Protein Alignment TM9SF4 and Tm9sf1

DIOPT Version :9

• Sequence 1: NP_001285907.1
• Gene: TM9SF4 / 34778
• FlyBaseID: FBgn0028541
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001346992.1
• Gene: Tm9sf1 / 74140
• MGIID: 1921390
• Length: 606
• Species: Mus musculus
• Alignment Length: 643
• Identity: 212/643 - (32%)
• Similarity: 327/643 - (50%)
• Gaps: 72/643 - (11%)

  Fly    10 CLAIVLLA-----GVVLVADSFYVPGVAPVEFVQDQKIDVKAVKMTSSRTQLPYQYYSLRFCYPK 69
            ||.:::|.     |..:...:.|.||...:.:|  .|:.      .....|..|.||.|..|.|:
Mouse    14 CLPVLILLLGIGHGPWVEGVTHYKPGDPVILYV--NKVG------PYHNPQETYHYYQLPVCCPE 70

  Fly    70 NGTLIFKSENLGEVLRGDRIVNTPYEVRMNQQVNCRLLCNQKDRPLTWSKEDSALVAERIQHEYF 134
            .  :..||.:|||||.|||:..:.||:|..:.|..|:||:     :..|......:.:.|:..|:
Mouse    71 K--IRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCH-----MQLSSAQVEQLRQAIEELYY 128

  Fly   135 VHLLVDNLPVATRIVSVNNPAEVTYEHGYRLGQVDGDNIYINNHLKFILSYHMHSKDKYRVVGFE 199
            ...:||:||:...:..:.....:.:.|          .|.:..||.|.|.:|          |..
Mouse   129 FEFVVDDLPIRGFVGYMEESGFLPHSH----------KIGLWTHLDFHLEFH----------GDR 173

  Fly   200 VETVSVSHKELKFHGDTCNFPDSAR-PQLVNPNGETQLYFTYSVEWKESKVSWASRWDIYLG--- 260
            :...:||.:::|.|.     .|..| .:|:.      |..||||.|.|:.|.  .|.|...|
Mouse   174 IIFANVSVRDVKPHS-----LDGLRSDELLG------LTHTYSVRWSETSVE--HRSDRRRGDDG 225

  Fly   261 ---MRDVQIHWFSIINSLVVVFFLSGILTMIMIRTLRRDIARYNTDDNI-----EDTLE--ETGW 315
               .|.::|||.|||||:|:||.|.|.:.:|::|.||.|:||||.|:..     .|..:  :.||
Mouse   226 GFFPRTLEIHWLSIINSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETSSGGSSDDFDQGDNGW 290

  Fly   316 KLVHGDVFRPPKNTRLFSAIIGSGIQIFFMALIT--IFFAMLGMLSPSSRGALMTSGIFMYVFMG 378
            |::|.||||.|....|..|::|.|.|  |:||.|  |..|:|||.:....||:.::.|.:|....
Mouse   291 KIIHTDVFRFPPYRGLLCAVLGVGAQ--FLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTC 353

  Fly   379 TIAGYYAARLYKTMKGREWKRAAFLTATLYPGIVFGTGFFLNFFIWDKSSSGAVPFTTMISLLLL 443
            .|:||.::..|:.:.|..|.....||::|:....|.|...:|...|...|:.|:|.||::.||.:
Mouse   354 CISGYVSSHFYRQIGGERWVWNIILTSSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTV 418

  Fly   444 WFGISVPLVYLGFYLGYRK-QPYQHPVRTNMIPRQVPTQHWYMNAVLSTLMAGILPFGAVFIELF 507
            |..:..||..:|...|... .|:..|.||..|.|::|.|.||.:.|:...:.|.|||.|:.:||:
Mouse   419 WLLVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLPFSAISVELY 483

  Fly   508 FVFTAIWQNQFYYLFGFLFLVFCILVVSCAQISIVMTYFQLCGEDYRWWWRSFVVSGGSAVYVLF 572
            ::|..:|..:.|.|:|.||.||.||:...|.|||.:|||||.||||||||||.:..|.:.:::..
Mouse   484 YIFATVWGREQYTLYGILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFL 548

  Fly   573 YSIFYFFTKLEITEFIPTLLYLGYTGLMVLTFWLLTGSIGFFAAYVFILRIYGAVKID 630
            ||:||:..:..::..:.|:.:.||:.|....|:|:.|:|.||::..||..||..:|:|
Mouse   549 YSVFYYARRSNMSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF4	NP_001285907.1	EMP70	57..587	CDD:281048	186/546 (34%)
Tm9sf1	NP_001346992.1	EMP70	59..562	CDD:367285	186/544 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoDB	1	1.010	-	-		D135708at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830