DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TM9SF4 and TMN7

DIOPT Version :9

Sequence 1:	NP_001285907.1	Gene:	TM9SF4 / 34778	FlyBaseID:	FBgn0028541	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_187991.1	Gene:	TMN7 / 820587	AraportID:	AT3G13772	Length:	641	Species:	Arabidopsis thaliana

Alignment Length:	630	Identity:	314/630 - (49%)
Similarity:	426/630 - (67%)	Gaps:	39/630 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 SFYVPGVAPVEFVQDQKIDVKAVKMTSSRTQLPYQYYSLRFCYPKNGTLIFKSENLGEVLRGDRI 89
            :||:|||||.:|.:...:.||..|::|::|||||.||.|.:|.|..  ::..:||||||||||||
plant    27 AFYLPGVAPRDFQKGDPLYVKVNKLSSTKTQLPYDYYYLNYCKPPK--ILNNAENLGEVLRGDRI 89

  Fly    90 VNTPYEVRMNQQVNCRLLCNQKDRPLTWSKEDSALVAERIQHEYFVHLLVDNLPVATRIVSVNNP 154
            .|:.|..:|.:...|::.|..|     .:.:.:....|:|..||..::::||||||......:..
plant    90 ENSVYTFQMLEDQPCKVGCRVK-----LNADSTKNFKEKIDDEYRANMILDNLPVAVLRQRRDGS 149

  Fly   155 AEVTYEHGYRL---GQVDG---DNIYINNHLKFILSYHM-HSKDKYRVVGFEVETVSVSHKELKF 212
            ...|||||:|:   |..:|   :..:|:|||.|.:.||. ...|..|:|||||...|:.|:..::
plant   150 QSTTYEHGFRVGFKGSYEGSKEEKYFIHNHLSFRVMYHRDQESDSARIVGFEVTPNSILHEYKEW 214

  Fly   213 HGDTCNFPDSARPQLVNPNGET-----------------QLYFTYSVEWKESKVSWASRWDIYLG 260
                    |...|||...|.:|                 ::.|||.|.:|||::.||||||.||.
plant   215 --------DEKNPQLTTCNKDTKNLIQGNTVPQEVEQGKEIVFTYDVSFKESEIKWASRWDTYLL 271

  Fly   261 MRDVQIHWFSIINSLVVVFFLSGILTMIMIRTLRRDIARYNTDDNIEDTLEETGWKLVHGDVFRP 325
            |.|.|||||||||||::|.||||::.|||:|||.:||:.||..:..::..|||||||||||||||
plant   272 MNDDQIHWFSIINSLMIVLFLSGMVAMIMMRTLYKDISNYNQLETQDEAQEETGWKLVHGDVFRP 336

  Fly   326 PKNTRLFSAIIGSGIQIFFMALITIFFAMLGMLSPSSRGALMTSGIFMYVFMGTIAGYYAARLYK 390
            |.|:.|....:|:|:|||.|:|:|:.||:||.||||:||.|||:.:.::||||..|||.::||:|
plant   337 PVNSGLLCVYVGTGVQIFGMSLVTMMFALLGFLSPSNRGGLMTAMVLLWVFMGIFAGYSSSRLHK 401

  Fly   391 TMKGREWKRAAFLTATLYPGIVFGTGFFLNFFIWDKSSSGAVPFTTMISLLLLWFGISVPLVYLG 455
            ..||.:|||....||.::|||:|...|.||..||.:.||||:||.||.:|..||||||||||::|
plant   402 MFKGNKWKRMTLKTAFMFPGILFAIFFVLNALIWGEQSSGAIPFGTMFALFCLWFGISVPLVFVG 466

  Fly   456 FYLGYRKQPYQHPVRTNMIPRQVPTQHWYMNAVLSTLMAGILPFGAVFIELFFVFTAIWQNQFYY 520
            .||||:|...:.||:||.||||||.|.|||..|.|.|:.||||||||||||||:.|:||.|||||
plant   467 SYLGYKKPAIEDPVKTNKIPRQVPEQPWYMKPVFSILIGGILPFGAVFIELFFILTSIWLNQFYY 531

  Fly   521 LFGFLFLVFCILVVSCAQISIVMTYFQLCGEDYRWWWRSFVVSGGSAVYVLFYSIFYFFTKLEIT 585
            :|||||:||.||:|:||:|::|:.|||||.|||.||||:::.:|.||.|:..|||||||||||||
plant   532 IFGFLFIVFLILIVTCAEITVVLCYFQLCSEDYNWWWRAYLTAGSSAFYLFLYSIFYFFTKLEIT 596

  Fly   586 EFIPTLLYLGYTGLMVLTFWLLTGSIGFFAAYVFILRIYGAVKID 630
            :.:..:||.||..::...|::|||:|||:|.:.|:.:||.:||||
plant   597 KLVSGMLYFGYMIIISYAFFVLTGTIGFYACFWFVRKIYSSVKID 641

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF4	NP_001285907.1	EMP70	57..587	CDD:281048	280/553 (51%)
TMN7	NP_187991.1	EMP70	59..598	CDD:397233	280/553 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	569	1.000	Domainoid score	I44
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H21620
Inparanoid	1	1.050	649	1.000	Inparanoid score	I171
OMA	1	1.010	-	-		QHG53553
OrthoDB	1	1.010	-	-		D641127at2759
OrthoFinder	1	1.000	-	-		FOG0000597
OrthoInspector	1	1.000	-	-		otm3057
orthoMCL	1	0.900	-	-		OOG6_100462
Panther	1	1.100	-	-	O	PTHR10766
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X358
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840