Protein Alignment p38b and MAPK15

DIOPT Version :9

• Sequence 1: NP_477361.1
• Gene: p38b / 34780
• FlyBaseID: FBgn0024846
• Length: 365
• Species: Drosophila melanogaster
• Sequence 2: XP_011515227.1
• Gene: MAPK15 / 225689
• HGNCID: 24667
• Length: 565
• Species: Homo sapiens
• Alignment Length: 357
• Identity: 135/357 - (37%)
• Similarity: 202/357 - (56%)
• Gaps: 44/357 - (12%)

  Fly    24 YQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHA-------------------KRTY 69
            ::||:     |||.|.|||.|.|...|||||:...|:....|                   :||:
Human    20 WRNLK-----AYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQDMGFLLAPPTHTPVFLSLQRTF 79

  Fly    70 RELRLLKHM-DHENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKLSDD-HVQF 132
            ||:.||:.. ||.|:|.||||.......|       :|:|...||.|||.:||...|..| ||:.
Human    80 REITLLQEFGDHPNIISLLDVIRAENDRD-------IYLVFEFMDTDLNAVIRKGGLLQDVHVRS 137

  Fly   133 LVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLAR--------PAESEMTGYVATR 189
            :.||:||..:::||..|:|||.||||:.::.:|.:::.||||||        |.:..:|.|||||
Human   138 IFYQLLRATRFLHSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATR 202

  Fly   190 WYRAPEIMLNWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRIS 254
            ||||||::|:...|....|:||:|||:.|:|.||.|||||..:|||.||:|.:..|::|.:..:.
Human   203 WYRAPEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEEDLLALG 267

  Fly   255 SESARNYIRSLPVMPRRNFRDIF-RGANPLAIDLLEKMLELDADKRITAEQALAHPYMEKYHDPT 318
            |....:.:..|...||:....:. ...:|.|:|||.::|....|||::|.|||.|||::::|.|:
Human   268 SGCRASVLHQLGSRPRQTLDALLPPDTSPEALDLLRRLLVFAPDKRLSATQALQHPYVQRFHCPS 332

  Fly   319 DE--QTAALYDQSFEENELPVEKWREMVFSEV 348
            ||  :.|.:..::.|..:|.|.::|..|:..:
Human   333 DEWAREADVRPRAHEGVQLSVPEYRSRVYQMI 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p38b	NP_477361.1	STKc_p38	8..353	CDD:143356	135/357 (38%)
		S_TKc	24..311	CDD:214567	124/316 (39%)
MAPK15	XP_011515227.1	STKc_MAPK15-like	25..364	CDD:270841	133/345 (39%)
		S_TKc	25..325	CDD:214567	122/306 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810