Protein Alignment TM9SF4 and TMN3

DIOPT Version :9

• Sequence 1: NP_001285907.1
• Gene: TM9SF4 / 34778
• FlyBaseID: FBgn0028541
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_011038.3
• Gene: TMN3 / 856849
• SGDID: S000000915
• Length: 706
• Species: Saccharomyces cerevisiae
• Alignment Length: 747
• Identity: 190/747 - (25%)
• Similarity: 321/747 - (42%)
• Gaps: 180/747 - (24%)

  Fly     8 RPCLAIVLLAGVVLV----ADSFYVP-----GVAPVEFVQDQK-----------------IDVKA 46
            ||..:::.|..:|:|    .:.||..     |..|| ....||                 :::..
Yeast     4 RPKRSVITLMAIVVVMLILRNQFYSSRTRGHGQEPV-ISSSQKNLYDGWITPNFYRKGDPLELIV 67

  Fly    47 VKMTSSRTQLPYQYYSLRFCYPKNGTLIFKSE---NLGEVLRGDRIVNTPYEVRMNQQVNCRLLC 108
            .|:.|..|||||.||.|.|..|..   :.|..   :|.|::||||...:.|:::..:...|..||
Yeast    68 NKVESDLTQLPYAYYDLPFTCPPT---MHKKPLHLSLNEIIRGDRKWESDYKLKFGEDNPCETLC 129

  Fly   109 NQKDRPLTWSKEDSALVAERIQHEYFVHLLVDN-LPVATRIVSVNNPAEVTYEHGYRLGQV--DG 170
            .:|.     :||....:.:.::..|.|..|:|: ||.||..:|..:..:. |..|:.||.:  |.
Yeast   130 ARKT-----TKEGMQTLDKLVREGYVVQWLIDDELPAATTFISTTDHKKY-YASGFPLGFIDPDT 188

  Fly   171 DNIYINNHLKFILSYHMHSKDKYRVVGFEVETVSVSHKELKFH--GDTCNFPDSARPQLVNPNGE 233
            |..|::||:..::.:|....||..:|||||...|||    .:|  |.:.|:   .:.::|.|..|
Yeast   189 DKTYLHNHVMLVIRFHASDNDKNTIVGFEVYPRSVS----DYHCPGASKNY---EQYEIVIPEDE 246

  Fly   234 ---TQLYFTYSVEWKES-KVSWASRWDIYLGM------RDVQIHWFSIINSLVVVFFLSGILTMI 288
               |.|.|||||.|:|. :|.|..|||.:|..      :.:|.||.|:.||:.:|..:|.|..:|
Yeast   247 NELTYLPFTYSVYWREEFEVDWNHRWDYFLNAGELSDEQSIQFHWMSLANSVGIVLSISFITLII 311

  Fly   289 MIRTLRRD------------IARYNTDDNIEDTLEETG----------WKLVHGDVFRPPKNTRL 331
            .:|.:..|            |....|:|:::|  ::.|          | :.:|   ||    .|
Yeast   312 YVRVMYTDKSNSKSPKYMINIEGIETEDDLDD--DKYGKYSVYTVAKDW-IQNG---RP----NL 366

  Fly   332 FSAIIGSGIQIFFMAL---ITIFFAMLGMLSPSS--------RGALMTSGIFMYVFMGTIAGYYA 385
            |      |:::..:.:   :...|.::|.|:.|.        |.:::|..|..:|....:|.:..
Yeast   367 F------GLKVLILLVSFGVQFLFTIIGSLTISCSMNKLHNVRNSVLTMAILFFVLGAFMASFVG 425

  Fly   386 ARLYKTMKGREWKRAAFLTATLY-------------------PGIVFGTGFFLNFFIWDKSSSGA 431
            .||....|.:..| |.:|....|                   ||||..:.|.||..:|...|:.|
Yeast   426 TRLSMVTKTKRTK-ANYLDDNRYLKDYKKFSPIFTILCGSSLPGIVMVSTFLLNSIVWAHDSTSA 489

  Fly   432 VPFTTMISLLLLWFGISVPLVYLGFYLGYRKQPYQHPVRTNMIPRQVPTQHWYMNAV-------- 488
            :||.|::..:.::|.:.:||...|                .::...:|...::::.:
Yeast   490 LPFKTIVFFMSIYFIVCIPLSLFG----------------GIVANNIPLPQYWLSGITKDESNSD 538

  Fly   489 ------------------LSTLMAGILPFGAVFIELFFVFTAIW--QNQFYYLFGFLFLVFCILV 533
                              ....:.||.|...:::|:.:|:.::|  :..|||.:|||||...:|.
Yeast   539 GNGLFVPKSRAKFNPLVYCGIYLCGIFPLLVIYVEMQYVYKSLWLEKTTFYYFYGFLFLSIILLC 603

  Fly   534 VSCAQISIVMTY--FQLCGED----YRWWWRSFVVSGGSAVYVLFYSIFYFFTKLEITEFIPTLL 592
            |...:|||:.:|  .:.|.||    ..|.|:.|.:.....||:..||::|.|..|.|..|...|:
Yeast   604 VLTMEISIIGSYLLMRFCFEDKVVRNNWRWKCFEMGFSGGVYMELYSLYYIFAVLNIHGFSSILI 668

  Fly   593 YLGYTGLMVLTFWLLTGSIGFFAAYVFILRIY 624
            .:.|:.:..:...|..|::.:..|..||.:||
Yeast   669 SICYSLIFNVMCSLGLGALSYLTASWFINKIY 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF4	NP_001285907.1	EMP70	57..587	CDD:281048	163/633 (26%)
TMN3	NP_011038.3	EMP70	78..663	CDD:397233	163/633 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10766
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920