Protein Alignment Eato and abca9

DIOPT Version :9

• Sequence 1: NP_001036360.1
• Gene: Eato / 34783
• FlyBaseID: FBgn0028539
• Length: 1597
• Species: Drosophila melanogaster
• Sequence 2: XP_031750505.1
• Gene: abca9 / 100496782
• XenbaseID: XB-GENE-6464273
• Length: 1608
• Species: Xenopus tropicalis
• Alignment Length: 1576
• Identity: 399/1576 - (25%)
• Similarity: 692/1576 - (43%)
• Gaps: 303/1576 - (19%)

  Fly   174 YIRSGFLSLQHILDKQYMKYQELGKDFEV-----VVSSMPNMEVISMDSHRLTYFGTLCSILFNV 233
            |...||||||..:|...:         ||     |.::|.::..|.|.|.:|||        ..:
 Frog   171 YWSEGFLSLQASIDSAII---------EVTSNHSVWNNMASIVAIKMKSAQLTY--------RRL 218

  Fly   234 VLLSS--FVVP------------FVEEKQNGLKEFLNLVTPMSFLNGLTFFLIRFVCYTLLMIFV 284
            |.::|  ||:|            :|..::..:||.|.|:.    |..|.|:|...:.|.   .::
 Frog   219 VHVASFVFVMPMCYVSLIYLLSLYVTRERYEMKETLRLMQ----LKDLAFWLSWGLLYA---GYI 276

  Fly   285 LVVA-----------YLYKALGSICFAYVAVLFLLYILSTMSYAYLISICFHSVFYAKIGGLAML 338
            |:||           ::..:.|.|.|     ||.||.::.||:.:::|..|.|.....:.|..:.
 Frog   277 LIVANLMTLITKPFIFMTSSYGVIMF-----LFFLYGVALMSFTFMLSALFRSPRATAVAGFFIT 336

  Fly   339 IIPYAFSFV---RSWATSLAFVCFSTNTFLEGLDIFQTFS-------NKRKNREFGAVDVFRVIK 393
            :...|...|   :.:..:||.:          |.||..|:       :...:.:...| .|..:.
 Frog   337 LFLSAVGLVLLRKDFPQALAVL----------LSIFPQFAFAVGLLQSVHMDSDLEGV-YFSDLM 390

  Fly   394 SNSSTMFSVYVVLVFQSFLYAMLYNYLGCVFPGPGGLKRPMFFFLDPKTYMKRQ------RNEYT 452
            .:||.|.|.::.||..|..|.:|..|...|.....|:|....|||....:.|.:      :.:|:
 Frog   391 GDSSHMLSCFISLVLDSVFYMILTLYFEKVLADKHGVKHEPLFFLKASYWSKEKPSPLMGQTDYS 455

  Fly   453 ----------TTP---RGTHAIIITELCKKFQTSKRDTLISDNLNMTINNKEITVLLGHNGAGKT 504
                      ..|   .|..||.|..:.|.|....:.|.....|::.|...:||.||||:|||||
 Frog   456 GESSLGDFVEKVPDDLHGKEAIRIHGVKKTFSDKDKSTEALRGLDLNIYEGQITALLGHSGAGKT 520

  Fly   505 TMMNMIMGLVPKDSGKIIVCSERDVASYRHL------IGFCPQHSVFMSYMTCHQHLEFFAQLRG 563
            |::|::.|:.|...|...:|:.: :::.|||      :|||||..:....:|..::|..||.::|
 Frog   521 TLLNILSGMYPASGGSATICNYK-LSNMRHLEEIKKRVGFCPQGDIKFDPLTVKENLMVFAMIKG 584

  Fly   564 ACRSDARDWADEKLKKLGLSDKRNEFGKNLSGGMKRRLSLGIAIAGNTKIVILDEPSSGLDINSR 628
            ...........:.|..|.::|..|.....||||.:|:|:.||||.|:.::::||||::|||..||
 Frog   585 IPTKQVAHKVQKVLSDLQMNDIENTEAITLSGGQRRKLTFGIAILGDPQVLLLDEPTAGLDPCSR 649

  Fly   629 RELWDILLNLRKEKAVLVTTHYMEEAEVLGDTICILANGKLQSIGSPLELKRKSGIGYRLKLEIN 693
            ..:|.||...:.::..|.:|.:|:||::|.|...:::.|:|:.:||.|.||||.||||.|:::::
 Frog   650 HHVWTILKENKADRVTLFSTQFMDEADILADRKAVISKGRLKCVGSSLFLKRKWGIGYHLRMQVS 714

  Fly   694 DFTSREVEIM-EIIHHFVPTARVLNVVNPTVYICLPYAYKNCFAQMLYRLETE-SKELGIHTISM 756
              .|.:||:| .||...:|:|::.......:...||:...:.|..:...|:.: ...:..:.:||
 Frog   715 --PSCDVELMTSIIKQRIPSAKLTAQNEEELTYALPFENMDVFPDLFSHLDGQVGNSIVSYGVSM 777

  Fly   757 TDTSLEDVFLRCAGE------------------QDQVDTPDGSRNDAPLLAHYKRLQDHPPHRGL 803
              |:|:||||:..||                  :|:.|..........|::....:.     ...
 Frog   778 --TTLDDVFLKLEGEGEIESGDYDVFNPESRTAEDRYDISAEMEESLLLMSDSGNVT-----LSG 835

  Fly   804 FQLW----MAVFYKKWTFISNEW--LYTLIMLCIPFVCV-FGAILVMHAMSLVENEEALP-LKLS 860
            ::||    :||...::..:.::.  |.::::|.:.|:.. ..:|::.|..:...:.|..| |...
 Frog   836 WELWRQQVLAVARIRFLKLRHDTKSLRSILLLLVLFILASILSIIMAHISNKFISWELTPSLYFQ 900

  Fly   861 QMGSGV------IYVHNPTGHH------AHLEQQLRQQIELNGITAKTMHLRGSNDVKNESLDLQ 913
            ..||.:      :.:||.||..      |..||.:..|:........|:..||:.:|....
 Frog   901 SPGSRLNKYYTDLLIHNNTGSSIDDFIGAVKEQNIAVQVANGKYDMDTIKYRGAIEVSQAE---- 961

  Fly   914 RDNLADFLEQVIGIIDMYGGGRGTSDTPTIEIFYSGNRYHSSVE-LINLVDSAMLKLGRPESEID 977
                                 :|.:.|     ..:..:.|:::. |:|::.:|:||:.:....:.
 Frog   962 ---------------------KGYNFT-----IVANPKAHNALPVLLNIISNALLKVFKVSEHVR 1000

  Fly   978 TTYVPIRRFVSDISPSRLEYYAVIVPIGMFFFMFY-----FISLPFRE--YANGFKQLQTMSRF- 1034
            ....||.....||      ::...:.| |||.:|.     .|::...|  ..|...||:....|
 Frog  1001 VWNHPITMDEMDI------HHKTYISI-MFFMIFASGLSPHIAMSSTEDNRINARTQLRLAGLFP 1058

  Fly  1035 -TYWFAHFTFDMLI---LIFVCVA-LFSLQSLMMPSELYTTAELKVIVLSIFFYGCSYLPILYAL 1094
             .|||.....|:::   |:|:..| ||:..:.......:.||  .|::..:|.||.:.:..:|.:
 Frog  1059 SAYWFGQALVDVILYWSLLFLMTAILFAFNNYSYFLLNFITA--MVMIAGMFGYGMAVILYVYVI 1121

  Fly  1095 GNNF-KSISTISTYLLLMLIVSAIAPLITSSNAAA------MKLHETKIAFLCFLPDFNLNHQFR 1152
            ...| |......::.|..:|::    ...:||..:      :.|....:..|..:.|:..:.||.
 Frog  1122 SFIFGKGKIHRDSWSLFFVIIT----FFPASNEISIFPWFYIYLFIFPVTTLYGIMDYTEDLQFL 1182

  Fly  1153 IINENFITRRHPALIKGLISQDTFFAYATAVGVMVMAFFTIV--LEHKY-LRRRIHDGIWEWAFQ 1214
            ...:|||....|.|                   .::.||.::  ||.|: ||....|.:    |:
 Frog  1183 QEADNFILPCTPYL-------------------HIIIFFGLLWFLEWKFGLRSLTTDPL----FR 1224

  Fly  1215 RKKYNST-GTLPSTPISEIDDCAREEKR-------VTDLIKDPLNDHSLIVHNLRKRY------- 1264
            ..:.|.| ...|....:::|:....||.       |.::.:.|:    :||.:|||.|
 Frog  1225 ISRRNMTVKKNPEELGNDVDEDVLAEKERVKNAATVANVEEKPV----IIVDSLRKEYKVKKRGS 1285

  Fly  1265 ----GDKLAVDGVSFAAAQGECFGLLGVNGAGKTSTFQMIAANLPLDGGTIRIKGADIREHELKY 1325
                ..|.|...:||...:||..||||.||||||::..|:|..:....|.:.:.|.|..|.
 Frog  1286 FFKKNRKAATKNISFCVRKGEVLGLLGPNGAGKTTSMYMLAGEVKPTAGEVVLCGNDPAES---- 1346

  Fly  1326 REYFGYCPQYDALNKFMTAEQCLYYMALLRGLSR-------RRTDGPASCKEHVKYWLEKMHLTK 1383
            ..:.|||||.:.|...:|.::.|...|.::|:.:       .|.......|||:.....|:.|
 Frog  1347 TGFLGYCPQDNPLWPNLTVKEHLEIYAAVKGMKKEDAYIAINRVAAALELKEHMGKESRKLSL-- 1409

  Fly  1384 YQKVQVRHYSGGTKRKLLAAMAMIGAPALVLLDEPTTGVDPISRRFLWQCIK-DFQGKDRTVVLT 1447
                       |..||:..|::|||.|.:||||||:||:||.:::.||:.|: .|:.|||..:||
 Frog  1410 -----------GESRKVCFAISMIGNPNIVLLDEPSTGLDPKAQQRLWRAIRAAFKNKDRGAILT 1463

  Fly  1448 SHSMDECEELCNRLAIMAHGKFKCLNNICALKRL--SGFTIKLKMKADTETEMNVSTITGTLKSE 1510
            :|.|:|.|.:|:|:|||..||.:|:.:|..||..  .|:.:::|:|   ||. .|..|...:...
 Frog  1464 THYMEEAEAVCDRVAIMVSGKLRCIGSIQQLKSKFGKGYLLEIKVK---ETH-QVDQIHNEIIRI 1524

  Fly  1511 FPGLELRESHAGTLTYFVSTQESVVLWSSVFKIAEEYLGDRLSALVADYSVNECTLEDIFLKFER 1575
            ||....::..:..|.|.: ..::|...|..|.:.||   .:.:..:.:||.::.|||.:|::..:
 Frog  1525 FPHAARQDRFSSLLVYKI-PMDNVQSLSQAFLLLEE---AKRAYNIEEYSFSQSTLEQVFIELAK 1585

  Fly  1576 EAKSQSTSRQTSVQRR 1591
            |.:.:......:.|.|
 Frog  1586 EQEKEDFELNNTFQWR 1601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eato	NP_001036360.1	ABC2_membrane_3	<209..347	CDD:289468	38/162 (23%)
		CcmA	460..767	CDD:224054	105/314 (33%)
		ABC_subfamily_A	461..679	CDD:213230	76/223 (34%)
		ABC2_membrane_3	<937..1117	CDD:289468	42/194 (22%)
		ABC_subfamily_A	1255..1479	CDD:213230	84/242 (35%)
		drrA	1262..1573	CDD:130256	104/331 (31%)
abca9	XP_031750505.1	rim_protein	<170..1595	CDD:130324	397/1568 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010