DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TM9SF4 and AT2G24170

DIOPT Version :9

Sequence 1:	NP_001285907.1	Gene:	TM9SF4 / 34778	FlyBaseID:	FBgn0028541	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_179994.2	Gene:	AT2G24170 / 816951	AraportID:	AT2G24170	Length:	637	Species:	Arabidopsis thaliana

Alignment Length:	643	Identity:	321/643 - (49%)
Similarity:	440/643 - (68%)	Gaps:	41/643 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 IVLLAGVVLVADSFYVPGVAPVEFVQDQKIDVKAVKMTSSRTQLPYQYYSLRFCYPKNGTLIFKS 77
            :||...:.:....||:|||||.:|.....:.||..|:||::|||||.||||.:|.|::  ::..:
plant    11 LVLFFSLNVHIHGFYLPGVAPQDFQMGDALMVKVNKLTSTKTQLPYSYYSLPYCRPEH--IVDSA 73

  Fly    78 ENLGEVLRGDRIVNTPYEVRMNQQVNCRLLCNQKDRPLTWSKEDSALVAERIQHEYFVHLLVDNL 142
            ||||||||||||.|:|:..:|.:...|..:|..|     ..|:.:....|:|..||.|::::|||
plant    74 ENLGEVLRGDRIENSPFVFKMRESQMCAAVCRVK-----LDKKTAKAFKEKIADEYRVNMILDNL 133

  Fly   143 PVATRIVSVNNPAE---VTYEHGYRLGQVDG-------DNIYINNHLKFILSYHMH-SKDKYRVV 196
            |:   :|.|..|.:   |.|:||:.:| :.|       :..:|:|||.|.:.||.. ..|..|:|
plant   134 PL---VVPVQRPDQDNVVVYQHGFHVG-LKGIFAGKKEEKYFIHNHLTFTVRYHRDIQTDSSRIV 194

  Fly   197 GFEVETVSVSHKELKFHGD--------TCN------FPDSARPQLVNPNGETQLYFTYSVEWKES 247
            ||||:..||.|   ::.|.        ||:      ..:|..||.|....|  :.|||.|:::||
plant   195 GFEVKPFSVKH---EYEGQWNEKARLTTCDPHTKRAVTNSESPQEVEEGNE--IIFTYDVDFQES 254

  Fly   248 KVSWASRWDIYLGMRDVQIHWFSIINSLVVVFFLSGILTMIMIRTLRRDIARYNTDDNIEDTLEE 312
            :|.||||||.||.|.|.|||||||:||:::|.||||::.|||:|||.|||:.||..::.|:.|||
plant   255 EVKWASRWDTYLLMADDQIHWFSIVNSMMIVLFLSGMVAMIMLRTLYRDISNYNQLESHEEALEE 319

  Fly   313 TGWKLVHGDVFRPPKNTRLFSAIIGSGIQIFFMALITIFFAMLGMLSPSSRGALMTSGIFMYVFM 377
            ||||||||||||||.|..|.....|:|:|.|.|.|:|:.||.||.||||:||.|||:.:.::|||
plant   320 TGWKLVHGDVFRPPTNPELLCVYAGTGVQCFGMILVTMIFACLGFLSPSNRGGLMTAMLLLWVFM 384

  Fly   378 GTIAGYYAARLYKTMKGREWKRAAFLTATLYPGIVFGTGFFLNFFIWDKSSSGAVPFTTMISLLL 442
            |.:|||.::|||||::|.||||.|..||.::|..||...|.||..||.:.|||||||.||.:|::
plant   385 GLLAGYASSRLYKTLRGTEWKRNALKTAFMFPATVFVAFFVLNAIIWGQKSSGAVPFGTMFALVV 449

  Fly   443 LWFGISVPLVYLGFYLGYRKQPYQHPVRTNMIPRQVPTQHWYMNAVLSTLMAGILPFGAVFIELF 507
            ||||||||||::|.|:|:||...:.||:||.||||:|||.||||.:.|.|:.|||||||||||||
plant   450 LWFGISVPLVFIGGYIGFRKPAPEDPVKTNKIPRQIPTQAWYMNPIFSILIGGILPFGAVFIELF 514

  Fly   508 FVFTAIWQNQFYYLFGFLFLVFCILVVSCAQISIVMTYFQLCGEDYRWWWRSFVVSGGSAVYVLF 572
            |:.|:||.:||||:|||||:||.||:::||:|::|:.|||||.|||:|||||::.||.||||:..
plant   515 FILTSIWLHQFYYIFGFLFIVFIILIITCAEITVVLCYFQLCSEDYQWWWRSYLTSGSSAVYLFL 579

  Fly   573 YSIFYFFTKLEITEFIPTLLYLGYTGLMVLTFWLLTGSIGFFAAYVFILRIYGAVKID 630
            |::|||:||||||:.:..:||.||..::...|::.||:|||:|.:.|...||.:||||
plant   580 YAVFYFYTKLEITKLVSAVLYFGYMLIVSYVFFVFTGAIGFYACFWFTRLIYSSVKID 637

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF4	NP_001285907.1	EMP70	57..587	CDD:281048	285/554 (51%)
AT2G24170	NP_179994.2	EMP70	55..594	CDD:367285	285/554 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	569	1.000	Domainoid score	I44
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	649	1.000	Inparanoid score	I171
OMA	1	1.010	-	-		QHG53553
OrthoDB	1	1.010	-	-		D641127at2759
OrthoFinder	1	1.000	-	-		FOG0000597
OrthoInspector	1	1.000	-	-		otm3057
orthoMCL	1	0.900	-	-		OOG6_100462
Panther	1	1.100	-	-	O	PTHR10766
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X358
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840