Protein Alignment TM9SF4 and TMN2

DIOPT Version :10

• Sequence 1: NP_609669.1
• Gene: TM9SF4 / 34778
• FlyBaseID: FBgn0028541
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_010392.1
• Gene: TMN2 / 851685
• SGDID: S000002514
• Length: 672
• Species: Saccharomyces cerevisiae
• Alignment Length: 671
• Identity: 223/671 - (33%)
• Similarity: 364/671 - (54%)
• Gaps: 83/671 - (12%)

  Fly    26 FYVPGVAPVEFVQDQKIDVKAVKMTSS------------------RTQLPYQYYSLR--FCYPKN 70
            |.:||::|..:....:|.:...::|.|                  .....|.||:.|  ||.|::
Yeast    19 FSLPGLSPTTYHSGDEIPLLVNRLTPSIYFQHQDEEGNDVSGDKEHFLYSYDYYNKRFHFCRPEH 83

  Fly    71 GTLIFKSENLGEVLRGDRIVNTPYEVRMNQQVNCRLLCNQKDRPLTWSKEDSALVAERIQHEYFV 135
              :..:.|:||.|:.||||.|:|:::.|.::..|..||..     |...:|:..:...|:..:|.
Yeast    84 --VEKQPESLGSVIFGDRIYNSPFQLNMLEEKECVALCKS-----TIPGKDAKFINTLIKSGFFQ 141

  Fly   136 HLLVDNLPVATRIVSVNNPAEVTYEHGYRLG------QVDGDNI--------------------- 173
            :.|||.||.|.:.......... |..|:.||      .|||..:
Yeast   142 NWLVDGLPAARKAYDSRTKTNY-YGTGFELGFTDVKQTVDGKAVPSTMEELTSEASNEDVILDAR 205

  Fly   174 ----------------YINNHLKFILSYHMHSKDKYRVVGFEVETVSVSHKELKFHGDTCNFPDS 222
                            |..||....:.:|....|.|||||..|..||:....    ...|:  .:
Yeast   206 LPKNVKPNLVKTVELPYFVNHFDIEVEFHDRGNDNYRVVGVIVNPVSIERSS----PGACS--TT 264

  Fly   223 ARPQLVNPNGETQLYFTYSVEWKESKVSWASRWDIYLGMRDVQIHWFSIINSLVVVFFLSGILTM 287
            .:|.:::.:.:.::||||||::..|...||:|||.||.:.|.||.|||:||..|:|..||.::..
Yeast   265 GKPLILDEDKDNEVYFTYSVKFVASDTVWATRWDKYLHIYDPQIQWFSLINFSVIVILLSSVVMH 329

  Fly   288 IMIRTLRRDIARYNTDDNIEDTL-EETGWKLVHGDVFRPPKNTRLFSAIIGSGIQIFFMALITIF 351
            .::|.|:.|:|||| :.|:::.. |::||||.||||||.|..:.|.|.::|||:|:|.|.:.:||
Yeast   330 SLLRALKSDLARYN-ELNLDNEFHEDSGWKLGHGDVFRTPSKSMLLSILVGSGMQLFLMVMCSIF 393

  Fly   352 FAMLGMLSPSSRGALMTSGIFMYVFMGTIAGYYAARLYKTMKGREWKRAAFLTATLYPGIVFGTG 416
            ||.:|::||.|||:|.|....:|...|.:..|.:..:||..:|..||....||..|.||.:|...
Yeast   394 FAAVGLVSPVSRGSLPTVMFVLYALFGFVGSYASMGVYKFFRGPYWKANMILTPILLPGAIFLLI 458

  Fly   417 FFLNFFIWDKSSSGAVPFTTMISLLLLWFGISVPLVYLGFYLGYRKQPY-QHPVRTNMIPRQVPT 480
            ..:|||:....|||.:|..::..::||||.:||||.:.|..:.:::..: :||.:||.|.||:|.
Yeast   459 VIMNFFLLFAHSSGVIPARSLFFIILLWFLVSVPLSFAGSIVAHKQCNWDEHPTKTNQIARQIPY 523

  Fly   481 QHWYMNAVLSTLMAGILPFGAVFIELFFVFTAIWQNQFYYLFGFLFLVFCILVVSCAQISIVMTY 545
            |.||:....:||:|||..||::.:||:|:::::|.|:.:|:||||...|.:|.::.:.::|::||
Yeast   524 QPWYLRTAQATLIAGIFSFGSIAVELYFIYSSLWFNKIFYMFGFLLFSFLLLTLTTSLVTILITY 588

  Fly   546 FQLCGEDYRWWWRSFVVSG-GSAVYVLFYSIFYFFTKLEITEFIPTLLYLGYTGLMVLTFWLLTG 609
            :.||.|::.|.||||::.| |.::|...:||  .|||.::...|..:|||||:.::.....::||
Yeast   589 YSLCLENWLWQWRSFIIGGLGCSIYTFIHSI--LFTKFKLGGVITVVLYLGYSLIISALCCVVTG 651

  Fly   610 SIGFFAAYVFILRIYGAVKID 630
            :||||::..||.:||.|:|::
Yeast   652 AIGFFSSMFFIRKIYSAIKVE 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF4	NP_609669.1	EMP70	57..587	CDD:460774	198/577 (34%)
TMN2	NP_010392.1	EMP70	68..629	CDD:460774	198/577 (34%)