DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16890 and FRA10AC1

DIOPT Version :9

Sequence 1:	NP_609671.1	Gene:	CG16890 / 34781	FlyBaseID:	FBgn0028932	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	NP_001334641.1	Gene:	FRA10AC1 / 118924	HGNCID:	1162	Length:	315	Species:	Homo sapiens

Alignment Length:	260	Identity:	106/260 - (40%)
Similarity:	164/260 - (63%)	Gaps:	34/260 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LSAKERHNYILSNYVLNLPNETE-----SRRHKRDIDVIRENHRFLW-EDDELDSDTLSWEQRLA 72
            :.|.:||...:::|:|....:.|     ....|.|:||||||||||| |:||:|   ::||:|||
Human    71 MDAYQRHTKFVNDYILYYGGKKEDFKRLGENDKTDLDVIRENHRFLWNEEDEMD---MTWEKRLA 132

  Fly    73 LRYYRKLFKEYCIADLSRYKENKIALRWRTEQEVVTGTGQFQCGSRHCGERDNLRSWEVNFRYIE 137
            .:||.||||||||||||:|||||...|||.|:||::|.|||.||:::|.:::.|:||||||.|||
Human   133 KKYYDKLFKEYCIADLSKYKENKFGFRWRVEKEVISGKGQFFCGNKYCDKKEGLKSWEVNFGYIE 197

  Fly   138 KGEPLNALVKVRLCPTHTDQLNYRTKKRECKKRRRREKEERRAEK---KRKR--------RKLDV 191
            .||..|||||:|||...:.:||:..:::|.|.::|::|.::..|:   |:.|        :|.|.
Human   198 HGEKRNALVKLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDK 262

  Fly   192 GHESSGEEEEEPVEPASESHPEASKEPTDSKDATTADEQIWQQQPDISREQASREQEFERYLEDL 256
            ||.||.:.|:..:..:.|             :.:.::.::| :.|....::.|:|:||:.|.:||
Human   263 GHSSSKKSEDSLLRNSDE-------------EESASESELW-KGPLPETDEKSQEEEFDEYFQDL 313

Fly 257 256
Human 314 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16890	NP_609671.1	Fra10Ac1	42..156	CDD:286768	73/114 (64%)
FRA10AC1	NP_001334641.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28
FRA10AC1	NP_001334641.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	226..315		24/102 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146899
Domainoid	1	1.000	164	1.000	Domainoid score	I3949
eggNOG	1	0.900	-	-		E1_KOG1297
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13852
Inparanoid	1	1.050	206	1.000	Inparanoid score	I3716
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49260
OrthoDB	1	1.010	-	-		D1444601at2759
OrthoFinder	1	1.000	-	-		FOG0006262
OrthoInspector	1	1.000	-	-		oto89839
orthoMCL	1	0.900	-	-		OOG6_104275
Panther	1	1.100	-	-	LDO	PTHR11567
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4544
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.770