Protein Alignment Eato and Abcg1

DIOPT Version :9

• Sequence 1: NP_001036360.1
• Gene: Eato / 34783
• FlyBaseID: FBgn0028539
• Length: 1597
• Species: Drosophila melanogaster
• Sequence 2: NP_033723.1
• Gene: Abcg1 / 11307
• MGIID: 107704
• Length: 666
• Species: Mus musculus
• Alignment Length: 685
• Identity: 134/685 - (19%)
• Similarity: 236/685 - (34%)
• Gaps: 209/685 - (30%)

  Fly   488 NNKEITVLLGHNGAGKTTMMNMIMGLVPKDSGK----IIVCSERDVASYRHLIGFCPQHSVFMSY 548
            |:.|:..::|.:||||:|:||::.|.  :::|.    :|....||:..:|.:..:..|..:.:.:
Mouse   109 NSGELVAIMGPSGAGKSTLMNILAGY--RETGMKGAVLINGMPRDLRCFRKVSCYIMQDDMLLPH 171

  Fly   549 MTCHQHLEFFAQLRGACRSDA-RDWADEKLKKLGLSDKRNEFGKNLSGGMKRRLSLGIAIAGNTK 612
            :|..:.:...|.|:...:.:. |:...|.|..|||....|....:||||.::||::.:.:..|..
Mouse   172 LTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLPCANTRTGSLSGGQRKRLAIALELVNNPP 236

  Fly   613 IVILDEPSSGLDINSRRELWDILLNLRKEKAVLVTTHYMEEAEV--LGDTICILANGKLQSIGSP 675
            ::..|||:||||..|..::..::..|.:....:|.|.:...|::  |.|.:.:|:.|:..
Mouse   237 VMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIVCTIHQPSAKLFELFDQLYVLSQGQCV----- 296

  Fly   676 LELKRKSGIGYRLKLEINDFTSREVEIMEIIHHFVPTARVLNVVNPTVYICLPYAYKNCFAQMLY 740
                      ||.|                :.:.||..|.|.:..||        |.|   ...:
Mouse   297 ----------YRGK----------------VSNLVPYLRDLGLNCPT--------YHN---PADF 324

  Fly   741 RLETESKELGIHTISMTDTSLEDVFLRCAGEQDQVDTPDGSRNDAPLLAHYKRLQDHPPHRG--- 802
            .:|..|.|.|.....:.....|.:   |  :.|......|..:..|.|.|....:|.....|
Mouse   325 VMEVASGEYGDQNSRLVRAVREGM---C--DADYKRDLGGDTDVNPFLWHRPAEEDSASMEGCHS 384

  Fly   803 -----------LFQ-----------------------------LWMAVFYKKWTFISNEWLYTLI 827
                       ||:                             |::.:..:....:||.......
Mouse   385 FSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFS 449

  Fly   828 MLCIPFVCVFGAILVMHAMSLVENEEALPLKLSQMGSGVIYVHNPTGHHAHLEQQLRQQIELNG- 891
            ||.:.|..:...:|            ..||::|                ..|.:.|.....|..
Mouse   450 MLFLMFAALMPTVL------------TFPLEMS----------------VFLREHLNYWYSLKAY 486

  Fly   892 ITAKTMHLRGSNDVKNESLDLQRDNLADFLEQVIGIID----MYGGGRGTSDTPTIEIFYSGNRY 952
            ..||||                    ||...|::..:.    :|......||.....:|.:....
Mouse   487 YLAKTM--------------------ADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTM 531

  Fly   953 HSSVELINLVDSAMLKLGRPESEIDTTYVPIRRFVSDISPSRLEYYAVIVPIGMFF-FMFYFISL 1016
            .|.|     ..|..|.:|..     :|.:.:..||..::         .:|:.:|. |...|.::
Mouse   532 TSLV-----AQSLGLLIGAA-----STSLQVATFVGPVT---------AIPVLLFSGFFVSFDTI 577

  Fly  1017 PFREYANGFKQLQTMSRFTYWFAHFTFDMLILIFVCVALFSLQSLMMPSELYTTA---------- 1071
            |        ..||.||..:|  ..:.|:.:||     :::.|....:..::..|.
Mouse   578 P--------AYLQWMSYISY--VRYGFEGVIL-----SIYGLDREDLHCDIAETCHFQKSEAILR 627

  Fly  1072 ELKV---------IVLSIFFYG---CSYLPILYAL 1094
            ||.|         |||.|||..   .:|..:.|.:
Mouse   628 ELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKI 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eato	NP_001036360.1	ABC2_membrane_3	<209..347	CDD:289468
		CcmA	460..767	CDD:224054	66/285 (23%)
		ABC_subfamily_A	461..679	CDD:213230	50/197 (25%)
		ABC2_membrane_3	<937..1117	CDD:289468	37/181 (20%)
		ABC_subfamily_A	1255..1479	CDD:213230
		drrA	1262..1573	CDD:130256
Abcg1	NP_033723.1	3a01204	60..666	CDD:273361	134/685 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000