back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment p38b and Mapk11

DIOPT Version :9

Sequence 1:	NP_477361.1	Gene:	p38b / 34780	FlyBaseID:	FBgn0024846	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_035291.4	Gene:	Mapk11 / 19094	MGIID:	1338024	Length:	364	Species:	Mus musculus

Alignment Length:	353	Identity:	235/353 - (66%)
Similarity:	284/353 - (80%)	Gaps:	3/353 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSRKMAKFYKLDINRTEWEIPETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHA 65
            ||...|.||:.::|:|.||:|:..|.|:|||.||||.||.|.......|||:|||:|||||.:||
Mouse     1 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHA 65

  Fly    66 KRTYRELRLLKHMDHENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKLSDDHV 130
            :|||||||||||:.|||||||||||   .||.|::.|.:||:||.||.||||||::.|.|||:||
Mouse    66 RRTYRELRLLKHLKHENVIGLLDVF---TPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHV 127

  Fly   131 QFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPAESEMTGYVATRWYRAPE 195
            ||||||:|||||||||||:|||||||||:|||||||||||||||||.|:.|||||||||||||||
Mouse   128 QFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPE 192

  Fly   196 IMLNWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRISSESARN 260
            |||||||||||.|||||||||||||.|:.||||.|:|.||..||||:|||:.|.:::||||.||.
Mouse   193 IMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKISSEHART 257

  Fly   261 YIRSLPVMPRRNFRDIFRGANPLAIDLLEKMLELDADKRITAEQALAHPYMEKYHDPTDEQTAAL 325
            ||:|||.||:::...:|.||||||||||.:||.||:|:|::|.:||||.|..:||||.||..|..
Mouse   258 YIQSLPPMPQKDLSSVFHGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPDDEPEAEP 322

  Fly   326 YDQSFEENELPVEKWREMVFSEVTAFKP 353
            ||:|.|..|..:|:|:|:.:.||.:|||
Mouse   323 YDESVEAKERTLEEWKELTYQEVLSFKP 350

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.