DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TM9SF4 and AT2G01970

DIOPT Version :9

Sequence 1:	NP_001285907.1	Gene:	TM9SF4 / 34778	FlyBaseID:	FBgn0028541	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_178306.1	Gene:	AT2G01970 / 814728	AraportID:	AT2G01970	Length:	592	Species:	Arabidopsis thaliana

Alignment Length:	583	Identity:	200/583 - (34%)
Similarity:	325/583 - (55%)	Gaps:	54/583 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 YQYYSLRFCYPKNGTLIFKSENLGEVLRGDRIVNTPYEVRMNQQVNCRLLCNQKDRPLTWSKEDS 122
            |:|:.|.||.|:.  :..|.|.|||||.|||:|:.||::....:.:..:.|.:|     .|:|:.
plant    54 YRYFDLPFCIPEG--VKDKKEALGEVLNGDRLVSAPYKLNFRDEKDSEVYCKKK-----LSREEV 111

  Fly   123 ALVAERIQHEYFVHLLVDNLPVATRIVSV-----NNPAEVTYEHGYRLGQVDGDNIYINNHLKFI 182
            ......::.:|:..:..|:||:...|..|     ::|:|..|              ::..|::|.
plant   112 EHFRRAVEKDYYFQMYYDDLPIWGFIGKVDKESKSDPSEFKY--------------FLYKHIQFE 162

  Fly   183 LSYHMHSKDKYRVVGFEVETVSVSHKELKFHGDTCNFPDSARPQLVNPNGETQLYFTYSVEWKES 247
            :.|     :|.||:            |:....|..:..|      :..:.|....|.|:|:|||:
plant   163 ILY-----NKDRVI------------EINARMDPHSLVD------LTEDKEVDAEFMYTVKWKET 204

  Fly   248 KVSWASRWDIYLGM----RDVQIHWFSIINSLVVVFFLSGILTMIMIRTLRRDIARYNTDDNIED 308
            :.|:..|.|.|...    ..::|||||||||.|.|..|:|.|..|::|.|:.|..:|..|:...|
plant   205 ETSFEKRMDKYAMSSSLPHHLEIHWFSIINSCVTVLLLTGFLATILMRVLKNDFMKYAQDEEAAD 269

  Fly   309 TLEETGWKLVHGDVFRPPKNTRLFSAIIGSGIQIFFMALITIFFAMLGMLSPSSRGALMTSGIFM 373
            ..||||||.:||||||.|||..||:|.:|||.|:|.:.:.....:::|:..|.:||||.|:.:.:
plant   270 DQEETGWKYIHGDVFRFPKNKSLFAASLGSGTQLFTLTIFIFMLSLVGVFYPYNRGALFTALVVI 334

  Fly   374 YVFMGTIAGYYAARLYKTMKGREWKRAAFLTATLYPGIVFGTGFFLNFFIWDKSSSGAVPFTTMI 438
            |.....||||.|:..|..::|:.|.|...||..|:.|.:|.|..|||......|::.|:||.|:|
plant   335 YALTSGIAGYTASSFYCQLEGKNWVRNLLLTGGLFCGPLFLTFCFLNTVAIAYSATAALPFGTII 399

  Fly   439 SLLLLWFGISVPLVYLGFYLGYR-KQPYQHPVRTNMIPRQVPTQHWYMNAVLSTLMAGILPFGAV 502
            .::|:|..::.||:.||...|.. |..:|.||||...||::|...||.:||....|||.|||.|:
plant   400 VIVLIWTLVTSPLLVLGGIAGKNSKAEFQAPVRTTKYPREIPPLPWYRSAVPQMAMAGFLPFSAI 464

  Fly   503 FIELFFVFTAIWQNQFYYLFGFLFLVFCILVVSCAQISIVMTYFQLCGEDYRWWWRSFVVSGGSA 567
            :|||:::|.::|.::.|.::..||:||.||::..|.|::.:|||||..||:.||||||:..|.:.
plant   465 YIELYYIFASVWGHRIYTIYSILFIVFIILLIVTAFITVALTYFQLAAEDHEWWWRSFLCGGSTG 529

  Fly   568 VYVLFYSIFYFFTKLEITEFIPTLLYLGYTGLMVLTFWLLTGSIGFFAAYVFILRIYGAVKID 630
            :::..|.::|::.:.:::.|:.|..:.||...:...|:|:.|::||.||.:|:..||.::|.:
plant   530 LFIYAYCLYYYYARSDMSGFMQTSFFFGYMACICYGFFLMLGTVGFRAALLFVRHIYRSIKCE 592

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF4	NP_001285907.1	EMP70	57..587	CDD:281048	185/538 (34%)
AT2G01970	NP_178306.1	EMP70	54..549	CDD:397233	185/538 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoDB	1	1.010	-	-		D641127at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830