||..:|||||
  Fly   611 DHLVFLSRLRGLSKTEAKLEAKALLRYLKLEDWEKTLVNDLTIGQRRVLQFLCAFAGGNQIVILD 675

  Fly   618 EPSSGLDINSRRELWDILLNLRKEKAVLVTTHYMEEAEVLGDTICILANGKLQSIGSPLELKRKS 682
            :|..|:|.......:.::|:.:|.:::..|::..:.|..:.|.|.:|:.||||:.|:..:|.|..
  Fly   676 KPFDGIDEQRTSLFYSLILDQKKNRSIFFTSNNQKVASGIADRIFVLSKGKLQAFGTVKKLCRML 740

  Fly   683 GIGYRLKLEINDFTSREVEIMEIIHHFVPTARVLNVVNPTVYICLPYAYKNCFAQMLYRLETESK 747
            ...|||.:..|:..|.: ::...:..|:|...:.:::.......:.:.|......::..|.....
  Fly   741 NESYRLIIFGNEKCSFK-DVYAFMATFIPEIEMDSILADCASFLVKHKYHTELINLIENLARLKN 804

  Fly   748 ELGIHTISMTDTSLEDVFLRCAGEQDQVDTPDGSRNDAPLLAHYKR-------------LQDHPP 799
            :|.:::..:.:.|::|: |.....:|:.....|......|||..::             |::
  Fly   805 DLNVYSFEIHECSIDDI-LASLYTRDKSTLEFGQPGLQTLLASRQQSAKRRFIIPTMYLLEE--- 865

  Fly   800 HRGLFQLWMAVFYKKWTFISNEWLYTLIMLCIPFVCVFGAILVMHAMSLVENEEALPLKLSQMGS 864
               |.||.:|        .:..|...::.|.:|.:.|...:.:.:..........:...:|..|.
  Fly   866 ---LRQLLIA--------DTRNWFLPILKLTLPSLVVVWTLSMPYFWHNCRQPGHITFPMSDHGD 919

  Fly   865 GVIYVHNPTGHHAHLEQQLRQQIELN---GITA--KTMHLRG---SNDVKNESLDLQRDNLADFL 921
            |:|.:...|     |:.:|....|:.   |:|.  ||:.:..   :.:.||..|     :.||.:
  Fly   920 GIILMQKDT-----LDSELLVASEMYAKVGVTEVDKTVDITTFIYNYEYKNSLL-----SDADIM 974

  Fly   922 EQVIGIIDMYGGGRGTSDTPTIEIFYSGNRYH----SSVELINLVDSAMLKLGRPESEIDTTYVP 982
            |.||            .....||:.::....|    |..:.:|.:..|.:. |....:::...:|
  Fly   975 EAVI------------FSNVQIEVLFNTKWPHTAPDSLAQALNSLAVAFID-GDAGIKVELEVLP 1026

  Fly   983 IRRFVSDISPSRLEYYAVIVPIGMFFFMFYFISLPFREYA-------NGFKQLQTMSRFTYWFAH 1040
            .....:......::.|.:|....:.|...:..|:|.....       |..:.:..|.......|.
  Fly  1027 FSTIHTLQLHLNIDGYDLIFASCLSFCFCFIWSIPLLHMTLSRDGRYNYVELIAGMPTIVLIVAF 1091

  Fly  1041 FTFDMLILIFVCVALFSLQ--------SLMMPS--ELYTTAELKVIVLSIF-------FYGCSYL 1088
            ..:::|:   |.:|||.:.        .|:|.|  .:|:...:.:|...:|       ....|.:
  Fly  1092 LIYELLV---VLLALFPINIAVIFFHWDLLMDSNIHIYSVYVMFIIAACVFSLNILITIMPISDM 1153

  Fly  1089 PILYALGNNFKSISTISTYLLLMLIVSAIAPLITSSNAAAMKLHETKIAFLCFLPDFNLNHQF-- 1151
            |.:|     .|.:...|..:|:.:.|..:.| .|:.|.|...|       |.|.|.:.|.|..
  Fly  1154 PFVY-----LKVLLAYSLGILVYIAVKELRP-FTNPNTAHFLL-------LDFHPFYALLHNLMR 1205

  Fly  1152 -------------RIINENFITRRHPALIKGLISQDT--FF-------AYATAVGVMVMAFFTIV 1194
                         |.|.|..:.......|......|.  |:       .|...|.|.:..|  |.
  Fly  1206 IASISEKIWLCSDRQIYETSVYADQCNTIPNCCDDDAQEFYHLRYLCCVYLLLVVVWISIF--IF 1268

  Fly  1195 LEHKYLRRRIHDGIWEWAFQRKKYNSTGTLPSTPISEIDDC-AREEKRVTDLIKDPLNDHSLIVH 1258
            |:...::||.....:.|............|.....||:::. ..|:.||:.|.::.:...:|.|.
  Fly  1269 LKSHMVKRRPRQPKYFWDSDPDSKYDQNILHIMEPSELENTWIHEKSRVSTLERNHIESKALHVE 1333

  Fly  1259 NLRKRYGDKLAVDGVSFAAAQGECFGLLGVNGAGKTSTFQ-MIAANLPLDGGTIRIKGADIREHE 1322
            :|...:|.|.|:..:.|...:.:...:.|.||.||:...: ::....|..|..|..|....:..:
  Fly  1334 HLSVFFGLKAAIKHIDFMVNRYQVMSVFGANGTGKSVLLKTILGIYTPSSGRIISSKTVPFKSKD 1398

  Fly  1323 LKYREYFGYCPQYDALNKFMTAEQCLYYMALLRGLSRR------RTDGPASCKEHVKYWLEKMHL 1381
            |......||..|.....:.||..:.  :..:||  .||      |.:....||....|
  Fly  1399 LDSCHMVGYSAQEFQTMQLMTILET--WDLILR--IRRSKQISFRAEATKLCKIFGLY------- 1452

  Fly  1382 TKYQKVQVRHYSGGTKRKLLAAMAMIGAPALVLLDEPTTGVDPISRRFLWQCIKDFQGKDRTVVL 1446
             ||:...:...|.|..::|...:|::....|:|||:|.|.:|.:|:|.:...|.|.:.:..:::.
  Fly  1453 -KYRFNSLSICSQGVLKRLSLGIALMSDAELILLDDPFTHLDIVSQRSMLHIIHDLRRRGHSIIY 1516

  Fly  1447 TSHSMDECEELCN-----RLAIMAHGKFKCLNNICALKR---LSGFTIKLKM------------K 1491
            |      |.:...     |:|.:::.....:.....:::   .|.:.::.::            .
  Fly  1517 T------CSDTAYSTPALRMATLSYPGIAVIGEREEMQQNYYSSYYMVETRIHLAELGSPIDFDS 1575

  Fly  1492 ADTETEMNVSTITGTLKSEFPGLELRESHAGTLTYFVSTQE------------------------ 1532
            ..||.:.:.:..||||        ||..|......|..:.:
  Fly  1576 QSTEAKEDRAGTTGTL--------LRHKHQEFSAAFTDSADRWKYLKLCGVIENVFPHAIIKNVS 1632

  Fly  1533 --SVVLWSSVFKIAEEYLGDRLSALVAD---YSVNECTLEDIFLKFEREAKSQ 1580
              .|..|.|........:.|.|.....|   :||::.::..:||...|:..::
  Fly  1633 FPRVCFWLSSHMYPMSRIVDTLHRNKQDFYSFSVSQPSVNSVFLSIHRQKSNK 1685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eato	NP_001036360.1	ABC2_membrane_3	<209..347	CDD:289468	32/147 (22%)
		CcmA	460..767	CDD:224054	77/312 (25%)
		ABC_subfamily_A	461..679	CDD:213230	62/223 (28%)
		ABC2_membrane_3	<937..1117	CDD:289468	34/207 (16%)
		ABC_subfamily_A	1255..1479	CDD:213230	51/235 (22%)
		drrA	1262..1573	CDD:130256	69/366 (19%)
CG43672	NP_788912.3	rim_protein	<266..>732	CDD:130324	121/502 (24%)
		ABC_subfamily_A	519..737	CDD:213230	62/222 (28%)
		P-loop_NTPase	1330..1517	CDD:422963	47/198 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451212
Domainoid	1	1.000	42	1.000	Domainoid score	I3675
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X215
	7	6.950