Protein Alignment TM9SF4 and EMP70

DIOPT Version :9

• Sequence 1: NP_001285907.1
• Gene: TM9SF4 / 34778
• FlyBaseID: FBgn0028541
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_013184.1
• Gene: EMP70 / 850772
• SGDID: S000004073
• Length: 667
• Species: Saccharomyces cerevisiae
• Alignment Length: 675
• Identity: 239/675 - (35%)
• Similarity: 367/675 - (54%)
• Gaps: 74/675 - (10%)

  Fly    13 IVLLAGVVLVADSFYVPGVAPVEFVQDQKIDVKAVKMTSSRTQ------------------LPYQ 59
            ::||...|....:||:|||||..:.::..|.:....:|.|...                  ..|.
Yeast    10 LLLLYFFVSTVKAFYLPGVAPTTYRENDNIPLLVNHLTPSMNYQHKDEDGNNVSGDKENFLYSYD 74

  Fly    60 YYSLR--FCYPKNGTLIFKSENLGEVLRGDRIVNTPYEVRMNQQVNCRLLCNQKDRPLTWSKEDS 122
            ||..|  ||.|:.  :..:.|:||.|:.||||.|:|:::.|.|:..|..||.     .....:|:
Yeast    75 YYYNRFHFCQPEK--VEKQPESLGSVIFGDRIYNSPFQLNMLQEKECESLCK-----TVIPGDDA 132

  Fly   123 ALVAERIQHEYFVHLLVDNLPVATRIVSVNNPAEVTYEHGYRLGQV---DGDNI----------- 173
            ..:.:.|::.:|.:.|:|.||.|..:......... |..|:.||.|   .|.:|
Yeast   133 KFINKLIKNGFFQNWLIDGLPAAREVYDGRTKTSF-YGAGFNLGFVQVTQGTDIEATPKGAETTD 196

  Fly   174 --------------------YINNHLKFILSYHMHSKDKYRVVGFEVETVSVSHKELKFHGDTCN 218
                                |..||...::.||...:..|||||..||.||:....    ..||.
Yeast   197 KDVELETRNDRNMVKTYELPYFANHFDIMIEYHDRGEGNYRVVGVIVEPVSIKRSS----PGTCE 257

  Fly   219 FPDSARPQLVNPNGETQLYFTYSVEWKESKVSWASRWDIYLGMRDVQIHWFSIINSLVVVFFLSG 283
            ...|  |.:::...:.::||||||::.||..|||:|||.||.:.|..|.|||:||..:||..||.
Yeast   258 TTGS--PLMLDEGNDNEVYFTYSVKFNESATSWATRWDKYLHVYDPSIQWFSLINFSLVVVLLSS 320

  Fly   284 ILTMIMIRTLRRDIARYNTDDNIEDTLEETGWKLVHGDVFRPPKNTRLFSAIIGSGIQIFFMALI 348
            ::...::|.|:.|.||||..:..:|..|::||||.||||||.|..:...|.::|||:|:|.|...
Yeast   321 VVIHSLLRALKSDFARYNELNLDDDFQEDSGWKLNHGDVFRSPSQSLTLSILVGSGVQLFLMVTC 385

  Fly   349 TIFFAMLGMLSPSSRGALMTSGIFMYVFMGTIAGYYAARLYKTMKGREWKRAAFLTATLYPGIVF 413
            :||||.||.|||||||:|.|....:|...|.:..|.:..:||...|..||....||..|.||.:.
Yeast   386 SIFFAALGFLSPSSRGSLATVMFILYALFGFVGSYTSMGIYKFFNGPYWKANLILTPLLVPGAIL 450

  Fly   414 GTGFFLNFFIWDKSSSGAVPFTTMISLLLLWFGISVPLVYLGFYLGYRKQPY--QHPVRTNMIPR 476
            .....||||:....|||.:|.:|:..::.|||..|:||.:.|..:. ||:.:  :||.:||.|.|
Yeast   451 LIIIALNFFLMFVHSSGVIPASTLFFMVFLWFLFSIPLSFAGSLIA-RKRCHWDEHPTKTNQIAR 514

  Fly   477 QVPTQHWYMNAVLSTLMAGILPFGAVFIELFFVFTAIWQNQFYYLFGFLFLVFCILVVSCAQISI 541
            |:|.|.||:..:.:||:|||.|||::.:||:|::|::|.|:.:|:|||||..|.:|.::.:.::|
Yeast   515 QIPFQPWYLKTIPATLIAGIFPFGSIAVELYFIYTSLWFNKIFYMFGFLFFSFLLLTLTSSLVTI 579

  Fly   542 VMTYFQLCGEDYRWWWRSFVVSG-GSAVYVLFYSIFYFFTKLEITEFIPTLLYLGYTGLMVLTFW 605
            ::||..||.|:::|.||.|::.| |.|:||..:||  .|||.::..|...:||:||:.::.|...
Yeast   580 LITYHSLCLENWKWQWRGFIIGGAGCALYVFIHSI--LFTKFKLGGFTTIVLYVGYSSVISLLCC 642

  Fly   606 LLTGSIGFFAAYVFILRIYGAVKID 630
            |:||||||.::.:|:.:||.::|:|
Yeast   643 LVTGSIGFISSMLFVRKIYSSIKVD 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF4	NP_001285907.1	EMP70	57..587	CDD:281048	208/568 (37%)
EMP70	NP_013184.1	EMP70	72..624	CDD:397233	208/568 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	380	1.000	Domainoid score	I105
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	429	1.000	Inparanoid score	I278
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoFinder	1	1.000	-	-		FOG0000597
OrthoInspector	1	1.000	-	-		mtm9200
orthoMCL	1	0.900	-	-		OOG6_100462
Panther	1	1.100	-	-	O	PTHR10766
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1983
SonicParanoid	1	1.000	-	-		X358
TreeFam	0	0.000	Not matched by this tool.
	12	11.900