Protein Alignment p38b and MAPK7

DIOPT Version :9

• Sequence 1: NP_477361.1
• Gene: p38b / 34780
• FlyBaseID: FBgn0024846
• Length: 365
• Species: Drosophila melanogaster
• Sequence 2: XP_006721620.1
• Gene: MAPK7 / 5598
• HGNCID: 6880
• Length: 822
• Species: Homo sapiens
• Alignment Length: 351
• Identity: 162/351 - (46%)
• Similarity: 229/351 - (65%)
• Gaps: 22/351 - (6%)

  Fly    18 WEIPETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYRELRLLKHMDHEN 82
            :::.:.|:.::.:|.||||.|..|..|.|..:|||||:...|....:||||.|||::|||..|:|
Human    49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDN 113

  Fly    83 VIGLLDVFHPGQPADSLDQFQQV------YMVTHLMDADLNNIIR-TQKLSDDHVQFLVYQILRG 140
            :|.:.|:..|..|   ..:|:.|      |:|..||::||:.||. :|.|:.:||::.:||:|||
Human   114 IIAIKDILRPTVP---YGEFKSVPYGVPGYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRG 175

  Fly   141 LKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLAR-----PAESE--MTGYVATRWYRAPEIML 198
            |||:|||.||||||||||:.|||:|||:|.|||:||     |||.:  ||.|||||||||||:||
Human   176 LKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELML 240

  Fly   199 NWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRISSESARNYIR 263
            :...|.|..|:||||||..|:|..|.||||.:::|||.|||.|||||:...:..:.:|..|.||:
Human   241 SLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQ 305

  Fly   264 SLPVMPRR--NFRDIFRGANPLAIDLLEKMLELDADKRITAEQALAHPYMEKYHDPTDE-QTAAL 325
            |||  ||:  .:..::.||:..|:.||.:||..:...||:|..||.||::.|||||.|| ..|..
Human   306 SLP--PRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP 368

  Fly   326 YDQSFEENELPVEKWREMVFSEVTAF 351
            :|.:|:...|..|:.:|.:.:|:..|
Human   369 FDFAFDREALTRERIKEAIVAEIEDF 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p38b	NP_477361.1	STKc_p38	8..353	CDD:143356	162/351 (46%)
		S_TKc	24..311	CDD:214567	147/302 (49%)
MAPK7	XP_006721620.1	STKc_ERK5	49..390	CDD:270842	160/345 (46%)
		S_TKc	55..353	CDD:214567	147/302 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810