DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment p38b and SRPK

DIOPT Version :9

Sequence 1:	NP_477361.1	Gene:	p38b / 34780	FlyBaseID:	FBgn0024846	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_001369087.1	Gene:	SRPK / 36706	FlyBaseID:	FBgn0286813	Length:	1009	Species:	Drosophila melanogaster

Alignment Length:	179	Identity:	55/179 - (30%)
Similarity:	82/179 - (45%)	Gaps:	42/179 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   163 EDC--ELRILDFGLARPAESEMTGYVATRWYRAPEIMLNWMHYNQTADIWSVGCIMAELLTGRTL 225
            ::|  .::|.|.|.|...:...|..:.||.||:.|:::. ..||.:|||||..|::.||.||..|
  Fly   597 DECNVHVKIADLGNACWVDRHFTEDIQTRQYRSLEVIIG-AGYNTSADIWSTACMVFELATGDYL 660

  Fly   226 FP---------GTDHIHQLNLIMEVLGTPADEFMSRISSESARNYIRSLPVMPRRNFRDIFRGAN 281
            |.         ..||:..   |:|:||....|.:.. .:.:|:::.||..:   ||    ..|..
  Fly   661 FEPHSGESYTRDEDHLAH---IIELLGPIPREILLN-GTYAAKSFTRSCEL---RN----ISGLK 714

  Fly   282 P--LAIDLLEK-----------------MLELDADKRITAEQALAHPYM 311
            |  |...||||                 |||.|.:||.||.:.|.||::
  Fly   715 PWGLMDVLLEKYEWSQKDAASFASFLTPMLEFDPNKRATAAECLQHPWL 763

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p38b	NP_477361.1	STKc_p38	8..353	CDD:143356	55/179 (31%)
p38b	NP_477361.1	S_TKc	24..311	CDD:214567	55/177 (31%)
SRPK	NP_001369087.1	PKc_like	159..>318	CDD:419665
SRPK	NP_001369087.1	PKc_like	<600..763	CDD:419665	54/174 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24055
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100